Search results for "Local"

showing 10 items of 4112 documents

Unilateral Accessory Sacroiliac Joint with Bone Marrow Edema Mimicking Sacroiliitis.

2018

Accessory sacroiliac joint (SIJ) is described as a common anatomical variant, identified in 13–18% and up to 40% of the general population1,2. It can be unilateral or bilateral and is related to aging, obesity, or women with multiple deliveries2,3. The patient, a 53-year-old white woman, presented with low back pain and left buttock pain for 6 months. She had no fever and local pressure on left SIJ reproduced …

medicine.medical_specialtyImmunologyDiagnosis Differential03 medical and health sciences0302 clinical medicineRheumatologyBone MarrowmedicineImmunology and AllergyLocal pressureEdemaHumansSacroiliitisBone Marrow Diseases030203 arthritis & rheumatologySacroiliac jointbusiness.industrySacroiliitisSacroiliac JointMiddle Agedmedicine.diseaseBone marrow edemaLow back painMagnetic Resonance Imagingmedicine.anatomical_structureLeft buttockFemaleRadiologymedicine.symptombusiness030217 neurology & neurosurgeryThe Journal of rheumatology
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Perioperative chemotherapy versus surgery alone for resectable colorectal liver metastases: an international multicentre propensity score matched ana…

2021

Abstract Background There is still uncertainty regarding the role of perioperative chemotherapy (CTx) in patients with resectable colorectal liver metastases (CRLM), especially in those with a low-risk of recurrence. Methods Multicentre retrospective analysis of patients with CRLM undergoing liver resection between 2010–2015. Patients were divided into two groups according to whether they received perioperative CTx or not and were compared using propensity score matching (PSM) analysis. Then, they were stratified according to prognostic risk scores, including: Clinical Risk Score (CRS), Tumour Burden Score (TBS) and Genetic And Morphological Evaluation (GAME) score. Results The study includ…

medicine.medical_specialtyIndependent predictorResection03 medical and health sciences0302 clinical medicineRisk FactorsPerioperative chemotherapyLong term outcomesmedicineOverall survivalHepatectomyHumansPropensity ScoreRetrospective StudiesHepatologybusiness.industryLiver NeoplasmsGastroenterologyPerioperativePrognosisSurgery030220 oncology & carcinogenesisPropensity score matching030211 gastroenterology & hepatologyNeoplasm Recurrence LocalColorectal NeoplasmsbusinessClinical risk factorHPB
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Cartridge syringe vs computer controlled local anesthetic delivery system: Pain related behaviour over two sequential visits - a randomized controlle…

2015

Background: Local anesthetic injection is one of the most anxiety provoking procedure in dentistry. Knowledge about change in pain related behaviour during consecutive visits helps in and scheduling of treatment procedures and management of children in dental clinic. Aim: To compare the pain perception, behavioural response and the associated change in physiological parameters while receiving local anesthesia injection with cartridge syringe and computer controlled local anesthetic delivery system (CCLAD) over two consecutive visits. Material and Methods: In this randomized controlled cross over trial, 120 children aged 7 – 11 years were randomly divided into group A: receiving injections w…

medicine.medical_specialtyInjection Procedurebusiness.industryLocal anestheticmedicine.drug_classResearchOdontología:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludCrossover studyOrofacial pain-TMJDSurgerylaw.inventionRandomized controlled triallawAnesthesiaUNESCO::CIENCIAS MÉDICASFLACC scalemedicineAnxietyLocal anesthesiamedicine.symptombusinessGeneral DentistrySyringeJournal of Clinical and Experimental Dentistry
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Intra-operative locally injected pharmacotherapy as a novel strategy for adhesion prophylaxis.

