Search results for "Limite"

Bayesian pharmacokinetic-guided prophylaxis with recombinant factor VIII in severe or moderate haemophilia A

2018

Introduction: Personalised pharmacokinetics (PK) using Bayesian analysis with limited sampling is assumed to help to optimise prophylaxis in haemophilia A (HA) patients. Materials and methods: Our prospective, observational study analysed the influence of PK parameters on clinical variables (bleeding rates, joint status, adherence, and consumption) using myPKFiT (R) in a cohort of twenty-one severe and moderate HA patients on prophylaxis with recombinant FVIII (Advate (R)) in two periods of one year, the first before PK-based tailoring and the second after PK-guided prophylaxis. Intra-individual and inter-individual coefficients of variation (CV) of half-life (t(1/2)) were calculated. Resul…

2019 revised algorithm for the management of knee osteoarthritis: the Southeast Asian viewpoint

2021

Abstract Background Since 2014, the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) algorithm for the management of knee osteoarthritis (OA) is available worldwide. Aim Based on this document, a Southeast Asia Working Group (SEAWG) wished to see how the new ESCEO algorithm developed in 2019 was perceived by Southeast Asian experts and how it was integrated into their clinical practice. Methods A SEAWG was set up between members of the international ESCEO task force and a group of Southeast Asian experts. Results Non-pharmacological management should always be combined with pharmacological management. In step 1, symptoma…

Costruzioni in zone sismiche - progetto e verifica a presso-flessione agli stati limite ultimi.

2004

L'étendue de l'obligation de curiosité des parties sur l'indépendance

2020

International audience; (Civ. 1re, 3 oct. 2019, n° Y 18-15.756, Sté Audi Volkswagen Middle East Fze LLC c/ Sté Saad BuzwairAutomotive Co, inédit)

Précisions sur la responsabilité du gérant SARL à l'égard des associés

2013

International audience; Note sous Cour de cassation (com.) 10 juillet 2012, F-D, n° 11-22.146, Ferhat c/ Nemmar

Spectral Structures in Econometrics: Modern Techniques in Wavelet Analysis and Band Limited Estimation

2007

This thesis presents a number of innovative techniques that can be used in the analysis of econometric data sequences in which the underlying components can be identified by their spectral signatures. To present these techniques intelligibly requires the preparatory expositions of Fourier analysis and of the theory of linear filtering that are presented in Chapters 2 and 3. Amongst the techniques for extracting components from short non stationary sequences that are described in Chapter 3 is a variant of the Hodrick--Prescott filter with a smoothing parameter that varies locally. This enables us to extract from the data trends that incorporate a number of structural breaks. The inadequacy o…

Non-Dyadic Wavelet Analysis

2006

The conventional dyadic multiresolution analysis constructs a succession of frequency intervals in the form of $(\pi/2^j, \pi/2^{j-1});j = 1, 2, \ldots, n$ of which the bandwidths are halved repeatedly in the descent from high frequencies to low frequencies. Whereas this scheme provides an excellent framework for encoding and transmitting signals with a high degree of data compression, it is less appropriate to the purposes of statistical data analysis. This paper describes a non-dyadic mixed-radix wavelet analysis which allows the wave bands to be defined more flexibly than in the case of a conventional dyadic analysis. The wavelets that form the basis vectors for the wave bands are derive…

Diagnostic yield of a one sample immunochemical test at different cut-off values in an organised screening programme for colorectal cancer

2013

Abstract Background Quantitative immunochemical faecal occult blood tests have become the recommended tests for colorectal cancer screening. The aim of this study was to complete our knowledge on the performance of one of the quantitative immunochemical tests available, FOB-Gold, and to propose a possible strategy for an organised screening programme. Patients and methods Within the French organised screening programme, 23,231 average-risk individuals, aged 50–74 performed both a 3-day Hemoccult test and a 1-day FOB-Gold test. Performances of the immunochemical test were evaluated at different cut-off levels. Results The positivity rate for the Hemoccult was 2.1% and for the FOB-Gold varied…

Nullité facultative d'une saisie-attribution diligentée en période suspecte par un créancier social sur la fraction non libérée du capital social. Fa…

2017

International audience; (Civ. 2e, 12 mai 2016, n° 15-13.833, F-P+B, Sté Yara c/ Fondation Institut du Monde Arabe, D. 2016. 1088 ; Rev. sociétés 2016. 673, note A. Lecourt ; Bull. Joly 2016. 588, note F. Danos ; Act. proc. coll. 2016, comm. 158, obs. J.-M. Moulin)

Analysis of health communication texts: UK press coverage of debates about assisted dying

2015

Conventionally, social researchers analyse media messages by reading text and coding it. This is time consuming and restricts many studies to small samples. Nowadays very large amounts of text are available in electronic form, offering potential insights into the health messages they contain, but which appear daunting to the analyst with limited resources using conventional methods. I explain and illustrate methods for the computer-assisted analysis of media texts, using specialised software (Wordsmith Tools and Wordstat). These allow the analyst to provide a statistical overview of the key features of texts, to compare them (looking at change over time, for example) and to select illustrat…