Search results for "Life cycle"
showing 10 items of 378 documents
The ACRIDICON-CHUVA campaign: Studying tropical deep convective clouds and precipitation over Amazonia using the new German research aircraft HALO
2016
Abstract Between 1 September and 4 October 2014, a combined airborne and ground-based measurement campaign was conducted to study tropical deep convective clouds over the Brazilian Amazon rain forest. The new German research aircraft, High Altitude and Long Range Research Aircraft (HALO), a modified Gulfstream G550, and extensive ground-based instrumentation were deployed in and near Manaus (State of Amazonas). The campaign was part of the German–Brazilian Aerosol, Cloud, Precipitation, and Radiation Interactions and Dynamics of Convective Cloud Systems–Cloud Processes of the Main Precipitation Systems in Brazil: A Contribution to Cloud Resolving Modeling and to the GPM (Global Precipitatio…
New Business Models for innovating the cork sector and contrasting cork oak woodland abandonment
2021
The traditional agro-silvo-pastoral system is characterized by wooded grasslands derived from human-induced transformation of forests by tree clearing and tillage. One of the most common tree species of agro-silvo-pastoral systems in Sicily is cork oak (Quercus suber L.). According to the regional inventory these species cover 18830 ha (Camerano et al., 2011) from sea level up to 600 m a.s.l. in siliceous and volcanic substrates. Traditional management of cork oak forest is an example of integration of sustainable land use and biodiversity conservation. Cork oak woodlands are ecologically sensitive and maintained by active human management. Currently, this ecosystem in the Mediterranean Bas…
Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms.
2019
Mitochondria have been increasingly recognized as a central regulatory nexus for multiple metabolic pathways, in addition to ATP production via oxidative phosphorylation (OXPHOS). Here we show that inducing mitochondrial DNA (mtDNA) stress in Drosophila using a mitochondrially-targeted Type I restriction endonuclease (mtEcoBI) results in unexpected metabolic reprogramming in adult flies, distinct from effects on OXPHOS. Carbohydrate utilization was repressed, with catabolism shifted towards lipid oxidation, accompanied by elevated serine synthesis. Cleavage and translocation, the two modes of mtEcoBI action, repressed carbohydrate rmetabolism via two different mechanisms. DNA cleavage activ…
Ligand-based discovery of novel trypanosomicidal drug-like compounds: In silico identification and experimental support
2010
Abstract Two-dimensional bond-based linear indices and linear discriminant analysis are used in this report to perform a quantitative structure–activity relationship study to identify new trypanosomicidal compounds. A database with 143 anti-trypanosomal and 297 compounds having other clinical uses, are utilized to develop the theoretical models. The best discriminant models computed using bond-based linear indices provides accuracies greater than 90 for both training and test sets. Our models identify as anti-trypanosomals five out of nine compounds of a set of already-synthesized substances. The in vitro anti-trypanosomal activity of this set against epimastigote forms of Trypanosoma cruzi…
SUP R DSS: A sustainability-based decision support & system for road pavements
2019
Road pavement community members are increasingly becoming aware of the need to incorporating the principles of sustainable development into the sector. Policies are also going in this direction and as a consequence in the recent years researchers and practitioners are coming up with new materials, technologies and practices designed to reduce the negative impacts of their activities in the surroundings. Within this framework the road pavements sector is witnessing a paradigm shift towards the development of pavement technologies incorporating high-content of recycled materials, as well as best practices to decrease the overall carbon footprint. These are all promising solutions that to the …
Life Cycle Assessment of a compact Desiccant Evaporative Cooling system: The case study of the “Freescoo”
2016
Abstract The paper aims at exploring the performances of a compact Desiccant Evaporative Cooling system called “Freescoo” (Free Solar Cooling) in comparison to standard conventional technologies. The Freescoo – that aims at applications in the residential sector and in small office buildings and includes a photovoltaic–thermal system – is analyzed, its monitored performance discussed and reported: under cooling conditions an Energy Efficiency Ratio of 12.8 is calculated, that reaches 50.7 if also photovoltaic generation is considered. To assess the performance of the proposed system a Life Cycle Assessment study was performed to investigate the system covering all its life, from the product…
Within-host evolution decreases virulence in an opportunistic bacterial pathogen
2015
Abstract Background Pathogens evolve in a close antagonistic relationship with their hosts. The conventional theory proposes that evolution of virulence is highly dependent on the efficiency of direct host-to-host transmission. Many opportunistic pathogens, however, are not strictly dependent on the hosts due to their ability to reproduce in the free-living environment. Therefore it is likely that conflicting selection pressures for growth and survival outside versus within the host, rather than transmission potential, shape the evolution of virulence in opportunists. We tested the role of within-host selection in evolution of virulence by letting a pathogen Serratia marcescens db11 sequent…
Life cycle assessment of roads: Material and process related energy savings
2018
The need for climate change mitigation calls for significant actions to match the sustainable development goals and, in this context, road construction and management play a relevant role (cf. EU Green Public Procurement Criteria for Road Design, Construction and Maintenance and Environmental Product Declarations - EPD). In such a context, the role of the Life Cycle Assessment (LCA) methodology is broadly recognized as a tool to quantify sustainability of processes and systems. This study aims at calculating the life-cycle energy and carbon footprint of a typical Italian urban road, including materials production, transportation, construction, maintenance, and rehabilitation. The LCA approa…
Development of eco-friendly processes for the synthesis of biobased solvents and organocatalysts
2018
Oxazolidinones are promising compounds for industrial applications, but nowadays there is not convenient method to produce them on large scale, because of the use of reactants and metallic catalysts harmful for health and environment. A new synthesis method of these compounds was thus elaborated using aminoalcohols and diethyl carbonate. This reaction is catalysed by a biobased imidazolium hydrogen carbonate which is produced by an electrochemical pathway in order to reduce its impact on the environment.This oxazolidinones synthesis method was then applied to the synthesis of a biobased oxazolidinone. To achieve this, an aminoalcohol synthesis was realised, and its structure was established…
Life cycle assessment of a new industrial process for sustainable construction materials
2023
One of the key sectors for the green transition of European countries is construction, that is more and more asked to evolve towards innovative ecological binders and green cost-effective processes. The construction sector is highly energy intensive, and the cement production is one of the main sources of environmental pollution in the world. In this regard, GeoPolymers (GP) seem to be promising for a sustainable replacement of cementitious materials. Therefore, the Life Cycle Assessment (LCA) of the industrial production of different formulations of Geopolymer Concrete (GC) was performed in this study after scaling up the Life Cycle Inventory (LCI) from a laboratory scale to an industrial …