Search results for "Loin"

A Statistical Model of Spine Shape and Material for Population-Oriented Biomechanical Simulation

2021

In population-oriented ergonomics product design and musculoskeletal kinetics analysis, digital spine models of different shape, pose and material property are in great demand. The purpose of this study was to construct a parameterized finite element spine model with adjustable spine shape and material property. We used statistical shape model approach to learn inter-subject shape variations from 65 CT images of training subjects. Second order polynomial regression was used to model the age-dependent changes in vertebral material property derived from spatially aligned CT images. Finally, a parametric spine generator was developed to create finite element instances of different shapes and m…

Interest-based topology management in unstructured peer-to-peer networks

2012

Efecto de los factores de crecimiento derivados de las plaquetas en la reparación de defecto óseo cortical

2015

El Plasma Rico en Plaquetas Puro (P-PRP), es un concentrado plaquetario fácilmente disponible para liberar factores de crecimiento a partir de las plaquetas y mejorar la cicatrización del tejido musculo-esquelético. Esta tecnología, no está exenta de controversia, ya que numerosos autores obtienen beneficio en el tratamiento de trastornos de tejidos blandos, en cambio este efecto beneficioso en la consolidación ósea, reparación de fracturas recalcitrantes o regeneración tisular no está tan claro. La gran variabilidad de métodos de preparación y condiciones distintas de uso, proporcionan un alto riesgo de realizar un uso incorrecto o no apropiado.. El objetivo de este trabajo es el estudio d…

Haploinsufficiency of 16.4 Mb from chromosome 22pter-q11.21 in a girl with unilateral conductive hearing loss.

2009

We present the postnatal diagnosis of a de novo der(18)t(18;22)(p11.32;q11.21)pat, resulting in an unbalanced 45,XX,der (18)t(18;22) karyotype in a girl with conductive hearing loss on the left and ptosis of the right upper eye-lid. Unilateral ptosis was also observed in the patient’s 2 years and 8 months younger sister, who grows noticeably faster and appears to be a much quicker learner. After speech therapy the patient was eventually placed in normal school. The haploinsufficient 16.4-Mb region on chromosome 22pter→q11.21 contains 10 genes as well as many predicted genes, pseudogenes, and retrotransposed sequences with unknown functions. This observation may prove useful for prenatal dia…

Limits of lateral expansion in two-dimensional materials with line defects

2021

The flexibility of two-dimensional (2D) materials enables static and dynamic ripples that are known to cause lateral contraction, shrinking of the material boundary. However, the limits of 2D materials' \emph{lateral expansion} are unknown. Therefore, here we discuss the limits of intrinsic lateral expansion of 2D materials that are modified by compressive line defects. Using thin sheet elasticity theory and sequential multiscale modeling, we find that the lateral expansion is inevitably limited by the onset of rippling. The maximum lateral expansion $\chi_{max}\approx 2.1\cdot t^2\sigma_d$, governed by the elastic thickness $t$ and the defect density $\sigma_d$, remains typically well belo…

Numerical simulation of free dissipative open quantum system and establishment of a formula for π

2020

We transform the system/reservoir coupling model into a one-dimensional semi-infinite discrete chain with nearest neighbor interaction through a unitary transformation, and, simulate the dynamics of free dissipative open quantum system. We investigate the consequences of such modeling, which is observed as finite size effect causing the recurrence of particle from the end of the chain. Afterwards, we determine a formula for π in terms of the matrix operational form, which indicates a robustness of the connection between quantum physics and basic mathematics. peerReviewed

Fluid flow simulations meet high-speed video : Computer vision comparison of droplet dynamics

2018

Hypothesis While multiphase flows, particularly droplet dynamics, are ordinary in nature as well as in industrial processes, their mathematical and computational modelling continue to pose challenging research tasks - patent approaches for tackling them are yet to be found. The lack of analytical flow field solutions for non-trivial droplet dynamics hinders validation of computer simulations and, hence, their application in research problems. High-speed videos and computer vision algorithms can provide a viable approach to validate simulations directly against experiments. Experiments Droplets of water (or glycerol-water mixtures) impacting on both hydrophobic and superhydrophobic surfaces …

Simulation environment for the C14-experiment

2016

In this thesis, a simulation environment utilizing Geant4 simulation toolkit was constructed to study the C14 experiment located at the Pyhäsalmi Mine, Finland. The C14 experiment aims to find a liquid scintillator sample with the least amount of 14C, the radioactive isotope of carbon, with concentration preferably less than 10^-18. The scintillator detector used in the experiment consists of a 1.6 liter cylindrical vessel filled with liquid scintillator, two 20 cm conical light guides connected to the ends of the vessel and two low-background photomultiplier tubes to detect scintillator light. In addition, the detector is covered with a reflecting foil. The simulation environment was used …

HSP70, the Key to Account for Erythroid Tropism of Diamond-Blackfan Anemia?

2015

Abstract Diamond-Blackfan anemia (DBA) was the first ribosomopathy identified and is characterized by a moderate to severe, usually macrocytic aregenerative anemia associated with congenital malformations in 50% of the DBA cases. This congenital rare erythroblastopenia is due to a blockade in erythroid differentiation between the BFU-e and CFU-e stages. The link between a haploinsufficiency in a ribosomal protein (RP) gene that now encompass 15 different RP genes and the erythroid defect is still to be fully defined. Recently, mutations in TSR2 and GATA1 genes have been identified in a few DBA families. The GATA1 gene encodes for the major transcription factor critical for erythropoiesis an…

GH successful treatment in a female with a de novo 46,XX,add(X)(p36),t(X;Y)(p36.3;p11.2), growth impairment and SHOX-haploinsufficiency

2019

Abstract Children with chromosome translocations, concerning X chromosome, have a genetic pattern different from Turner syndrome; however, when a translocation involves the of part of X chromosome including short stature homeobox-containing Sex-determining Region Y gene, growth may be severely compromised. We describe the clinical case of a 2.2-year-old-female, arrived at our paediatric unit for a decrease of height velocity. The karyotype was 46,XX,add(X)(p36.3). Array comparative genomic hybridization showed a fragment of Y chromosome, extended from 8.803.981 (Yp11.2) to 28.767.604 (Yq11.23). The final karyotype was 46,XX,add(X)(p36),t(X;Y)(p36.3;p11.2). Fluorescence in situ Hybridization…