Search results for "Ligament"

showing 10 items of 176 documents

Fracture Mechanics of Collagen Fibrils: Influence of Natural Cross-Links

2013

AbstractTendons are important load-bearing structures, which are frequently injured in both sports and work. Type I collagen fibrils are the primary components of tendons and carry most of the mechanical loads experienced by the tissue, however, knowledge of how load is transmitted between and within fibrils is limited. The presence of covalent enzymatic cross-links between collagen molecules is an important factor that has been shown to influence mechanical behavior of the tendons. To improve our understanding of how molecular bonds translate into tendon mechanics, we used an atomic force microscopy technique to measure the mechanical behavior of individual collagen fibrils loaded to failu…

AdultMaleTailMechanical PhenomenaBiophysicsModulusFibrilta3111Collagen fibrilPatellar LigamentTensile StrengthUltimate tensile strengthmedicineAnimalsHumansMolecular Machines Motors and Nanoscale Biophysicsta315Mechanical PhenomenaChemistryFracture mechanicsta3141AnatomyHydrogen-Ion ConcentrationMiddle Agedmusculoskeletal systemTendonBiomechanical PhenomenaRatsmedicine.anatomical_structureSolubilityBiophysicsCollagenType I collagenBiophysical Journal
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Perihepatic lymph nodes and antiviral response in chronic HCV-associated hepatitis.

2003

To identify predictive factors of response to interferon alpha (IFN-alpha) plus ribavirin therapy in patients with chronic hepatitis C (CHC), the presence of lymphadenopathy (LyA) of the hepatoduodenal ligament and other variables were investigated. A total of 110 patients with histologically proven CHC were enrolled in this study. Ultrasound (US) was performed at the start and end of therapy and 6 months after stopping therapy. At baseline, LyA was present in 35 (43.7%) of 80 patients with alanine aminotransferase (ALT) values and grading was significantly higher than in the LyA-negative group. LyA was more frequent in nonresponders (nonR) than in relapsers (relR) or sustained responders (…

AdultMalemedicine.medical_specialtyAcoustics and UltrasonicsEnd of therapyBiophysicsAlpha interferonGastroenterologyAntiviral Agentschemistry.chemical_compoundInternal medicineRibavirinmedicineHumansUltrasound Lymphadenopathy Chronic hepatitis C Treatment Predictive factors.Radiology Nuclear Medicine and imagingProspective StudiesAlanine aminotransferaseLymph nodeLymphatic DiseasesUltrasonographyHepatitisRadiological and Ultrasound Technologybusiness.industryRibavirinInterferon-alphaHepatoduodenal ligamentHepatitis C ChronicMiddle Agedmedicine.diseasePrognosisSurgerymedicine.anatomical_structureLogistic ModelsTreatment OutcomechemistryDrug Therapy CombinationFemaleLymphbusinessUltrasound in medicinebiology
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Meniscal ramp lesions: diagnostic performance of MRI with arthroscopy as reference standard

2021

Abstract Background The posteromedial meniscal region is gaining interest among orthopedic surgeons, as lesions of this area has been reported to be significantly associated with anterior cruciate ligament tears. The current imaging literature is unclear. Purpose To evaluate the diagnostic performance of MR in the detection of meniscal ramp lesions having arthroscopy as reference standard. Materials and methods We retrospectively included 56 patients (mean age of 25 ± 7 years; 14 females) from January to November 2017 with a arthroscopically proved ACL tear and posterior meniscocapsular separation. On preoperative MRI, two radiologists with 13 and 2 years’ experience in musculoskeletal imag…

AdultMalemedicine.medical_specialtyAdolescentMeniscus (anatomy)Lesion03 medical and health sciencesArthroscopyYoung Adult0302 clinical medicineACL injuries; Anatomy; Arthroscopy; Meniscus; MRI; Adolescent; Adult; Anterior Cruciate Ligament Injuries; Arthroscopy; Female; Humans; Male; Reference Standards; Retrospective Studies; Tibial Meniscus Injuries; Young Adult; Magnetic Resonance ImagingmedicineHumansRadiology Nuclear Medicine and imagingMeniscusNeuroradiologyRetrospective StudiesACL injuries030222 orthopedicsmedicine.diagnostic_testbusiness.industryAnterior Cruciate Ligament InjuriesArthroscopyUltrasoundInterventional radiology030229 sport sciencesGeneral MedicineReference StandardsMagnetic Resonance ImagingTibial Meniscus InjuriesBruisemedicine.anatomical_structureMusculoskeletal RadiologyOrthopedic surgeryFemalemedicine.symptomAnatomySettore MED/36 - Diagnostica Per Immagini E RadioterapiaNuclear medicinebusinessMRI
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Temporomandibular disorders : a case-control study

