Search results for "Ligo"
showing 10 items of 1427 documents
Role of repulsive interaction on the fibrillogenesis of hen egg-white lysozyme
2010
Fibrillogenesis of hen egg-white lysozyme at acidic pH
2009
Role of electrostatic interactions in the fibrillogenesis of lysozyme
2011
(E)-2-cyano-3-(5'-piperidin-1-yl-2,2'-bithien-5-yl)acrylic acid: a new fluorescent probe for detecting prefibrillar oligomers
2013
Modular Small Diameter Vascular Grafts with Bioactive Functionalities.
2015
We report the fabrication of a novel type of artificial small diameter blood vessels, termed biomimetic tissue-engineered blood vessels (bTEBV), with a modular composition. They are composed of a hydrogel scaffold consisting of two negatively charged natural polymers, alginate and a modified chitosan, N,O-carboxymethyl chitosan (N,O-CMC). Into this biologically inert scaffold two biofunctionally active biopolymers are embedded, inorganic polyphosphate (polyP) and silica, as well as gelatin which exposes the cell recognition signal, Arg-Gly-Asp (RGD). These materials can be hardened by exposure to Ca(2+) through formation of Ca(2+) bridges between the polyanions, alginate, N,O-CMC, and polyP…
Spent Coffee Grounds Extract, Rich in Mannooligosaccharides, Promotes a Healthier Gut Microbial Community in a Dose-Dependent Manner.
2019
Coffee is one of the most consumed beverages around the world, and as a consequence, spent coffee grounds are a massively produced residue that is causing environmental problems. Reusing them is a major focus of interest presently. We extracted mannooligosaccharides (MOS) from spent coffee grounds and submitted them to an in vitro fermentation with human feces. Results obtained suggest that MOS are able to exert a prebiotic effect on gut microbiota by stimulating the growth of some beneficial genera, such as Barnesiella, Odoribacter, Coprococcus, Butyricicoccus, Intestinimonas, Pseudoflavonifractor, and Veillonella. Moreover, short-chain fatty acids (SCFA) production also increased in a dos…
Global-Scale Environmental Niche and Habitat of Blue Shark (Prionace glauca) by Size and Sex: A Pivotal Step to Improving Stock Management
2022
25 pages, 10 figures, 2 tables, supplementary material https://www.frontiersin.org/articles/10.3389/fmars.2022.828412/full#supplementary-material.-- Data Availability Statement: The blue shark habitat data are available on the JRC Data Catalogue (https://data.jrc.ec.europa.eu/dataset?q=fish%20habitat) (or upon request) and habitat maps are available online (https://fishreg.jrc.ec.europa.eu/web/fish-habitat/habitatmapping). Chlorophyll-a data are available online (https://oceancolor.gsfc.nasa.gov/cgi/l3). The abiotic environmental and mesopelagic micronekton data are available online (https://marine.copernicus.eu/access-data).
Efficient stabilisation of a dihydrogenphosphate tetramer and a dihydrogenpyrophosphate dimer by a cyclic pseudopeptide containing 1,4-disubstituted …
2017
A cyclic pseudooctapeptide 2 is described containing 1,4-disubstituted 1,2,3-triazole moieties. This compound features eight converging hydrogen bond donors along the ring, namely four amide NH and four triazole CH groups, which enable 2 to engage in interactions with anions. While fully deprotonated sulfate anions exhibit only moderate affinity for 2, protonated anions such as dihydrogenpyrophosphate and dihydrogenphosphate anions are strongly bound. Complexation of the phosphate-derived anions involves sandwiching of a dihydrogenpyrophosphate dimer or a dihydrogenphosphate tetramer between two pseudopeptide rings. X-ray crystallography provided structural information, while 1H NMR spectro…
Study of Thermotoga maritima ß-galactosidase: immobilization, engineering and phylogenetic analysis
2016
La actividad de las lactasas fue descrita por Beijerink en 1889. El origen de dicha actividad era la ß-galactosidasa de la levadura Kluyveromyces lactis capaz de hidrolizar la lactosa en sus dos componentes, galactosa y glucosa. En la actualidad las ß-galactosidasas tienen dos aplicaciones principales, por un lado se utilizan para la obtención de productos libres en lactosa y por otro lado para la síntesis de galactooligosacáridos (GOS), a algunos de los cuales se les han asociado propiedades prebióticas. Esta doble capacidad de la enzima se da gracias al mecanismo de retención que comparte con otras proteínas del clan GH-A en la clasificación del CAZy.En este trabajo hemos explorado la pos…
Sinbiotiska produkta iegūšana, veicot no piena permeāta iegūta galaktooligosaharīdu (GOS) maisījuma selektīvu fermentāciju ar probiotiskiem celmiem
2022
Piena permeāts un tajā esošā laktoze kā substrāts var tikt izmantots ogļhidrātu biokonversijas pētījumos, kā arī dažādu mikroorganismu kultivēšanā, lai veidotu produktus ar pievienoto vērtību. Darba mērķis bija izvērtēt iespēju iegūt galaktooligosaharīdu (GOS) un pienskābo baktēriju saturošu sinbiotisku produktu, veicot selektīvu fermentāciju maisījumā, kas iegūts fermentatīvās GOS biosintēzes laikā no piena permeāta. Veicot fermentatīvu sintēzi ar ß-galaktozidāzēm, tika iegūts un aprakstīts GOS saturošs maisījums, kurā vēlāk tika veikta selektīva fermentācija ar probiotiskajiem Lactobacillus spp. celmiem, izvērtējot šo celmu ogļhidrātu preferences un izdzīvotību. Veicot fermentatīvu sintēz…