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showing 10 items of 626 documents
L’elegia valenciana com a tòpic universal: la caiguda de València narrada des del Xarq al-Àndalus fins al romancer filipí
2016
Resum: Estudi de la formalització del concepte de València com a paradís perdut, des de la literatura àrab del Xarq al-Àndalus fins al romancer hispànic desenvolupat a l’arxipèlag filipí. S’hi analitza la conceptualització de l’elegia valenciana i el seu ús com a tòpic literari des de l’orient d’al-Àndalus fins a l’orient del món hispànic, explicant la formació del romancer filipí i la presència del Regne de València en les Lletres Filipines. S’hi estudien les elegies de la caiguda de la València islàmica a mans dels cristians, i com es formalitza una fascinació literària pel concepte de «València com a paradís», que s’exporta com a tòpic a una literatura asiàtica de base hispànica que té e…
Allostatic Load of Men and Women in Early Middle Age
2005
Abstract. The present longitudinal study investigated three aspects of allostatic load, a long-term negative consequence of physical responses to stress: (1) sex differences in allostatic load in early middle age, (2) associations between career stability history and allostatic load, and (3) relationships between allostatic load and health problems. Participants consisted of 62 men and 55 women from the ongoing Jyväskylä Longitudinal Study of Personality and Social Development, Finland. Allostatic load was the sum of eight parameters (dehydroepiandrosterone-sulfate, 12-h urinary norepinephrine, high-density lipoprotein, triglycerides, glycosylated hemoglobin, systolic and diastolic blood p…
La experiencia del combatiente en Sin novedad en el frente - 1929 de Erich Maria Remarque
2013
Estudio de la novela de E. M. Remarque Im Westen nichts Neues, fina descripción de sus experiencias como soldado en la Gran Guerra, que por su veracidad y profundo humanismo de gran calado ético y autocrítico se ha convertido en texto de referencia de las vivencias bélicas de aquella ¿generación perdida¿ tanto en Alemania como en el resto de países que participaron en la contienda. Palabras-clave: Guerra, vida en el frente, instrucción militar, visita y estancia en el hospital, el olvido y la memoria, el compañerismo y la amistad, la muerte de los animales, el espectáculo bélico, la sexualidad, los prisioneros, el otro como enemigo y como ser humano. Study E. M. Remarque¿s novel All Quiet i…
The Death of the Subject in David Lynch's Lost Highway and Mulholland Drive
2003
International audience; Quel est le sujet de ces deux films qui ont suscité de nombreuses interrogations auprès du public lors de leur sortie, questions portant notamment sur la signification de la diégèse ? Nous avançons que ce n'est pas à ce niveau-là que l'on doit chercher le sens des films de Lynch. En fait, la mort du personnage comme sujet va de pair avec l'absence d'une histoire ; l'évolution du cinéma de Lynch montre que, si sujet il y a, c'est du côté du spectateur qui tient désormais le rôle de l'enquêteur que tenait les personnages dans les œuvres antérieures (Blue Velvet et la série Twin Peaks). Le sujet lynchien apparaît alors un véritable objet dans une composition qui se refl…
Reproductive state and care giving in Stegodyphus (Araneae: Eresidae) and the implications for the evolution of sociality
2002
Abstract Cooperative brood care is a rare phenomenon in spiders and is restricted to a few social species, including three in the genus Stegodyphus. Brood care in Stegodyphus begins with regurgitation feeding followed by matriphagy: the young consume the body fluids of their mother causing her to die quickly. Whether such an extreme form of maternal care can become a communal task should depend on physiological or historical preconditions. I investigated whether femaleStegodyphus lineatus feed young or allow matriphagy according to their own reproductive state. Broods of young of two age classes (2 or 10 days after hatching) were isolated or fostered out to adult females that were unmated, …
The European wildcats (Felis silvestris silvestris) as reservoir hosts of Troglostrongylus brevior (Strongylida: Crenosomatidae) lungworms.
2014
The increasing reports of Troglostrongylus brevior lungworm in domestic cats from Italy and Spain raised questions on its factual distribution and on the role wildcats play as reservoirs of these parasites. Carcasses of 21 wildcats were collected in natural parks of southern Italy (i.e., Catania, Sicily n = 5 and Matera, Basilicata n = 16) and biometrically and genetically identified as Felis silvestris silvestris, but two as hybrids. Troglostrongylus brevior and Eucoleus aerophilus lungworms were found in 15 (71.4%) and 7 (33.3%) individuals, respectively, being five (23.8%) co-infected by the two species. Both lungworms showed an aggregated distribution in the host population, assessed by…
Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategies
2020
AbstractThere are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of …
Multiple actions of fenamates and other nonsteroidal anti-inflammatory drugs on GABAA receptors
2019
The nonsteroidal anti-inflammatory drug (NSAID) niflumic acid, a fenamate in structure, has many molecular targets, one of them being specific subtypes of the main inhibitory ligand-gated anion channel, the GABA(A) receptor. Here, we report on the effects of other fenamates and other classes of NSAIDs on brain picrotoxinin-sensitive GABA A receptors, using an autoradiographic assay with [S-35]TBPS as a ligand on mouse brain sections. We found that the other fenamates studied (flufenamic acid, meclofenamic acid, mefenamic acid and tolfenamic acid) affected the autoradiographic signal at low micromolar concentrations in a facilitatory-like allosteric fashion, i.e., without having affinity to …
Cooperative Transition in the Conformation of 24-Mer Tarantula Hemocyanin upon Oxygen Binding
2005
Hemocyanins are large respiratory proteins of arthropods and mollusks, which bind oxygen with very high cooperativity. Here, we investigated the relationship between oxygen binding and structural changes of the 24-mer tarantula hemocyanin. Oxygen binding of the hemocyanin was detected following the fluorescence intensity of the intrinsic tryptophans. Under the same conditions, structural changes were monitored by the non-covalently bound fluorescence probe Prodan (6-propionyl-2-(dimethylamino)-naphthalene), which is very sensitive to its surroundings. Upon oxygen binding of the hemocyanin a red shift of 5 nm in the emission maximum of the label was observed. A comparison of oxygen binding c…
Neuroprotective action of diazepam at very low and moderate doses in Alzheimer's disease model rats
2018
Abstract Early manifestations of Alzheimer's disease (AD) include neuroinflammation, disrupted neurotransmission and cognitive deficits. Impairment of the GABAergic system is essentially involved in the pathogenesis of AD. Traditionally, agonists of GABAA receptors at doses above 1 mg/kg are known to possess memory impairing effects. However, we have previously found that GABAA receptor GABA site ligand muscimol at very low doses acted contrary – enhanced spatial learning/memory, as well as prevented neuroinflammation and augmented neurotransmission in AD model rats. Therefore, in the present study we focused on the assessment of the effects of non-sedative – very low (0.05 mg/kg) and moder…