Search results for "Llum"

showing 10 items of 570 documents

Una Praeparatio ad Missam Pontificalem miniata da Jacopo Ravaldi per l’arcivescovo Ausiàs Despuig ritrovata a Monreale. Prime considerazioni

2022

Il saggio presenta alla comunità scientifica un manoscritto miniato quattrocentesco del Tesoro della Cattedrale di Monreale già noto ad Angela Daneu Lattanzi e recentemente ritrovato, attribuendone la committenza al cardinale Ausias Despuig e la paternità al miniatore francese Jacopo Ravaldi attivo a Roma. The essay presents to the scholarly community a 15th-century illuminated manuscript from the Treasury of the Cathedral of Monreale already known to Angela Daneu Lattanzi and recently rediscovered, attributing its commission to Cardinal Ausias Despuig and its authorship to the French illuminator Jacopo Ravaldi active in Rome.

Romamanoscritti e incunaboli miniatiAusiàs DespuigSettore L-ART/01 - Storia Dell'Arte Medievaleilluminated manuscripts and incunabulaRomeJacopo RavaldiAusias DespuigMonreale
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Recenti scoperte a Gela: il sacello suburbano di Piazza Gorizia

2012

In the winter of 2001-2002, an emergency excavation uncovered another suburban sanctuary in the periphery of ancient Gela (Piazza Gorizia). During the excavations remains of a sacellum and a votive depot datable at the end of 5th century BC were found.

Sacellum Gela votive deposit 5th century BCSettore L-ANT/10 - Metodologie Della Ricerca Archeologica
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Next-Generation Sequencing in Clinical Practice

2019

Abstract During the past few decades, Sanger sequencing represented the “gold standard” technique. In order to better define the mutational status of several genes at the same time, next-generation sequencing methodologies have been introduced in the molecular laboratory workflow. In the era of personalized medicine, this technological improvement plays a key role in the comprehensive molecular characterization of cancer patients in order to get a “tile” target therapy. For different cancer patients, different target therapies are available and different genes serve as clinical it relevant biomarkers. This chapter reviews the principal features of these novel technologies and their applicat…

Sanger sequencingCirculating tumor dnaLiquid biopsyIon torrentbusiness.industryComputer scienceCancerDNAGold standard (test)Computational biologymedicine.diseaseGene readerTarget therapyDNA sequencingClinical Practicesymbols.namesakeWorkflowIlluminaNext-generation sequencingmedicinesymbolsRNAMutational statusPersonalized medicinebusiness
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Isolation of the silicatein-α interactor silintaphin-2 by a novel solid-phase pull-down assay.

2011

The skeleton of siliceous sponges consists of amorphous biogenous silica (biosilica). Biosilica formation is driven enzymatically by means of silicatein(s). During this unique process of enzymatic polycondensation, skeletal elements (spicules) that enfold a central proteinaceous structure (axial filament), mainly comprising silicatein, are formed. However, only the concerted action of silicatein and other proteins can explain the genetically controlled diversity of spicular morphotypes, from simple rods with pointed ends to intricate structures with up to six rays. With the scaffold protein silintaphin-1, a first silicatein interactor that facilitates the formation of the axial filament and…

Scaffold proteinSpiculeImmunoprecipitationMolecular Sequence DataNanotechnologyBiologyFlagellumBiochemistry03 medical and health sciencesSponge spiculePhase (matter)Two-Hybrid System TechniquesProtein Interaction MappingAnimalsInteractorAmino Acid Sequence030304 developmental biology0303 health sciences030302 biochemistry & molecular biologySilicon DioxideCathepsinsYeastProtein TransportSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationBiophysicsAutoradiographyCalciumSuberitesProtein BindingBiochemistry
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Technical‐economic evaluation of the effectiveness of measures applied to the artificial lighting system of a school

