Search results for "Lip"
showing 10 items of 8306 documents
The impact of coffee on health
2013
Abstract Objective Coffee is a beverage used worldwide. It includes a wide array of components that can have potential implication on health. We have reviewed publications on the impact of coffee on a series of health outcomes. Methods Articles published between January 1990 and December 2012 were selected after crossing coffee or caffeine with a list of keywords representative of the most relevant health areas potentially affected by coffee intake. Results Caffeine, chlorogenic acids and diterpenes are important components of coffee. Tolerance often acts as a modulator of the biological actions of coffee. There is a significant impact of coffee on the cardiovascular system, and on the meta…
Linguistic Diversity as a Problem and a Resource – Multilingualism in European and Finnish Policy Documents
2012
Societies in Europe and across the world are under constant pressure to cope with increasing multilingualism and multiculturalism. This development has its roots in different global and local societal and economic processes. On the one hand, globalization is putting pressure on the economy in that more varied language resources are needed in society. On the other hand, immigration is constantly on the increase, giving rise to what Vertovec (2006) has termed super-diversity, a ‘condition distinguished by a dynamic interplay of variables among an increased number of new, small and scattered, multiple-origin, transnationally connected, socio-economically differentiated and legally stratified i…
Relative expression of cholesterol transport-related proteins and inflammation markers through the induction of 7-ketosterol-mediated stress in Caco-…
2013
Human diets contain sterol oxidation products that can induce cytotoxic effects, mainly caused by cholesterol oxides. However, phytosterol oxides effects have been less extensively investigated. This study evaluates the production of inflammatory biomarkers (IL-1β, IL-8, IL-10, TNFα) and the influence of gene expression transporters and enzymes related to cholesterol absorption and metabolism (NPC1L1, ABCG5/8, HMGCoA, ACAT) produced by 7-ketosterols (stigmasterol/cholesterol) in Caco-2 cells. These effects were linked to intracellular signaling pathways by using several inhibitors. Results showed 7-ketostigmasterol to have a greater proinflammatory potential than 7-ketocholesterol. In non-p…
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10
2001
Biochemical, epidemiological, and genetic findings demonstrate a link between cholesterol levels, processing of the amyloid precursor protein (APP), and Alzheimer's disease. In the present report, we identify the α-secretase ADAM 10 ( a d isintegrin a nd m etalloprotease) as a major target of the cholesterol effects on APP metabolism. Treatment of various peripheral and neural cell lines with either the cholesterol-extracting agent methyl-β-cyclodextrin or the hydroxymethyl glutaryl-CoA reductase inhibitor lovastatin resulted in a drastic increase of secreted α-secretase cleaved soluble APP. This strong stimulatory effect was in the range obtained with phorbol esters and was further increa…
Frustrats, incompresos i oblidats: els expedicionaris espanyols de la il·lustració
2013
En l’ultim terc del segle XVIII la corona espanyola es va incorporar a la practica de promoure expedicions que, junt amb la reivindicacio sobre els territoris visitats, elaboraren tambe estudis i catalegs de les riqueses naturals trobades. La majoria dels expedicionaris van topar a la tornada amb la incomprensio i l’oblit de les mateixes institucions que havien promogut el seu viatge.
Gene expression is stronger associated with behaviour than with age and fertility in ant workers
2018
AbstractThe ecological success of social insects is based on division of labour, not only between queens and workers, but also among workers. Whether a worker tends the brood or forages is strongly influenced by age, fertility and nutritional status, with brood carers being younger, more fecund and corpulent. Here, we experimentally disentangle behaviour from age and fertility inTemnothorax longispinosusant workers and analyse how these parameters are linked to whole-body gene expression. Our transcriptome analysis reveals four times more genes associated with behaviour than with age and only few fertility-associated genes. Brood carers exhibited an upregulation of genes involved in lipid b…
Continuity and Discontinuity of Sport and Exercise Type During the COVID-19 Pandemic : An Exploratory Study of Effects on Mood
2020
Involvement in sport and exercise not only provides participants with health benefits but can be an important aspect of living a meaningful life. The COVID-19 pandemic and the temporary cessation of public life in March/April/May 2020 came with restrictions, which probably also made it difficult, if not impossible, to participate in certain types of sport or exercise. Following the philosophical position that different types of sport and exercise offer different ways of “relating to the world,” this study explored (dis)continuity in the type of sport and exercise people practiced during the pandemic-related lockdown, and possible effects on mood. Data from a survey of 601 adult exercisers, …
On the social meanings inherent in literacy campaigns
1990
Artikkelissa tarkastellaan luku- ja kirjoitustaitokampanjoita käsittelevän kansainvälisen dokumenttiaineiston perusteella sitä, millaisia merkityksiä sisältyy lukuja kirjoitustaidottomuuden määrittelyyn yhteiskunnalliseksi ongelmaksi, ja asetetaan kyseenalaiseksi tässä aineistossa ilmenevä yleismaailmallinen ideologia. Lisäksi pohditaan luku- ja kirjoitustaidon mahdollisista emansipatorista merkitystä kehitysmaiden oloissa.
Data from: Ergosterol biosynthesis: a fungal pathway for life on land?
2012
Sterols, essential lipids of most eukaryotic cells, ensure important structural and signaling functions. The selection pressure which has led to different dominant sterols in the three eukaryotic kingdoms remains unknown. Here we investigated the influence of the progression in the different steps of the ergosterol biosynthetic pathway (EBP) on the yeast resistance to transitions from aqueous to aerial media, typical perturbations of the higher fungi habitats. Five mutants of the EBP (ergΔ), accumulating different sterol intermediates in the EBP, and the WT strain were exposed to drying under atmospheric air or nitrogen and wetting. Results show that the progression in the EBP parallels an …