Search results for "Ligand"

showing 9 items of 2559 documents

New Tetraphosphane Ligands {(X2P)2NC6H4N(PX2)2} (X = Cl, F, OMe, OC6H4OMe-o): Synthesis, Derivatization, Group 10 and 11 Metal Complexes and Catalyti…

2008

The reaction of p-phenylenediamine with excess PCl3 in the presence of pyridine affords p-C6H4[N(PCl2)2]2 (1) in good yield. Fluorination of 1 with SbF3 produces p-C6H4[N(PF2)2]2 (2). The aminotetra(phosphonites) p-C6H4[N{P(OC6H4OMe-o)2}2]2 (3) and p-C6H4[N{P(OMe)2}2]2 (4) have been prepared by reacting 1 with appropriate amount of 2-(methoxy)phenol or methanol, respectively, in the presence of triethylamine. The reactions of 3 and 4 with H2O2, elemental sulfur, or selenium afforded the tetrachalcogenides, p-C6H4[N{P(O)(OC6H4OMe-o)2}2]2 (5), p-C6H4[N{P(S)(OMe)2}2]2 (6), and p-C6H4[N{P(Se)(OMe)2}2]2 (7) in good yield. Reactions of 3 with [M(COD)Cl2] (M = Pd or Pt) (COD = cycloocta-1,5-diene)…

tetrafosfaaniliganditweak interactionsheikot vuorovaikutuksettetraphosphane ligandsDFT
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Tunable Interaction Strength and Nature of the S···Br Halogen Bonds in [(Thione)Br2] Systems

2015

The strength and nature of the S···Br and Br···Br interactions were systematically tuned by altering the electron donor properties of the thione group. Three new halogen-bonded compounds, [(N-methylbenzothiazole-2-thione)Br2]·0.5CH2Cl2 (1), [(2(3H)-benzothiazolethione)Br2] (2), and [(2-benzimidazolethione)Br]·[Br3] (3), were synthesized and studied structurally by using X-ray crystallography and computationally by using charge density analysis based on QTAIM calculations. Analysis of the interaction strength indicated a formation of surprisingly strong S···Br halogen bonds in 1 (−104 kJ mol–1, and RBrS = 0.64) and 2 (−116 kJ mol–1, and RBrS = 0.63) with a substantial covalent contribution. …

thionessynthesis010405 organic chemistryChemistryLigandStereochemistryCharge densityElectron donorGeneral ChemistryInteraction energy010402 general chemistryCondensed Matter Physics01 natural sciencesHeterolysis0104 chemical sciences3. Good healthCrystallographychemistry.chemical_compoundhalogen bondingCovalent bondHalogenMoleculeGeneral Materials Scienceta116bromideCrystal Growth & Design
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Effect of ligand-binding on protein function

2014

tietokonesimulointifilamiinitliganditsitoutuminenionotrooppiset glutamaattireseptoritfilaminpeptidiliganditmolecular dynamicsionotropic glutamate receptorlääkesuunnitteluFLNaiGluRlaskennallinen tiedelaskennalliset menetelmätmolekyylidynamiikkaTCPTPsimulointiproteiinitbinding free energyT-cell protein tyrosine phosphatase
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Alkyl-Substituted Aminobis(phosphonates) : Efficient Precipitating Agents for Rare Earth Elements, Thorium, and Uranium in Aqueous Solutions

2021

The efficient and environmentally sustainable separation process for rare earth elements (REE), especially for adjacent lanthanoids, remains a challenge due to the chemical similarity of REEs. Tetravalent actinoids, thorium, and traces of uranium are also present in concentrates of REEs, making their separation relevant. This study reports six simple water-soluble aminobis(phosphonate) ligands, RN[CH2P(O)(OH)2]2 (1 R = CH2CH3, 2 R = (CH2)2CH3, 3 R = (CH2)3CH3, 4 R = (CH2)4CH3, 5 R = (CH2)5CH3, 6 R = CH2CH(C2H5)(CH2)3CH3) as precipitating agents for REEs, Th, and U, as well as gives insight into the coordination modes of the utilized ligands with REEs at the molecular level. Aminobis(phospho…

titrationsaostusligandsmetalslanthanidestitrausliganditprecipitationmetallit
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Nuevos ligandos polinitrogenados derivados de [1,2,3]triazolo[1,5-a]piridinas. Caracterización y estudio de sus potenciales aplicaciones