2012

Abstract Background Pharmacotherapy for peritoneal adhesion prophylaxis has been a focus for intensive research. Previous strategies included intravenous and intraperitoneal application of suitable pharmaceutical agents. However, success of these strategies in humans has been limited. Here we describe intra-operative local injection of pharmaceuticals as a novel strategy for adhesion prophylaxis. Methods N  = 208 peritoneal lesions were created in 26 adult Wistar rats. In each animal, lesions on one flank were randomly chosen for treatment with locally injected prednisolone whereas the contralateral side was injected with normal saline. Half of the animals were randomly selected for early a…

medicine.medical_specialtyIntra operativeAdhesionsmedicine.medical_treatmentPrednisoloneAnti-Inflammatory AgentsAdhesion (medicine)Tissue AdhesionsPeritoneal DiseasesStatistics NonparametricRandom AllocationPharmacotherapyLocal injectionStatistical significanceAbdomenmedicineAnimalsLocal anesthesiaRats WistarSteroidSalineIntraoperative Carebusiness.industryHistocytochemistryGeneral Medicinemedicine.diseaseSurgeryRatsDisease Models AnimalPrednisoloneSurgeryPeritoneumbusinessLocal injectionInjections Intraperitonealmedicine.drugInternational journal of surgery (London, England)
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Hemodynamic changes following injection of local anesthetics with different concentrations of epinephrine during simple tooth extraction: A prospecti…

2015

Background Presence of epinephrine in local anesthetic cartridge increases the duration of local anesthesia (LA), decreases the risk of toxicity, and provides hemostasis. However, the unfavorable effects are increasing heart rate (HR) and raising blood pressure (BP). The aim was to evaluate hemodynamic changes in the BP, HR, and oxygen saturation (SpO2) of normal patients undergoing tooth extraction using LA with various epinephrine concentrations. Material and Methods A prospective randomized clinical trial was conducted on 120 patients who were divided randomly into 3 parallel groups according to the LA received. Group 1: lidocaine 2% with epinephrine 1:80,000 (L80). Group 2: articaine 4%…

medicine.medical_specialtyLidocaineLocal anestheticmedicine.drug_classbusiness.industryResearchHemodynamicsOdontologíaArticaine:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludSurgeryBlood pressureEpinephrineAnesthesiaHeart rateUNESCO::CIENCIAS MÉDICASmedicineLocal anesthesiaOral SurgerybusinessGeneral Dentistrymedicine.drugJournal of Clinical and Experimental Dentistry
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Surgical sphincter saving approach and topical nifedipine for chronic anal fissure with hypertonic internal anal sphincter

2020

PURPOSE The role of augmented internal anal sphincter (IAS) tone in the genesis of posterior chronic anal fissure (CAPF) is still unknown. Lateral internal sphincterotomy is the most employed surgical procedure, nevertheless it is burdened by high risk post-operative anal incontinence. The aim of our study is to evaluate results of sphincter saving procedure with post-operative pharmacological sphincterotomy for patients affected by CAPF with IAS hypertonia. Methods: We enrolled 30 patients, undergone fissurectomy and anoplasty with V-Y cutaneous flap advancement; all patients received topical administration of nifedipine 0.3% and lidocaine 1.5% ointment-based therapy before and for 15 days…

medicine.medical_specialtyLidocaineNifedipinemedicine.medical_treatmentAdministration TopicalAnal CanalSurgical FlapsInternal anal sphincterFissurectomyOintmentsMuscle HypertoniaNifedipineMuscle HypertoniamedicineHumansProspective StudiesAnesthetics LocalAnestheticsAnal fissureAnal fissure Anoplasty Fissurectomy Lidocaine Nifedipine Proctology Administration Topical Anal Canal Anesthetics Local Calcium Channel Blockers Chronic Disease Combined Modality Therapy Humans Lidocaine Muscle Hypertonia Ointments Prospective Studies Surgical Flaps Treatment Outcome Fissure in Ano Nifedipinebusiness.industryLidocaineAnal canalAnoplastymedicine.diseaseCalcium Channel BlockersCombined Modality TherapySurgerymedicine.anatomical_structureTreatment OutcomeTopicalLocalAdministrationChronic DiseaseHypertoniaSurgeryFissure in Anomedicine.symptomAnal fissureProctologyLateral internal sphincterotomybusinessmedicine.drug
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Comparison of anesthetic efficacy of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine for inferior alveolar nerve b…

