Search results for "Longs"

showing 7 items of 17 documents

DECORIN EFFECTS ON PROTEOMIC PROFILING OF BREAST CANCER CELLS: AN UPDATED STUDY

2015

The malignant carcinomas are characterized by several capabilities acquired by the neoplastic cells, among which the ability to invade the extracellular matrix (ECM) and to establish a crosstalk with several ECM components. Under this respect, the extracellular microenvironment is an entity extraordinarily rich of information with opposite signals. Our group has long undertaken the study of the effects of ECM molecules on the behavior of cancer cells in vitro. Among the studied molecules, the decorin was found to exert a non-permissive effect on the growth and motility of the transfected tumor cells. The decorin, belongs to the family of small leucine-rich proteoglycans (SLRP) and is involv…

The malignant carcinomas are characterized by several capabilities acquired by the neoplastic cells among which the ability to invade the extracellular matrix (ECM) and to establish a crosstalk with several ECM components. Under this respect the extracellular microenvironment is an entity extraordinarily rich of information with opposite signals. Our group has long undertaken the study of the effects of ECM molecules on the behavior of cancer cells in vitro. Among the studied molecules the decorin was found to exert a non-permissive effect on the growth and motility of the transfected tumor cells. The decorin belongs to the family of small leucine-rich proteoglycans (SLRP) and is involved physiologically in the fibrillogenesis of collagen. In the last few year a new anti-oncogenic role has been proposed for decorin1. This study aimed to implement the knowledge on the effects of ectopic decorin on breast cancer cells using as a reference point the results already achieved by our research group2 on the experimental model format. By breast cancer cell line 8701-BC and its transfected clone DEC-C2. The extension of the proteomic analysis combined with the mass spectrometry allowed to triplicate the number of identified proteins in our model. Among the newly identified proteins were members of the classes of metabolic enzymes S100 family and cell motility proteins which revealed a net decrease in the decorin transfected cells. Of considerable importance is the observation that these classes of proteins are the most involved in metastatic progression. These results confirm and reinforce the anti-oncogenic role hypothesized for decorin. The work was co-funded by the Italian 5x1000 to COBS.DECORIN
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Beaches in Valencian Coast

2018

The main factors that determined the Valencian beaches characteristics are the configuration of relief structures; fluvial sediment supply; low tidal range; the predominance of low energy waves; scarcity of big storms; longshore littoral drift; and human action. There is a significant prevalence of sandy beaches. Nevertheless, both at the northern part of the Gulf of Valencia and in the structural segment, between the Cape Sant Antoni and Alicante city, pebble and gravel beaches are predominant. Most of the Valencian beaches have experienced significant morphological changes during the last decades due to the human interventions -voluntary or involuntary- in the coastal system. The implemen…

Tidal range010504 meteorology & atmospheric sciencesStorm010502 geochemistry & geophysics01 natural sciencesValencianlanguage.human_languageCoastal erosionLongshore driftOceanographyGeographylanguageSedimentary rockPebbleFluvial sediment0105 earth and related environmental sciences
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Dynamics of sediments along with their core properties in the Monastir-Bekalta coastline (Tunisia, Central Mediterranean)

2017

International audience; The authors report on two campaigns of high-resolution samplings along the shores of Monastir Bay in Tunisia: the first being a study of sediment dynamics, grain size and mineral composition in surface sediment, and the second, eight months later, using four sediment cores to study grain-size distribution in bottom sediments. Particle size analysis of superficial sediment shows that the sand in shallow depths is characterized by S-shaped curves, indicating a certain degree of agitation, possible transport by rip currents near the bottom and hyperbolic curves illustrating heterogeneity of sand stock. The sediments settle in a relatively calm environment. Along the bay…

TunisiaGeochemistryCore sediment010501 environmental sciences010502 geochemistry & geophysics01 natural sciencesCoastal sediment dynamics[ SDE ] Environmental Sciences14. Life underwaterGeomorphologySedimentary budgetRip current0105 earth and related environmental sciencesEarth-Surface ProcessesMineralsTerrigenous sedimentSedimentGeologyLongshore drift13. Climate action[SDE]Environmental SciencesHydrodynamicsSedimentary rockNortheasternSediment transportBayGeology
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Aportaciones documentales sobre cruces de orfebrería valencianas. Siglos XIV y XV

