Search results for "Linear Regression Analysis"

showing 10 items of 40 documents

Structural invariants for the prediction of relative toxicities of polychloro dibenzo-p-dioxins and dibenzofurans

2004

Multivariate models are reported that can predict the relative toxicity of compounds with severe environmental impact, namely polychloro dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). Multiple linear regression analysis (MLR) and partial least square projections of latent variables (PLS) show the usefulness of graph-theoretical descriptors, mainly topological charge indices (TCIs), in these series. The general trends of the group are correctly reproduced and better results are presented than have previously been published. In general, the more toxic compounds exhibit more symmetric molecular structures.

Multivariate statisticsCarcinoma HepatocellularPolychlorinated DibenzodioxinsRelative toxicityQuantitative Structure-Activity RelationshipLatent variableDioxinsCatalysisInorganic ChemistryToxicologyComputational chemistryDrug DiscoveryLinear regressionCytochrome P-450 CYP1A1AnimalsSoil PollutantsLeast-Squares AnalysisPhysical and Theoretical ChemistryMolecular BiologyBenzofuransModels StatisticalChemistryOrganic ChemistryReproducibility of Resultsfood and beveragesNeoplasms ExperimentalGeneral MedicineModels TheoreticalRatsDisease Models AnimalModels ChemicalDrug DesignMultivariate AnalysisLinear ModelsEnvironmental PollutantsMultiple linear regression analysisInformation SystemsMolecular Diversity
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Association of Common Polymorphisms in the Nicotinic Acetylcholine Receptor Alpha4 Subunit Gene with an Electrophysiological Endophenotype in a Large…

2016

PLoS one 11(4), e0152984 (2016). doi:10.1371/journal.pone.0152984

Male0301 basic medicineNicotinic Acetylcholine ReceptorsPhysiologyEvent-Related Potentialslcsh:MedicineReceptors NicotinicElectroencephalography600 Technik Medizin angewandte Wissenschaften::610 Medizin und GesundheitBiochemistryExonCognitionMathematical and Statistical Techniques0302 clinical medicineMedizinische FakultätGermanyMedicine and Health Scienceslcsh:ScienceCerebral CortexClinical NeurophysiologyGeneticsBrain MappingN100education.field_of_studyMultidisciplinarymedicine.diagnostic_testSmokingBrainElectroencephalographyTobacco Use DisorderTemporal LobeFrontal LobeElectrophysiologyNicotinic acetylcholine receptorBioassays and Physiological AnalysisBrain ElectrophysiologyPhysical SciencesRegression AnalysisFemaleAnatomyFunction and Dysfunction of the Nervous SystemStatistics (Mathematics)Research ArticleSignal TransductionAdultTransmembrane ReceptorsImaging TechniquesEndophenotypesCognitive NeurosciencePopulation610NeurophysiologyNeuroimagingSingle-nucleotide polymorphism-Linear Regression AnalysisBiologyResearch and Analysis MethodsPolymorphism Single Nucleotide03 medical and health sciencesDiagnostic MedicineEvent-related potentialReaction TimemedicineHumansddc:610Statistical MethodseducationElectrophysiological Techniqueslcsh:RBiology and Life SciencesProteinsCell BiologyElectrophysiological Phenomena030104 developmental biologyAcetylcholine ReceptorsEndophenotypeCognitive Sciencelcsh:QMathematics030217 neurology & neurosurgeryNeuroscience
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Training at maximal power in resisted sprinting: Optimal load determination methodology and pilot results in team sport athletes.

2018

Aims: In the current study we investigated the effects of resisted sprint training on sprinting performance and underlying mechanical parameters (force-velocity-power profile) based on two different training protocols: (i) loads that represented maximum power output (Lopt) and a 50% decrease in maximum unresisted sprinting velocity and (ii) lighter loads that represented a 10% decrease in maximum unresisted sprinting velocity, as drawn from previous research (L10). Methods: Soccer [n = 15 male] and rugby [n = 21; 9 male and 12 female] club-level athletes were individually assessed for horizontal force-velocity and load-velocity profiles using a battery of resisted sprints, sled or robotic r…

