Search results for "Light"

showing 10 items of 3575 documents

Spectral Transmission of the Human Crystalline Lens in Adult and Elderly Persons: Color and Total Transmission of Visible Light

2012

Purpose To experimentally measure the spectral transmission of human crystalline lenses belonging to adult and elderly persons, and to determine the color and total transmission of visible light of such crystalline lenses. Methods The spectral transmission curve of 32 human crystalline lenses was measured using a PerkinElmer 800UV/VIS spectrometer. Total transmission of visible light and the chromatic coordinates of these crystalline lenses were determined from these curves for solar illumination. Results The crystalline lens that filters UV and its transmission in the visible spectrum decreases with age; such a decrease is greater for short wavelengths. The total transmission of visible li…

AdultMaleAgingMaterials scienceUltraviolet RaysColorMineralogylaw.inventionOpticsElderly personslawLens CrystallineTransmittanceHumansChromatic scaleAgedSunlightSpectrometerbusiness.industrySpectrum AnalysisMiddle Agedeye diseasesLens (optics)WavelengthSunlightFemalesense organsbusinessPhotic StimulationVisible spectrumInvestigative Opthalmology & Visual Science
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Reproducibility of optical biometry using partial coherence interferometry: intraobserver and interobserver reliability

2001

Abstract Purpose: To evaluate the intraobserver and interobserver variability in axial length (AL), anterior chamber depth (ACD), and corneal radius measurements using an optical biometry instrument based on partial coherence interferometry (PCI). Setting: Johannes Gutenberg University, Mainz, Germany. Methods: In this observational case series and interobserver reliability trial, 30 healthy, emmetropic to moderately myopic eyes of 15 volunteers were evaluated. The AL, ACD, and corneal radius were measured 20 times in 10 eyes by 1 observer to evaluate the intraobserver variability. To evaluate the interobserver variability, the measurements were taken in 20 eyes by 5 different observers. Me…

AdultMaleBiometryLightInterobserver reliabilityAnterior ChamberEmmetropiaData descriptionCorneaOptical biometryOpticsMyopiaHumansReliability (statistics)AgedMathematicsObserver VariationReproducibilitybusiness.industryCorneal TopographyReproducibility of ResultsMiddle AgedSensory SystemsOphthalmologyInterferometryPartial coherence interferometryFemaleSurgerybusinessNuclear medicinePartial coherenceJournal of Cataract and Refractive Surgery
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In Lysinuric Protein Intolerance system y+L activity is defective in monocytes and in GM-CSF-differentiated macrophages

2010

Abstract Background In the recessive aminoaciduria Lysinuric Protein Intolerance (LPI), mutations of SLC7A7/y+LAT1 impair system y+L transport activity for cationic amino acids. A severe complication of LPI is a form of Pulmonary Alveolar Proteinosis (PAP), in which alveolar spaces are filled with lipoproteinaceous material because of the impaired surfactant clearance by resident macrophages. The pathogenesis of LPI-associated PAP remains still obscure. The present study investigates for the first time the expression and function of y+LAT1 in monocytes and macrophages isolated from a patient affected by LPI-associated PAP. A comparison with mesenchymal cells from the same subject has been a…

AdultMaleCellular differentiationlcsh:MedicinePulmonary Alveolar ProteinosisBiologyMonocytesPathogenesisYoung AdultMacrophages AlveolarmedicineHumansGenetics(clinical)Pharmacology (medical)Amino Acid Metabolism Inborn ErrorsCells CulturedGenetics (clinical)Medicine(all)chemistry.chemical_classificationResearchFusion Regulatory Protein 1 Light ChainsLysinelcsh:RMesenchymal stem cellAmino Acid Transport System y+LGranulocyte-Macrophage Colony-Stimulating FactorCell DifferentiationGeneral Medicinemedicine.diseaseLysinuric protein intoleranceMolecular biologyAmino acidGranulocyte macrophage colony-stimulating factorchemistryAminoaciduriaImmunologyPulmonary alveolar proteinosismedicine.drugOrphanet Journal of Rare Diseases
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The effects of post-awakening light exposure on the cortisol awakening response in healthy male individuals.