2021

Ensuring optimum interior lighting is a topic of great importance, as this influences not only the well-being of users but also the optimal performance of visual tasks. Lighting can be natural, but if not sufficient, it can be compensated with artificial lighting. This study highlights a methodology for designing a new lighting system that takes into account both technical and economic aspects. The method was applied to an existing school located in southern Italy, in which the electricity consumption is related to the current lighting system. The school is chosen as being representative of the construction type and layout of many local schools. In addition, the coexistence of several visua…

SchoolArchitectural engineeringTechnologyComputer scienceQH301-705.5020209 energyQC1-999LENI02 engineering and technology010501 environmental sciences01 natural sciencesDimmingIlluminancelaw.inventionlaw0202 electrical engineering electronic engineering information engineeringGeneral Materials ScienceDaylightBiology (General)InstrumentationQD1-999Lighting0105 earth and related environmental sciencesFluid Flow and Transfer ProcessesConsumption (economics)Artificial lightbusiness.industryProcess Chemistry and TechnologyTPhysicsLEDGeneral EngineeringEnergy consumptionEngineering (General). Civil engineering (General)ComfortComputer Science ApplicationsLED lampDynamic simulationEnergy consumptionChemistryEconomic evaluationDaylightElectricityTA1-2040businessDynamic simulation
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Integration of Gravitational Torques in Cerebellar Pathways Allows for the Dynamic Inverse Computation of Vertical Pointing Movements of a Robot Arm

2008

BackgroundSeveral authors suggested that gravitational forces are centrally represented in the brain for planning, control and sensorimotor predictions of movements. Furthermore, some studies proposed that the cerebellum computes the inverse dynamics (internal inverse model) whereas others suggested that it computes sensorimotor predictions (internal forward model).Methodology/principal findingsThis study proposes a model of cerebellar pathways deduced from both biological and physical constraints. The model learns the dynamic inverse computation of the effect of gravitational torques from its sensorimotor predictions without calculating an explicit inverse computation. By using supervised …

ScienceComputationComputational Biology/Computational NeuroscienceModels BiologicalInverse dynamicsComputer Science::Robotics03 medical and health sciences0302 clinical medicineNeuroscience/Motor SystemsGravitational fieldControl theoryCerebellum030304 developmental biologyPhysics0303 health sciencesNeuroscience/Behavioral NeuroscienceMultidisciplinaryQuantitative Biology::Neurons and CognitionArtificial neural networkbusiness.industryQRRoboticsRoboticsCerebellar cortexMedicineRobotArtificial intelligencebusinessRobotic arm030217 neurology & neurosurgeryGravitationResearch ArticlePLoS ONE
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When the brain goes diving: glial oxidative metabolism may confer hypoxia tolerance to the seal brain.

2009

Deep diving mammals have developed strategies to cope with limited oxygen availability when submerged. These adaptations are associated with an increased neuronal hypoxia tolerance. Brain neurons of the hooded seal Cysto- phora cristata remain much longer active in hypoxic condi- tions than those of mice. To understand the cellular basis of neuronal hypoxia tolerance, we studied neuroglobin and cy- tochrome c in C. cristata brain. Neuroglobin, a respiratory protein typically found in vertebrate neurons, displays three unique amino acid substitutions in hooded seal. However, these substitutions unlikely contribute to a modulation of O2 affinity. Moreover, there is no significant difference i…

Seals EarlessCentral nervous systemMolecular Sequence DataNeuroglobinNerve Tissue ProteinsBiologyRats Sprague-DawleyMiceSpecies SpecificityCerebellummedicinePremovement neuronal activityAnimalsAmino Acid SequenceHypoxia Brainchemistry.chemical_classificationNeuronsReactive oxygen speciesMice Inbred BALB CSequence Homology Amino AcidGeneral NeuroscienceBrainCytochromes cHypoxia (medical)Cell biologyGlobinsRatsRespiratory proteinMice Inbred C57BLmedicine.anatomical_structureBiochemistrychemistryAmino Acid SubstitutionNeuroglobinAstrocytesNeurogliaFemalemedicine.symptomNeurogliaAstrocyteNeuroscience
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Quantitative Multispectral Imaging Differentiates Melanoma from Seborrheic Keratosis.