AdultMalevelocityhuman performancePhysiology[SDV]Life Sciences [q-bio]educationlcsh:MedicinePilot ProjectsAthletic PerformanceResearch and Analysis MethodsRemote SensingWeight-BearingMotionMathematical and Statistical TechniquesMedicine and Health SciencesrunningHumansStatistical Methodslcsh:ScienceroboticsBehaviorBiological LocomotionPhysicsMechanical Engineeringlcsh:RBiology and Life SciencesClassical MechanicsResistance TrainingaccelerationSports ScienceAthletesPhysical Scienceslinear regression analysisRecreationRegression AnalysisEngineering and TechnologyFemalelcsh:Qsportshuman activitiesMathematicsStatistics (Mathematics)Research ArticleradarPLoS ONE
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Dentin degradonomics – The potential role of salivary MMP-8 in dentin caries

2019

Background Dentin caries involves dissolution of minerals which eventually leads to degradation of organic matrix. This degradation which was thought to be by bacterial proteases is now considered to be orchestrated by endogenous collagenases such as Matrix Metalloproteinases (MMPs). This paper aims to estimate the salivary levels of MMP-8 in dental caries and also to asses the various risk factors that contribute to the formation of dental caries. Material and methods A random sample of 75 adults aged 18-35 were included and categorized based on the number of caries lesions (MCL). Standard clinical examinations were performed, and stimulated saliva was collected and analyzed for concentrat…

medicine.medical_specialtySalivaOral Medicine and Pathologybusiness.industryResearch030206 dentistryMatrix metalloproteinase:CIENCIAS MÉDICAS [UNESCO]Positive correlationGastroenterology03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureInternal medicineUNESCO::CIENCIAS MÉDICASDentinmedicineOrganic matrixMultiple linear regression analysis030212 general & internal medicineDentin cariesbusinessGeneral DentistryJournal of Clinical and Experimental Dentistry
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Optimizing colormaps with consideration for color vision deficiency to enable accurate interpretation of scientific data

2018

Color vision deficiency (CVD) affects more than 4% of the population and leads to a different visual perception of colors. Though this has been known for decades, colormaps with many colors across the visual spectra are often used to represent data, leading to the potential for misinterpretation or difficulty with interpretation by someone with this deficiency. Until the creation of the module presented here, there were no colormaps mathematically optimized for CVD using modern color appearance models. While there have been some attempts to make aesthetically pleasing or subjectively tolerable colormaps for those with CVD, our goal was to make optimized colormaps for the most accurate perce…

FOS: Computer and information sciences0301 basic medicineBrightnessVisual perceptionVisionComputer scienceComputer Vision and Pattern Recognition (cs.CV)Computer Science - Computer Vision and Pattern Recognitionlcsh:MedicineSocial SciencesColor Vision Defects01 natural sciencesMass SpectrometryAnalytical ChemistrySecondary Ion Mass SpectrometrySpectrum Analysis TechniquesMathematical and Statistical TechniquesPsychologyComputer visionlcsh:ScienceData ProcessingMultidisciplinaryPhysicsClassical MechanicsOther Quantitative Biology (q-bio.OT)Quantitative Biology - Other Quantitative BiologyChemistryPhysical SciencesRegression AnalysisSensory PerceptionInformation TechnologyStatistics (Mathematics)AlgorithmsColor PerceptionResearch ArticleComputer and Information SciencesColor visionColorFluid MechanicsLinear Regression AnalysisColor spaceResearch and Analysis MethodsContinuum Mechanics010309 optics03 medical and health sciencesSine Waves0103 physical sciencesHumansStatistical MethodsFluid FlowVision OcularHueColor Visionbusiness.industrylcsh:RBiology and Life SciencesFluid Dynamics030104 developmental biologyFOS: Biological scienceslcsh:QArtificial intelligencebusinessMathematical FunctionsMathematicsPhotic StimulationSoftwareNeurosciencePLOS ONE
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A statistical study of the additivity of substituent effects on the5J(HH) long-range coupling constant of the formyl proton in substituted benzaldehy…

1982

The additivity of chloro and hydroxy substituent effects on the formyl proton spin-spin coupling constants with the meta ring proton, 5J(HH), has been tested with 15 chlorinated benzaldehydes and hydroxybenzaldehydes by multiple linear regression analysis. No general additivity rule was detected with whole data. Using benzaldehyde as the reference substance, a good correlation was achieved for p-hydroxybenzaldehydes. The same reference compound was not suitable for o-hydroxy derivatives; a much better correlation was observed using o-hydroxybenzaldehyde as a reference compound in the latter case.