2019

Abstract Background It is assumed that the expression of the cortisol awakening response (CAR) is modulated by light exposure during the peri-awakening period. While initial evidence supports this principal effect, the specific role of the spectral composition of light (brightness and wavelength) is still incompletely understood. Method Two counterbalanced within-subject experiments were conducted in a standardized sleep laboratory setting to investigate the effect of light intensity (study I; two days: dim vs. bright light) and spectral composition (study II; three days: red vs. blue vs. green light) on the CAR. Across studies, light exposure was conducted for one-hour post-awakening and t…

AdultMaleCortisol awakening responseHydrocortisoneLightEndocrinology Diabetes and MetabolismPhysiology03 medical and health sciencesYoung Adult0302 clinical medicineEndocrinologyMedicineHumansWakefulnessSalivaBiological PsychiatrySpectral compositionLight exposureEndocrine and Autonomic Systemsbusiness.industrySleep laboratoryPhototherapyHealthy Volunteers030227 psychiatryCircadian RhythmPsychiatry and Mental healthLight intensitybusinessSleep030217 neurology & neurosurgeryBright lightPsychoneuroendocrinology
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Colour Constancy in Goldfish and Man: Influence of Surround Size and Lightness

2002

Colour constancy was investigated by using a series of 10 simultaneously presented surface colours ranging in small steps from green through gray to red – purple. Goldfish were trained to select one medium test field when the entire setup was illuminated with white light. In the tests, either red or green illumination was used. Colour constancy, as inferred from the choice behaviour, was perfect under green illumination when the test fields were presented on a gray or a white background, but imperfect on a black background. Under red illumination and a white background, however, colour constancy was overcompensated. Here, a colour contrast effect was observed. The influence of background l…

AdultMaleExperimental and Cognitive PsychologyLuminance050105 experimental psychologyContrast Sensitivity03 medical and health sciences0302 clinical medicineOpticsArtificial IntelligenceGoldfishPsychophysicsCarassius auratusWhite lightAnimalsHumans0501 psychology and cognitive sciencesMathematicsColor constancybusiness.industry05 social sciencesSensory SystemsOphthalmologyFemaleColour contrastbusinessColor PerceptionPhotic Stimulation030217 neurology & neurosurgeryPerception
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Clinical efficacy of semiconductor laser application as an adjunct to conventional scaling and root planing.

2005

Background and Objectives: The aim of the in vitro study was to examine the clinical efficacy of semiconductor laser periodontal pocket irradiation as an adjunct to conventional scaling and root planing. Materials and Methods: Twenty-two healthy patients with a need of periodontal treatment (15 women, 7 men, mean age 45.0� 10.8 years) with at least four teeth in all quadrants, were included. All of them underwent a conventional periodontal treatment including scaling and root planing. Using a split mouth design, two randomly chosen quadrants (one upper and the corresponding lower one) were subsequently treated with an 809 nm GaAlAs laser operated at a power output of 1.0 Watt using a 0.6 mm…

AdultMaleGingival and periodontal pocketmedicine.medical_treatmentBleeding on probingDentistryDermatologySensitivity and SpecificityStatistics NonparametricRoot PlaningTooth mobilityScaling and root planingMedicineHumansPeriodontal PocketProspective StudiesLow-Level Light TherapyProspective cohort studySalineProbabilityPeriodontitisbusiness.industryMiddle Agedmedicine.diseaseCombined Modality TherapyTreatment OutcomeClinical attachment lossCase-Control StudiesDental ScalingSurgeryFemalemedicine.symptombusinessFollow-Up StudiesLasers in surgery and medicine
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Sensorimotor adaptation of point-to-point arm movements after spaceflight: the role of internal representation of gravity force in trajectory plannin…

2011

International audience; After an exposure to weightlessness, the central nervous system operates under new dynamic and sensory contexts. To find optimal solutions for rapid adaptation, cosmonauts have to decide whether parameters from the world or their body have changed and to estimate their properties. Here, we investigated sensorimotor adaptation after a spaceflight of 10 days. Five cosmonauts performed forward point-to-point arm movements in the sagittal plane 40 days before and 24 and 72 h after the spaceflight. We found that, whereas the shape of hand velocity profiles remained unaffected after the spaceflight, hand path curvature significantly increased 1 day after landing and return…

AdultMaleGravity (chemistry)Physiologymedia_common.quotation_subjectMovementKinematicsInertiaSpaceflightlaw.invention03 medical and health sciences0302 clinical medicineControl theorylawmedicineHumans030304 developmental biologymedia_commonMathematics0303 health sciencesCommunicationHypergravitybusiness.industryWeightlessnessWeightlessnessGeneral Neuroscience[SCCO.NEUR]Cognitive science/NeuroscienceMotor controlMiddle AgedSpace FlightAdaptation PhysiologicalSagittal planemedicine.anatomical_structure[ SCCO.NEUR ] Cognitive science/NeuroscienceArmAstronautsFemalebusiness030217 neurology & neurosurgeryPsychomotor PerformanceGravitation
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Influence of stimulus color on the control of reaching-grasping movements.