2012

Objective: To compare the risk factors and clinical manifestations of patients with temporomandibular disorders (TMDs) diagnosed according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) (axis I) versus an age and gender matched control group. Study Design: A total of 162 patients explored according to the RDC/TMD (mean age 40.6±18.8 years, range 7-90; 11.1% males and 88.9% females) were compared with 119 controls, measuring differences in TMD risk factors (sleep disturbances, stress, psychoactive medication, parafunctions, loss of posterior support, ligament hyperlaxity) and clinical variables (joint sounds, painful muscle and joint palpation, maximum aperture…

AdultMalemedicine.medical_specialtyAdolescentPopulationResearch Diagnostic CriteriaPalpationYoung AdultRisk FactorsInternal medicinemedicineHumansMedical diagnosisYoung adultChildeducationGeneral DentistryAgedAged 80 and overeducation.field_of_studymedicine.diagnostic_testbusiness.industryMyofascial painCase-control studyMiddle AgedTemporomandibular Joint Disorders:CIENCIAS MÉDICAS [UNESCO]Orofacial Pain-TMJDmedicine.anatomical_structureOtorhinolaryngologyCase-Control StudiesUNESCO::CIENCIAS MÉDICASLigamentPhysical therapyResearch-ArticleFemaleSurgerybusiness
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The posterior talocalcaneal ligament: an MRI evaluation

2020

Purpose Awideinter-individualvariabilityintermsofsize,orientationandinsertionisobservedregardingankleligaments. The aim of this study is to identify and describe the anatomical features of the posterior talocalcaneal ligament (PTCL) observed through the use of magnetic resonance imaging (MRI) of the ankle. Methods The study was retrospectively carried out on 893 ankle MRI’s exams. The exams have all been performed using a 1.5-T (T) MRI. The same scanning protocols and scan planes were carried out in all the exams. The first evaluated param- eter was the recognition of the PTCL. Subsequently, in all those cases where the ligament was present, its features such as insertion sites, length, and…

AdultMalemedicine.medical_specialtyAdolescentPosterior talocalcaneal ligamentAnkle ligamentsPathology and Forensic MedicineYoung Adult03 medical and health sciencesAnkle ligaments Posterior talocalcaneal ligament Magnetic resonance imaging Ankle Anatomical variantmedicine.ligamentmedicineHumansRadiology Nuclear Medicine and imagingAgedRetrospective StudiesAged 80 and over0303 health sciencesmedicine.diagnostic_testbusiness.industryAnatomic VariationSubtalar JointMagnetic resonance imagingMiddle AgedMagnetic Resonance ImagingBiomechanical Phenomenamedicine.anatomical_structure030301 anatomy & morphologyLigaments ArticularOrthopedic surgeryLigamentFeasibility StudiesFemaleSurgeryAnkleAnatomyAnkleNuclear medicinebusinessSurgical and Radiologic Anatomy
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Corticosteroid injections, eccentric decline squat training and heavy slow resistance training in patellar tendinopathy.

2009

Udgivelsesdato: Sep-28 A randomized-controlled single-blind trial was conducted to investigate the clinical, structural and functional effects of peritendinous corticosteroid injections (CORT), eccentric decline squat training (ECC) and heavy slow resistance training (HSR) in patellar tendinopathy. Thirty-nine male patients were randomized to CORT, ECC or HSR for 12 weeks. We assessed function and symptoms (VISA-p questionnaire), tendon pain during activity (VAS), treatment satisfaction, tendon swelling, tendon vascularization, tendon mechanical properties and collagen crosslink properties. Assessments were made at 0 weeks, 12 weeks and at follow-up (half-year). All groups improved in VISA-…

AdultMalemedicine.medical_specialtyAdolescentmedicine.drug_classPhysical Therapy Sports Therapy and RehabilitationSquatlaw.inventionYoung AdultRandomized controlled triallawAdrenal Cortex HormonesPatellar LigamentSurveys and QuestionnairesCollagen networkMedicineEccentricHumansOrthopedics and Sports MedicineUltrasonographybusiness.industryResistance trainingResistance TrainingMiddle Agedmusculoskeletal systemTendonSurgerymedicine.anatomical_structureAnesthesiaTendinopathyCorticosteroidPatellar tendinopathybusinessScandinavian journal of medicinescience in sports
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Role of high-resolution ultrasonography without and with real-time spatial compound imaging in evaluating the injured posterior cruciate ligament: pr…

2009

This study sought to compare high-resolution ultrasonography (HRUS) without and with compound imaging in evaluating the injured posterior cruciate ligament (PCL). Thirteen patients with a magnetic resonance imaging (MRI) diagnosis of PCL lesions (ten acute and three chronic) and 20 healthy controls underwent conventional and compound HRUS performed by the same radiologist who was blinded to the subjects' case-control status. The PCL was scanned in a longitudinal direction in all cases. HRUS images were assessed for PCL thickness by two other radiologists blinded to the number and type of PCL injury. PCLs were classified as normal or injured, and the latter as having acute or chronic injurie…