Coupling constantRange (particle radiation)ProtonStereochemistrySubstituentGeneral ChemistryRing (chemistry)Benzaldehydechemistry.chemical_compoundchemistryComputational chemistryAdditive functionGeneral Materials ScienceMultiple linear regression analysisOrganic Magnetic Resonance
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Community Perilaku Masyarakat dalam Mengelola Sampah Rumah Tangga di Distrik Manokwari Timur Kabupaten Manokwari

2020

This study aims to (1) determine the behavior of the community in managing household waste in Manokwari Timur District, Manokwari Regency, (2) to analyze the factors that influence people's behavior in managing household waste. This research was conducted in Manokwari Regency, West Papua Province. The research method used is descriptive quantitative with data analysis using multiple regression analysis. The results showed: (1) The overall behavior of the community in managing household waste in East Manokwari District (65.5%) was in the sufficiently supportive category. Meanwhile, as many as 34.9% are in the unsupported category, (2) The results of multiple linear regression analysis show t…

Household wasteGeographyFormal educationRegression analysisMultiple linear regression analysisGeneral MedicineSocioeconomicsAffect (psychology)Descriptive quantitativeTest (assessment)Research methodCassowary
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Relationship among Corneal Biomechanics, Refractive Error, and Axial Length

2014

Purpose To evaluate the relationship between different ocular and corneal biomechanical parameters in emmetropic and ametropic healthy white children. Methods This study included 293 eyes of 293 healthy Spanish children (135 boys and 158 girls), ranging in age from 6 to 17 years. Subjects were divided according to the refractive error: control (emmetropia, 99 children), myopia (100 children), and hyperopia (94 children) groups. In all cases, corneal hysteresis (CH) and corneal resistance factor (CRF) were evaluated with the Ocular Response Analyzer system. Axial length (AL) and mean corneal power were also measured by partial coherence interferometry (IOLMaster), and central corneal thickne…

Malemedicine.medical_specialtyRefractive errorIntraocular pressureocular parametersAdolescentgenetic structuresAnterior ChamberVisual AcuityEmmetropiaCorneachildrenOphthalmologyHumansMedicinerefractive errorChildIntraocular PressureDioptreÓpticabusiness.industryBiomechanicsHigh myopiaAxial lengthElastic TissueRefractive Errorsmedicine.diseaseeye diseasesBiomechanical PhenomenaAxial Length EyeOphthalmologyCross-Sectional Studiesagecorneal biomechanical propertiesRegression AnalysisOptometryFemaleMultiple linear regression analysissense organsbusinessTomography Optical CoherenceOptometryOptometry and Vision Science
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DesMol2, an Effective Tool for the Construction of Molecular Libraries and Its Application to QSAR Using Molecular Topology

2019

A web application, DesMol2, which offers two main functionalities, is presented: the construction of molecular libraries and the calculation of topological indices. These functionalities are explained through a practical example of research of active molecules to the formylpeptide receptor (FPR), a receptor associated with chronic inflammation in systemic amyloidosis and Alzheimer&rsquo

Models MolecularMultilinear mapQuantitative structure–activity relationshiplinear discriminant analysisComputer scienceQuantitative Structure-Activity RelationshipPharmaceutical ScienceComputational biology01 natural sciencesArticleAnalytical ChemistrySmall Molecule Librarieslcsh:QD241-44103 medical and health scienceslcsh:Organic chemistryDrug DiscoveryPhysical and Theoretical ChemistryPiperazineDesMol2030304 developmental biology0303 health sciencesMolecular Structure010405 organic chemistryOrganic Chemistrymolecular librariesBase (topology)Linear discriminant analysisReceptors Formyl PeptideSystemic amyloidosis0104 chemical sciencestopology descriptorsmultilinear regression analysisDiscriminantChemistry (miscellaneous)Molecular MedicineMultiple linear regression analysisMolecular topologyAlzheimer’s diseaseDatabases ChemicalSoftwareProtein BindingMolecules
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Multiple linear regression analysis of RF values of chlorinated catechols and guaiacols

1981

The multiple linear regression analysis of the RF values of chlorinated catechols and guaiacols has been carried out. The resolved terms, in the regression equation have been used to explain the relative mobility of chlorinated compounds to the reference compound (catechol or guaiacol). The best correlations have been observed for solvent systems which give the greatest standard deviations and relative differences between the RF values. A good correlation between the standard deviation of the RF values and the term which represents the effect of the chlorine atom ortho to the hydroxyl group(s) have also been observed.

Solvent systemCatecholOrganic ChemistryClinical BiochemistryChlorine atomAnalytical chemistryRegression analysisBiochemistryStandard deviationAnalytical Chemistrychemistry.chemical_compoundchemistrypolycyclic compoundsMultiple linear regression analysisGuaiacolChromatographia
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