2001

This kinematic study aimed to determine whether color is a stimulus property involved in the control of reaching-grasping movements. Subjects reached and grasped a target-object, located either on the right or on the left of the subject's midline. A distractor, placed along the subject's midline, could be randomly presented. The colors, i.e., both chromaticity (red and green stimuli were presented) and lightness, of the target and distractor were varied in experiment 1. Only stimulus lightness and only stimulus chromaticity were varied in experiments 2 and 3, respectively. In experiment 4 subjects matched with their thumb and index finger the size of the target-stimuli presented in experime…

AdultMaleHuman kinematicsProperty (programming)MovementKinematicsStimulus (physiology)Neuropsychological TestsTarget colorOpticsOrientationmedicineReaction TimeHumansComputer visionChromaticity and lightnessChromaticityHand Strengthbusiness.industryGeneral NeuroscienceGRASPMotor controlReaching-graspingBody movementIndex fingerBiomechanical Phenomenamedicine.anatomical_structurePattern Recognition VisualSpace PerceptionArmFemaleArtificial intelligencebusinessPsychologyInterferenceReaching-grasping · Human kinematics · Target color · Chromaticity and lightness · InterferenceColor PerceptionPhotic StimulationPsychomotor PerformanceExperimental brain research
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The effects of light exposure on the cortisol stress response in human males.

2020

It is assumed that the production of cortisol is modulated by light exposure. While initial evidence supports this principal effect, the specific effect of light (intensity and wavelength) onto the cortisol stress response is still not completely understood. One between-subject experiment was conducted in a standardized sleep laboratory setting to investigate the effect of light intensity (dim white vs. bright white light) and spectral composition (red vs. blue) on the cortisol response after the Maastricht Acute Stress Test (MAST). 112 healthy young males (24.83 ± 4.10 years of age) were randomly assigned to one of the four light conditions. Across conditions, light exposure was conducted …

AdultMaleHydrocortisonePhysiologyHuman MalesFight-or-flight responseStress (mechanics)03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineHumansSalivaLight exposureMelatoninEndocrine and Autonomic SystemsChemistry030227 psychiatryIntensity (physics)Circadian RhythmPsychiatry and Mental healthLight intensityWavelengthNeuropsychology and Physiological PsychologyBiophysics030217 neurology & neurosurgeryStress PsychologicalStress (Amsterdam, Netherlands)
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Comparison of Cortisol Stress Response in Patients with Panic Disorder, Cannabis-Induced Panic Disorder, and Healthy Controls

2018

<b><i>Background/Aims:</i></b> Little research effort has so far been dedicated to the analysis of the hypothalamic-pituitary-adrenal axis of aetiologically differing subgroups of patients with panic disorder (PD). The current study aimed at a deeper understanding of the cortisol stress response in cannabis-induced PD (CIPD) patients. <b><i>Methods:</i></b> Matched groups of 7 PD patients (mean age ± SD: 32.95 ± 9.04 years), 7 CIPD patients (31.94 ± 8.40 years), and 7 healthy controls (HC) (31.13 ± 8.57 years) were included in the study. The Trier Social Stress Test (TSST) was used for stress induction. Salivary cortisol samples were collected…

AdultMaleHypothalamo-Hypophyseal Systemendocrine systemmedicine.medical_specialtyHydrocortisoneSubstance-Related DisordersGastroenterologyFight-or-flight response03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesInternal medicinemedicineTrier social stress testHumansIn patientSalivaCannabisbiologyPanic disorderPanicbiology.organism_classificationmedicine.disease030227 psychiatryPsychiatry and Mental healthClinical Psychologymedicine.anatomical_structurePanic DisorderFemaleCannabismedicine.symptomPsychologyStress Psychological030217 neurology & neurosurgeryHypothalamic–pituitary–adrenal axisHormonal responsePsychopathology
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