2021

Melanoma is a melanocytic tumor that is responsible for the most skin cancer-related deaths. By contrast, seborrheic keratosis (SK) is a very common benign lesion with a clinical picture that may resemble melanoma. We used a multispectral imaging device to distinguish these two entities, with the use of autofluorescence imaging with 405 nm and diffuse reflectance imaging with 525 and 660 narrow-band LED illumination. We analyzed intensity descriptors of the acquired images. These included ratios of intensity values of different channels, standard deviation and minimum/maximum values of intensity of the lesions. The pattern of the lesions was also assessed with the use of particle analysis. …

Seborrheic keratosisMedicine (General)diagnosisClinical BiochemistryMultispectral image01 natural sciencesArticleautofluorescence imaging010309 optics030207 dermatology & venereal diseases03 medical and health sciencesR5-9200302 clinical medicinediffuse reflectance imaging0103 physical sciencesmelanomaMedicineLed illuminationquantitative analysisbusiness.industryMelanomaLEDBenign lesionmedicine.diseaseIntensity (physics)Autofluorescencemelanoma; seborrheic keratosis; autofluorescence imaging; LED; dermoscopy; quantitative analysis; diffuse reflectance imaging; diagnosisseborrheic keratosisImaging techniquedermoscopybusinessNuclear medicineDiagnostics (Basel, Switzerland)
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Knowledge engineering and semantic formalism of symbolic relations. From medieval network to web 3.0

2020

A search has always been at the center of human concerns, the one of conditions and means to represent, to control well, and to communicate effectively with his environment. While technological advances and electronic gadgets such as smartphones, the Web, and online social networks currently allow addressing this concern, it has not always been the case. Our works in this thesis treat medieval documents considered as a medium of communication and as a model of the social network in the Middle Ages. These documents are called medieval illuminations. They were luxurious paintings used in that time to represent the environment and ideal world for elites such as prince, duke, etc. Those paintin…

Semantic Relation / Influencial RelationRéseau SociauxRelation Sémantique / Relation d'influence[INFO.INFO-TI] Computer Science [cs]/Image Processing [eess.IV]OntologyIngénierie des ConnaissancesEnluminure MédiévaleNumérisation du Patrimoine CulturelKnowledge EngineeringSocial NetworkCultural heritage DigitalisationOntologieMedieval Illumination
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Age-related changes in the regulation of transcription factor NF-kappa B in rat brain.

1997

Aging process involves an increase in stress at cellular level. We studied whether aging affects the regulation of stress responsive transcription factor NF-kappa B in brain samples of Wistar rats. Hippocampus, cerebellum, and temporal and frontal lobes of cortex were studied. We observed a significant up-regulation in the constitutive, nucleus-located NF-kappa B binding activity in 30-month-old Wistar rats compared to young and 18-month-old rats. The increase was most prominent in cerebellum and in frontal cortex, but age-related changes did not occur in hippocampus. Inducible, cytoplasmic NF-kappa B binding activity was not affected by aging in any of the samples studied. Western blot ass…

SenescenceMalemedicine.medical_specialtyAgingP50HippocampusNerve Tissue ProteinsBiologyHippocampuschemistry.chemical_compoundWestern blotInternal medicineCerebellummedicineAnimalsRats WistarTranscription factorRegulation of gene expressionCell Nucleusmedicine.diagnostic_testGeneral NeuroscienceNF-kappa BBrainNF-κBTemporal LobeCell biologyFrontal LobeRatsUp-RegulationB vitaminsEndocrinologychemistryGene Expression RegulationFemaleProtein BindingNeuroscience letters
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