2016

El presente trabajo de tesis doctoral se compone de seis capítulos. El primer y segundo capítulo son de carácter introductorio donde se exponen los objetivos de la investigación y los antecedentes bibliográficos. En los siguientes tres capítulos se exponen tres diferentes tipos de funcionalización del anillo triazolopiridínico mientras que en el último capítulo se presentan los estudios de propiedades ópticas de algunos derivados descritos en el quinto capítulo. La primera parte del trabajo, que se describe en el capítulo 3, ha sido el estudio de la reactividad del anillo triazolopiridínico en condiciones de arilación directa. La [1,2,3]triazolo[1,5-a]piridina reacciona con halogenuros arom…

triazolopiridinasUNESCO::QUÍMICAligandos polinitrogenados:QUÍMICA [UNESCO]
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Dioxomolybdenum(VI) and -Tungsten(VI) Amino Bisphenolates as Epoxidation Catalysts

2016

Low-cost metallate salts Na2MO4·2H2O (M = molybdenum, tungsten) react with a tridentate amine bisphenol bis(2-hydroxy-3-tert-butyl-5-methylbenzyl)methylamine (H2ONOtBu) under ambient conditions in acidic methanol solutions. The reactions lead to the formation of isostructural dioxo complexes [MO2(ONOtBu)(MeOH)]·MeOH in convenient yields. Spectral data as well as X-ray analyses reveal these complexes to be isostructural. Both compounds were tested as catalysts for epoxidation of olefins using cis-cyclooctene, cyclohexene, norbornene and styrene as substrates and tert-butyl hydroperoxide and hydrogen peroxide as oxidants. The molybdenum complex catalyses selectively the oxidation of cis-cyclo…

tridentate ligands010405 organic chemistryCyclohexenemolybdenum complexesGeneral Chemistry010402 general chemistry01 natural sciencesCatalysis0104 chemical sciencesStyreneCatalysischemistry.chemical_compoundMetallatechemistryBenzoinkatalyysiepoxidationPolymer chemistryOrganic chemistryBenzilIsostructuraltungsten complexesNorborneneTopics in Catalysis
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An experimental and theoretical study of a heptacoordinated tungsten(VI) complex of a noninnocent phenylenediamine bis(phenolate) ligand

2018

Abstract [W(N2O2)(HN2O2)] (H4N2O2 = N,N′-bis(3,5-di-tert-butyl-2-hydroxyphenyl)-1,2-phenylenediamine) with a noninnocent ligand was formed by reaction of the alkoxide precursor [W(eg)3] (eg = the 1,2-ethanediolate dianion) with two equivalents of ligand. The phenol groups on one of the ligands are completely deprotonated and the ligand coordinates in a tetradentate fashion, whereas the other ligand is tridentate with one phenol having an intact OH group. The molecular structure, magnetic measurements, EPR spectroscopy, and density functional theory calculations indicate that the complex is a stable radical with the odd electron situated on the tridentate amidophenoxide ligand. The formal ox…

tungstenDFT calculations010402 general chemistry01 natural scienceslaw.inventionInorganic Chemistrychemistry.chemical_compoundDeprotonationlawOxidation stateMaterials ChemistryMoleculePhysical and Theoretical ChemistryElectron paramagnetic resonanceta116amidophenoxide radical010405 organic chemistryLigandkompleksiyhdisteetvolframielectronic structure0104 chemical sciencesCrystallographyoxidation statesUnpaired electronchemistryAlkoxidenoninnocent ligandDensity functional theoryInorganic Chemistry Communications
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Rational drug discovery : structural studies of protein-ligand complexes

2011

vaskulaarinen adheesioproteiini 1rational drug discoveryrationaalinen lääkeainesuunnitteluVAP-1hydrazinefilamiinitfilaminvascular adhesion protein 1ligandinsitomistaskutmolecular dynamicsligand binding pocketshydratsiinimolekyylidynamiikkaTCPTPCFTR
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Discovery of α2β1 integrin ligands : tools and drug candidates for cancer and thrombus

2011

α2β1-integriiniliganditintegriinitintegriinisalpaajatα2β1 integrinthrombusrational drug discoverysyöpäkollageenitliganditveritulppacollagen receptor integrinsfarmakoforitX-ray crystallography
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