2014

Objectives: This study was done to compare the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine with that of 2% lidocaine with 1:80,000 epinephrine during pulpectomy in patients with irreversible pulpitis for inferior alveolar nerve block in mandibular posterior teeth. Material and Methods: Patients with irreversible pulpitis referred to the Department of Conservative Dentistry and Endodontics, K.D. Dental College, randomly received a conventional inferior alveolar nerve block containing 1.8 mL of either 4% articaine with 1:100,000 epinephrine or 2% lidocaine with 1:80,000 epinephrine. After the patient's subjective assessment of lip anesthesia, the absence/presence of pulpal …

medicine.medical_specialtyLidocainebusiness.industryLocal anestheticmedicine.drug_classResearchDentistryOdontologíaInferior alveolar nervemedicine.diseaseEndodonticsArticaine:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludOperative Dentistry and EndodonticsEpinephrinestomatognathic systemAnesthesiaAnestheticUNESCO::CIENCIAS MÉDICASmedicinePulpitisbusinessGeneral Dentistrymedicine.drug
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Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow

2017

A patient's willingness to cooperate is an absolute precondition for successful awake intubation of the trachea. Whilst drug-sedation of patients can jeopardize their spontaneous breathing, topical anesthesia of the airway is a popular technique. The spray-as-you-go technique represents one of the simplest opportunities to anesthetize the airway mucosa. The application of local anesthetic through the working channel of the flexible endoscope is a widespread practice for anesthetists as well as pulmonologists. There is neither need for additional devices nor special training as a pre-requisite to perform this technique. However, a known clinical problem is the coughing and gagging reflex tha…

medicine.medical_specialtyLidocainemedicine.drug_classmedicine.medical_treatmentGeneral Chemical Engineering030204 cardiovascular system & hematologyGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicinePharyngeal reflexAnesthesiologymedicineIntubation IntratrachealIntubationHumansAnesthetics LocalGeneral Immunology and MicrobiologyLocal anestheticbusiness.industryGeneral NeuroscienceLidocaineEndoscopySurgeryOxygen030220 oncology & carcinogenesisAnesthesiaAnestheticBreathingMedicinebusinessAirwaymedicine.drugAnesthesia Local
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Endorektale Sonographie zur präoperativen Beurteilung der Infiltrationstiefe von Rektumtumoren

1990

From June 1987 to February 1990, 142 out of 319 patients with rectal tumours were investigated by ultrasound scanning with the object of ascertaining the depth to which the tumour had infiltrated. This examination proved completely feasible in 130 of these patients (84 men, 46 women, mean age 61.7 [42-84] years). Postoperative histological examination revealed an adenoma (n = 59) or a T1 carcinoma (n = 19), while intrarectal ultrasonography disclosed the same findings in 79 patients (true-positive in 75 cases). A T2-tumour was diagnosed by histological examination in 24 patients, and by ultrasonography in 22 (true-positive in 18 cases). The histological diagnosis of a tumour in stage T3 or …

medicine.medical_specialtyLocal excisionAdenomabusiness.industryUltrasoundGeneral MedicineRectal Tumorsmedicine.diseaseCarcinomaMedicineRadiologyStage (cooking)UltrasonographybusinessInfiltration (medical)DMW - Deutsche Medizinische Wochenschrift
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Die transanale endoskopische mikrochirurgische Behandlung von „low risk“ und „high risk“ Karzinomen der Rektumschleimhaut

1993

Transanal endoscopic microsurgery was performed in 78 patients with rectal carcinoma. Complications were observed in two patients (2.5%), no patient died after local excision. In case of local excised “low risk” T1-carcinoma and tumor free margins no recurrences were observed.

medicine.medical_specialtyLocal excisionbusiness.industrymedicine.medical_treatmentRectal carcinomamedicineMicrosurgerybusinessTumor-Free MarginsSurgery
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