2020

The article intends to make a contribution of new documentary references, from the notarial funds of the Valencian archives, in which news about parish crosses and Lignum Crucis from the silversmith center of Valencia during the fourteenth and fifteenth centuries are collected. The importance of these typologies lies in being the main elements of Christian worship, so it was an essential piece in each parish that allowed the provision in them of models of varied typology and functionality; for that reason they are conserved from altar crosses, cross-shaped reliquaries ?known as Lignum Crucis or Veracruz ?to processional crosses, larger and representative of the parish community to which it …

UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASPere Capellades0211-5808 9678 Archivo de arte valenciano 564145 2020 101 7707977 Aportaciones documentales sobre cruces de orfebrería valencianas. Siglos XIV y XV Candela Garrigósfor that reason they are conserved from altar crossesin which news about parish crosses and Lignum Crucis from the silversmith center of Valencia during the fourteenth and fifteenth centuries are collected. The importance of these typologies lies in being the main elements of Christian worshiplarger and representative of the parish community to which it belongs. The result of this research has been the knowledge of works by important silversmiths such as Pere Bernesfrom the notarial funds of the Valencian archivesso it was an essential piece in each parish that allowed the provision in them of models of varied typology and functionalitycross-shaped reliquaries ?known as Lignum Crucis or Veracruz ?to processional crossesReyes The article intends to make a contribution of new documentary references:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]Francesc CetinaBertomeu Coscolláamong others. 63 78
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Exilic/Idyllic Shakespeare: Reiterating Pericles in Jacques Rivette’s Paris nous appartient

2015

Jacques Rivette’s Paris nous appartient (1961) is about a literature student, Anne Goupil, who becomes involved with a group of bohemians centering around the absent figure of Spanish musician, Juan. The film incorporates the attempt by theatre director Gérard Lenz – in many ways a simulacrum of Rivette himself – to stage Pericles, even though this is a play that he himself defines as “incoherent” and “unplayable.” This essay explores the significance of this incorporation, and shows how the reiterated, fragmentary rehearsals of this “unplayable” play are essential to an understanding of the (disjointed) logic of the film as well as the atmosphere of conspiracy it continually evokes. It als…

adaptation Pericles nouvelle vague Shakespeare Rivette ExileCultural StudiesLinguistics and LanguageShakespearean adaptation; nouvelle vague; Pericles; Exilic Shakespeare; Jacques Rivette; Paris nous appartient; Paris Belongs to Us; New Wave ShakespeareLiterature and Literary Theorynouvelle vagueJacques RivetteParis Belongs to UsNew Wave ShakespeareLanguage and LinguisticsPericlesExilic ShakespeareShakespearean adaptationParis nous appartientSederi
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Sedimentation in a fluvially infilling, barrier-bound estuary on a wave-dominated, microtidal coast: the Oueme River estuary, Benin, west Africa

2002

The Oueme River estuary is located on the seasonally humid tropical coast of Benin, west Africa. A striking feature of this microtidal estuary is the presence of a large sand barrier bounding a 120 km2 circular central basin, Lake Nokoue, that is being infilled by heterogeneous fluvial deposits supplied by a relatively large catchment (50 000 km2). Borehole cores from the lower estuary show basal Pleistocene lowstand alluvial sediments overlain by Holocene transgressive–highstand lagoonal mud and by transgressive to probably early highstand tidal inlet and flood-tidal delta sand deposited in association with non-preserved transgressive sand barriers. The change in estuary-mouth sedimentatio…

geographygeography.geographical_feature_categoryStratigraphyDrainage basinSedimentFluvialGeologyEstuarySedimentationInletLongshore driftOceanographyAlluviumGeologySedimentology
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Sedimentation in a tropical, microtidal, wave-dominated coastal-plain estuary

1996

The Mono estuary is an infilled, microtidal estuary located on the wave-dominated Bight of Benin coast which is subject to very strong eastward longshore drift. The estuarine fill comprises a thick unit of lagoonal mud deposited in a ‘central basin’between upland fluvial deposits and estuary-mouth wave-tide deposits. This lagoonal fill is capped by organic-rich tidal flat mud. In addition to tidal flat mud, the superficial facies overlying the ‘central basin’fill include remnants of spits resting on transgressive/washover sand, an estuary-mouth association of beach, shoreface, flood-tidal delta and tidal inlet deposits, and a thin sheet of fluvial sediments deposited over tidal flat mud. Af…

geographygeography.geographical_feature_categoryStratigraphyFluvialTidal irrigationGeologyEstuaryStrand plainLongshore driftSedimentary rockTidal prismProgradationGeomorphologyGeologySedimentology
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