AdultMalemedicine.medical_specialtyKnee InjuriesSeverity of Illness IndexmedicineImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingCompound imagingNeuroradiologyUltrasonographymedicine.diagnostic_testbusiness.industryUltrasoundReproducibility of ResultsPosterior cruciate ligament · Knee · Sonography · Real-time spatial compound sonography · Magnetic resonance imagingMagnetic resonance imagingInterventional radiologyGeneral Medicinemusculoskeletal systemMagnetic Resonance Imagingmedicine.anatomical_structurePosterior cruciate ligamentCase-Control StudiesHigh resolution ultrasonographyFemalePosterior Cruciate LigamentRadiologyUltrasonographybusinessLa Radiologia medica
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Cervical Spondylotic Myelopathy: When and Why the Cervical Corpectomy?

2020

Background: Cervical spondylotic myelopathy (CSM) is a degenerative disease that represents the most common spinal cord disorder in adults. The best treatment option has remained controversial. We performed a prospective study to evaluate the clinical, radiographic, and neurophysiologic outcomes for anterior cervical corpectomy in the treatment of CSM. Methods: From January 2011 to January 2017, 60 patients with CSM were prospectively enrolled in the present study. The patients were divided according to the modified Japanese Orthopaedic Association scale (mJOA) score into 2 groups: group A, patients with mild to moderate CSM (mJOA score ≥13); and group B, patients with severe myelopathy (mJ…

AdultMalemedicine.medical_specialtyRadiographymedicine.medical_treatmentSpinal Cord DisorderIntervertebral Disc DegenerationOssification of Posterior Longitudinal LigamentSeverity of Illness IndexMyelopathyYoung AdultDegenerative diseaseSpondylotic myelopathySymptom durationMedicineHumansProspective StudiesCorpectomyProspective cohort studyCervical corpectomy Young Adult Cervical spondylotic myelopathy Degenerative cervical myelopathy Surgical outcomes Adult Aged Cervical Vertebrae Decompression Surgical Functional Status Intervertebral Disc Degeneration Female Intervertebral Disc Displacement Humans Ossification of Posterior Longitudinal Ligament Middle Aged Male Prospective Studies Spinal Cord Compression Severity of Illness Index Treatment Outcome Spinal Fusion SpondylosisAgedbusiness.industryMiddle Agedmedicine.diseaseDecompression SurgicalSurgeryFunctional StatusSpinal FusionTreatment OutcomeCervical VertebraeSurgeryFemaleNeurology (clinical)SpondylosisbusinessSpinal Cord CompressionIntervertebral Disc DisplacementWorld neurosurgery
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Mechanical Properties of Human Patellar Tendon at the Hierarchical levels of Tendon and Fibril

2012

Tendons are strong hierarchical structures, but how tensile forces are transmitted between different levels remains incompletely understood. Collagen fibrils are thought to be primary determinants of whole tendon properties, and therefore we hypothesized that the whole human patellar tendon and its distinct collagen fibrils would display similar mechanical properties. Human patellar tendons ( n = 5) were mechanically tested in vivo by ultrasonography. Biopsies were obtained from each tendon, and individual collagen fibrils were dissected and tested mechanically by atomic force microscopy. The Young's modulus was 2.0 ± 0.5 GPa, and the toe region reached 3.3 ± 1.9% strain in whole patellar …

AdultMalemusculoskeletal diseasesMaterials sciencePhysiologymacromolecular substancesFibrilMicroscopy Atomic ForceCollagen fibrilPatellar LigamentPhysiology (medical)Elastic ModulusUltimate tensile strengthMicroscopymedicineHumansAtomic force microscopyta1182ta3141Anatomymusculoskeletal systemPatellar tendonTendonBiomechanical Phenomenamedicine.anatomical_structureCollagenStress Mechanical
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‘I was young, I wanted to return to sport, and re-ruptured my ACL’ – young active female patients’ voices on the experience of sustaining an ACL re-r…

2022

Abstract Background Despite anterior cruciate ligament (ACL) re-ruptures being common, research on patient experiences after knee trauma has primarily focused on the time after primary ACL reconstruction. Integrating qualitative research and patient experiences can facilitate researchers and clinicians in understanding the burden of an ACL re-rupture. The aim of the study was to explore the experiences of an ACL re-rupture journey in young active females aiming to return to knee-strenuous sports after primary ACL reconstruction. Method Fifteen young (19[range 16–23] years old) active females who suffered an ACL re-rupture were interviewed with semi-structured interviews. Qualitative content…

AdultRuptureAdolescentAnterior Cruciate Ligament ReconstructionAnterior Cruciate Ligament InjuriesReturn to SportVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Reumatologi: 759Young AdultRheumatologyHumansFemaleOrthopedics and Sports MedicineQualitative ResearchSportsBMC Musculoskeletal Disorders
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