Search results for "Library"

Human Siglec-10 can bind to vascular adhesion protein-1 and serves as its substrate

2009

AbstractLeukocytes migrate from the blood into areas of inflammation by interacting with various adhesion molecules on endothelial cells. Vascular adhesion protein-1 (VAP-1) is a glycoprotein expressed on inflamed endothelium where it plays a dual role: it is both an enzyme that oxidizes primary amines and an adhesin that is involved in leukocyte trafficking to sites of inflammation. Although VAP-1 was identified more than 15 years ago, the counterreceptor(s) for VAP-1 on leukocytes has remained unknown. Here we have identified Siglec-10 as a leukocyte ligand for VAP-1 using phage display screenings. The binding between Siglec-10 and VAP-1 was verified by different adhesion assays, and this…

Complete coding nucleotide sequence of cDNA for the class II RT1.B beta I chain of the Lewis rat.

1991

We have established the first full length cDNA clone for the beta light chain of the MHC class II alpha, beta heterodimer (isotype RT1.B) of the rat. Clone pLR beta 118 was obtained from a self-primed lambda gt10 cDNA library of IFN-tau treated bone marrow-derived macrophages of the Lewis rat. Subcloning of pLR beta 118 into a transcription vector with subsequent in vitro transcription and translation using the reticulocyte lysate system in the presence of microsomes followed by immunoprecipitation with mAb OX6 and two-dimensional gel electrophoresis revealed the intact RT1.B beta I-chain.

Dissemination of Spanish Social Sciences and Humanities Journals

2005

The presence of scholarly journals in international data bases promotes the dissemination of research results and also facilitates requests for specific articles or journals by end users. As scientists seek optimal visibility for their work and wish their results to be published in journals with high circulation, it is important to know which are the leading journals within each scientific area. This paper contains a bibliometric study of scientific journals in the areas of Social Sciences and Humanities that are currently published in Spain, together with information concerning their production and circulation in the different national and international bibliographical data bases, publishe…

Bibliometric profile of the global scientific research on multiple sclerosis (2003-2012)

2015

[Background and objectives]: The aim of this paper is to analyse the scientific research on multiple sclerosis using a bibliographic analysis of articles published during the period 2003-2012. [Methods]: The items under study were obtained from the Science Citation Index-Expanded (SCI-E) database, which was accessed through the Web of Science (WOS) platform. All records with the term multiple sclerosis in the title, plus all articles published in the journals Multiple Sclerosis and Multiple Sclerosis Journal, were analysed. [Results]: A total of 9778 articles, with 160,966 citations, were retrieved on multiple sclerosis, and the majority of the articles were published in Multiple Sclerosis …

A lab in the field: applications of real-time, in situ metagenomic sequencing

2020

High-throughput metagenomic sequencing is considered one of the main technologies fostering the development of microbial ecology. Widely used second-generation sequencers have enabled the analysis of extremely diverse microbial communities, the discovery of novel gene functions, and the comprehension of the metabolic interconnections established among microbial consortia. However, the high cost of the sequencers and the complexity of library preparation and sequencing protocols still hamper the application of metagenomic sequencing in a vast range of real-life applications. In this context, the emergence of portable, third-generation sequencers is becoming a popular alternative for the rapi…

Technologies for attention to diversity: a bibliometric study

2019

[EN] In these last decades, digital systems and playful dynamics have penetrated the inclusive education field, in some cases to attend the diversity of the classroom as a whole and, in others, to study in a specific way the use of technologies in students with special needs. About this topic, on the following pages we study the trends of the research carried out through a bibliometric analysis of the scientific production in the Scopus database, which includes an amount of 59 articles, published between 1999 and 2019, are included. The results indicate an increase in the last years of the presence of scientific publications in journals in the field of Social Sciences. Furthermore, data sho…

Cache-cache démocratique. Les Gilets jaunes, de l'invisible à l'inaudible.

2020

International audience

Viktigheten av fysisk aktivitet og trening blant eldre

2012

Published version of an article in the journal: Norsk Epidemiologi. Also available from the publisher at: http://www.ntnu.no/ojs/index.php/norepid/article/view/1562 Open access Regular physical activity in older adults is critically important to ensure healthy aging. The link between physical activity and prevention of disease, maintenance of independence, and improved quality of life is supported by strong evidence (ACSM's Position Stand 1998; Spirduso & Cronin, 2001; Taylor et al., 2004). The purpose of this review is therefore to clarify the importance of regular physical activity and training during the aging process and in addition, present the relationship between a physical active li…

2019

Abstract This paper presents an index that measures reviewer contribution to editorial processes of scholarly journals. Following a metaphor of ranking algorithms in sports tournaments, we created an index that considers reviewers on different context-specific dimensions, i.e., report delivery time, the length of the report and the alignment of recommendations to editorial decisions. To test the index, we used a dataset of peer review in a multi-disciplinary journal, including 544 reviewers on 606 submissions in six years. Although limited by sample size, the test showed that the index identifies outstanding contributors and weak performing reviewers efficiently. Our index is flexible, cont…

[Coauthorship networks and institutional collaboration in Farmacia Hospitalaria].

2009

Abstract Background Scientific collaboration is necessary for the advance of science. The purpose of this study is to analyze collaboration between authors and Spanish institutions in scientific studies published in Farmacia Hospitalaria, applying methodology derived from the analysis of social networks. Methodology The study identified pairs of authors and institutions co-authoring or co-signing the same works published in Farmacia Hospitalaria between 1998 and 2007, building collaboration networks using the TextToPajek and Networks-PAJEK programs. Results 448 articles were analyzed, showing an average signature/article index of 4.79. Applying a collaboration threshold of 3 articles, 26 cl…