Search results for "Localization function"

showing 10 items of 56 documents

1,3-Dipolar cycloadditions of electrophilically activated benzonitrile N-oxides. Polar cycloaddition versus oxime formation.

2006

The reactions of electrophilically activated benzonitrile N-oxides (BNOs) toward 3-methylenephthalimidines (MPIs) have been studied using density functional theory (DFT) at the B3LYP/6-31G* level. For these reactions, two different channels allowing the formation of the [3 + 2] cycloadducts and two isomeric (E)- and (Z)-oximes have been characterized. The 1,3-dipolar cycloadditions take place along concerted but highly asynchronous transition states, while formation of the oximes is achieved through a stepwise mechanism involving zwitterionic intermediates. Both reactions are initiated by the nucleophilic attack of the methylene carbon of the MPIs to the carbon atom of the electrophilically…

Benzonitrilechemistry.chemical_compoundchemistryNucleophileStereochemistryOrganic ChemistrySolvent effectsMethylenePhotochemistryTransition stateCycloadditionElectron localization functionNatural bond orbitalThe Journal of organic chemistry
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Electronic fluxes during diels-alder reactions involving 1,2-benzoquinones: mechanistic insights from the analysis of electron localization function …

2012

By means of the joint use of electron localization function (ELF) and Thom's catastrophe theory, a theoretical analysis of the energy profile for the hetero-Diels-Alder reaction of 4-methoxy-1,2-benzoquinone 1 and methoxyethylene 2 has been carried out. The 12 different structural stability domains obtained by the bonding evolution theory have been identified as well as the bifurcation catastrophes (fold and cusp) responsible for the changes in the topology of the system. This analysis permits finding a relationship between the ELF topology and the evolution of the bond breaking/forming processes and electron pair rearrangements through the reaction progress in terms of the different ways o…

Diels-Alder reactionsElectron pairElectron localization functionMolecular StructureChemistryCatastrophe theoryRegioselectivityElectronsGeneral ChemistryElectron localization function12-benzoquinonesComputational MathematicsRegioselectivityEnergy profileNucleophileChemical physicsComputational chemistryElectrophileBenzoquinonesQuantum TheoryDensity functional theoryCatastrophe theoryJournal of Computational Chemistry
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Closer Investigation of the Kinetics and Mechanism of Spirovinylcyclopropyl Oxindole Reaction with 3Σ–g-O2 by Topological Approaches and Unraveling t…

2021

In this investigation at the MN15L/Def2-TZVP level of theory, we present computational evidence indicating that the reaction of 3Σ-g-O2 with spirovinylcyclopropyl oxindole (2) leads to a product called spiro-1,2-dioxolane (2) in its singlet state; this reaction occurs via a stepwise mechanism and its rate-determining step is catalyzed by iodine radicals, which promotes opening of the three-membered ring under dark conditions. The conversion of 2 to 1-benzylindoline-2,3-dione (3) and 2-vinyloxirane (4) takes place via a concerted and slightly asynchronous reaction. Both electron localization function and AIM topological analysis reveal that the step associated with the attack of the 3Σ-g-O2 …

chemistry.chemical_compoundchemistryRadicalSingle bondMoleculeOxindoleSinglet statePhysical and Theoretical ChemistryRing (chemistry)TopologyElectron localization functionCatalysisThe Journal of Physical Chemistry A
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Interaction of Au16 Nanocluster with Defects in Supporting Graphite: A Density-Functional Study

2011

Soft-landed adsorption of Au-16 on bilayered graphene is investigated using density functional theory. The orientation of the Au-16 cluster and number of neighboring surface vacancies affect the overall structural and electronic properties of the cluster. The results of the PBE, vdW-DF, and vdW-DF2 exchange-correlation functionals are compared for the cluster-substrate interaction for systems with and without defects. In the presence of defects size two and greater, an Au atom adsorbs into the topmost graphene layer; this strongly influences the binding energy (>3 eV), while inducing substantial bending in the carbon plane and altering electronic properties of the system. Though the T-d-sym…

Binding energyNanotechnology02 engineering and technology010402 general chemistry01 natural scienceslaw.inventionDelocalized electronlawAtomCluster (physics)GraphitePhysical and Theoretical Chemistryta114ChemistryGraphene021001 nanoscience & nanotechnologyElectron localization function0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsJGeneral EnergyChemical physicsddc:540Density functional theory0210 nano-technologyJournal of Physical Chemistry C
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Lithium Cation-Catalyzed Benzene Diels-Alder Reaction: Insights on the Molecular Mechanism Within the Molecular Electron Density Theory.

2020

The lithium cation Li+-catalyzed Diels-Alder (DA) reactions of benzene toward a series of acetylenes of improved nucleophilicity can be described within the context of the molecular electron density theory (MEDT) at the ωB97XD/6-311G(d,p) level. Conceptual density functional theory indices characterize the crown ether solvated complex benzene-lithium Bz-Li-Cro as a superelectrophile. Coordination of a lithium cation to benzene does not change substantially the electron localization function electronic structure of benzene. The DA reaction of Bz-Li-Cro with acetylene shows a reduction of the energy of activation of 6.9 kcal·mol-1, which is not sufficient for the reaction to take place, thus …

chemistry.chemical_classification010405 organic chemistryChemistryOrganic Chemistry010402 general chemistryAlkali metal01 natural sciencesElectron localization function0104 chemical sciencesNucleophileComputational chemistryReactivity (chemistry)Density functional theoryLithium CationCrown etherDiels–Alder reactionThe Journal of organic chemistry
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Unveiling the Unexpected Reactivity of Electrophilic Diazoalkanes in [3+2] Cycloaddition Reactions within Molecular Electron Density Theory

2021

The [3+2] cycloaddition (32CA) reactions of strongly nucleophilic norbornadiene (NBD), with simplest diazoalkane (DAA) and three DAAs of increased electrophilicity, have been studied within the Molecular Electron Density Theory (MEDT) at the MPWB1K/6-311G (d,p) computational level. These pmr-type 32CA reactions follow an asynchronous one-step mechanism with activation enthalpies ranging from 17.7 to 27.9 kcal&middot

analytical_chemistryExergonic reactiondiazoalkanes010405 organic chemistryNorbornadienemolecular electron density theoryGeneral Medicine010402 general chemistry01 natural sciencesCycloadditionElectron localization function3. Good health0104 chemical scienceslcsh:Chemistrychemistry.chemical_compoundlcsh:QD1-999conceptual DFTchemistryNucleophileComputational chemistryelectron localization functionElectrophilenorbornadieneReactivity (chemistry)Acetonitrile
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[1,2,3]Triazolo[1,5-a]pyridines. A theoretical (DFT) study of the ring-chain isomerization

2008

The ring opening isomerization of [1,2,3]triazolo[1,5-a]pyridines to the corresponding 2-pyridyl derivatives has been studied by means of DFT calculations at the B3LYP/6-31+G(d,p) computational level. The effect of the substitution as well as those of protonation, deprotonation, and lithiation on different positions has been studied. The electronic characteristics of the optimized structures have been analyzed by means of the Atoms In Molecules (AIM), Electron Localization Function (ELF), Molecular Electrostatic Potential (MEP), and Natural Bond Orbital (NBO) methodologies. © 2008 Elsevier Ltd. All rights reserved.

DeprotonationComputational chemistryChemistryOrganic ChemistryDrug DiscoveryAtoms in moleculesTriazolopyridineProtonationRing (chemistry)BiochemistryIsomerizationElectron localization functionNatural bond orbital
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Nucleon localization function in rotating nuclei

2020

Background: An electron localization function was originally introduced to visualize bond structures in molecules. It became a useful tool to describe electron configurations in atoms, molecules and solids. In nuclear physics, a nucleon localization function (NLF) has been used to characterize clusters in light nuclei, fragment formation in fission and pasta phases in the inner crust of neutron stars. Purpose: We use the NLF to study the nuclear response to fast rotation. Methods: We generalize the NLF to the case of nuclear rotation. The extended expressions involve both time-even and time-odd local densities. Since current density and density gradient contribute to the NLF primarily at th…

CURRENTSAngular momentumNuclear TheoryMEAN-FIELDNuclear TheoryFOS: Physical sciences114 Physical sciences01 natural sciencesNuclear Theory (nucl-th)Total angular momentum quantum number0103 physical sciencesSUPERDEFORMED BANDSDISTRIBUTIONScollective levelsNeutron010306 general physicsSpin (physics)EQUATIONSPhysicsCRANKED HARMONIC-OSCILLATOR010308 nuclear & particles physicsYrastnucleon distributionnuclear structure and decaysSTATEElectron localization functionComputational physicsELECTRON LOCALIZATIONMean field theorySYMMETRIESydinfysiikkaNucleonPhysical Review C
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Understanding the Participation of Fluorinated Azomethine Ylides in Carbenoid-Type [3 + 2] Cycloaddition Reactions with Ynal Systems: A Molecular Ele…

2021

The carbenoid-type (cb-type) 32CA reaction of 1,1-difluoroated azomethine ylide (DFAY) with phenylpropynal has been studied using the molecular electron density theory (MEDT). Electron localization function (ELF) characterizes DFAY as a carbenoid species participating in cb-type 32CA reactions. The supernucleophilic character of DFAY and the strong electrophilic character of the ynal cause this polar 32CA reaction to have an unappreciable barrier; the reaction, which is highly exothermic, presents total chemo- and regioselectivity. ELF topological analysis of the bonding changes along the reaction establishes its non-concerted two-stage one-step mechanism, in which the nucleophilic attack o…

010405 organic chemistryChemistryOrganic ChemistryAzomethine ylideRegioselectivity010402 general chemistry01 natural sciencesMedicinal chemistryCycloadditionElectron localization function0104 chemical sciencesNucleophileElectrophileReactivity (chemistry)CarbenoidThe Journal of Organic Chemistry
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Unravelling the Mysteries of the [3+2] Cycloaddition Reactions

2018

Bond theory010405 organic chemistryComputational chemistryChemistryOrganic ChemistryPhysical and Theoretical Chemistry010402 general chemistry01 natural sciencesCycloadditionElectron localization function0104 chemical sciencesEuropean Journal of Organic Chemistry
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