Search results for "Lp(a)"

Reflections on civil culpability and accountability in the destabilization of financial institutions

2010

PurposeThe purpose of this paper is to try and trace a new itinerary in the matter of the destabilization of financial institutions, i.e. the identification of a catalogue of measures that private law can offer in order to make sure that all unlawful initiatives resulting in the loss of credibility of financial markets and prejudice to the public at large do not escape the imposition of all possible liabilities.Design/methodology/approachThe matter here applied consists of the recourse to a number of experiences deriving from European legal systems that have tackled the phenomenon of unlawful attacks on the integrity of the financial markets through individual or organized acts. This compar…

Cartels Uncovered

2018

How many cartels are there? The answer is important in assessing the efficiency of competition policy. We present a Hidden Markov Model that answers the question, taking into account that often we do not know whether a cartel exists in an industry or not. Our model identifies key policy parameters from data generated under different competition policy regimes and may be used with time-series or panel data. We take the model to data from a period of legal cartels - Finnish manufacturing industries 1951 - 1990. Our estimates suggest that by the end of the period, almost all industries were cartelized.

Fractura social y ciudadana

2005

Matemātika

1997

Cis-epistasis at the LPA locus and risk of cardiovascular diseases.

2022

AIMS Coronary artery disease (CAD) has a strong genetic predisposition. However, despite substantial discoveries made by genome-wide association studies (GWAS), a large proportion of heritability awaits identification. Non-additive genetic-effects might be responsible for part of the unaccounted genetic variance. Here we attempted a proof-of-concept study to identify non-additive genetic effects, namely epistatic interactions, associated with CAD. METHODS AND RESULTS We tested for epistatic interactions in ten CAD case-control studies and UK Biobank with focus on 8,068 SNPs at 56 loci with known associations with CAD risk. We identified a SNP pair located in cis at the LPA locus, rs1800769 …

CALPAIN ACTIVITY MAINTAINS GOOD HEALTH OF CENTENARIAN T CELLS; SUMMARY OF THE CALPACENT PROJECT

2017

Causes of aging-associated deterioration of human immunity, and the reasons why the immune system of the oldest old individuals (centenarians) is relatively robust, remain moot. Intracellular proteolysis system of two proteases – µ- and m-calpain – and their inhibitor – calpastatin (the calpain-calpastatin system (CCS)) - is active in resting human peripheral blood T cells, participating in maintenance of their readiness to proliferate and secrete cytokines in response to stimulation. The amounts of the CCS proteins decrease in resting T lymphocytes of healthy elderly, only to return in the centenarians to those levels seen in the young individuals. We compared the calpain activities and th…

Childhood Sports Participation Is Associated With Health-Related Quality of Life in Young Men: A Retrospective Cross-Sectional Study

2021

The aim of the study was to examine whether sports participation (SP), engagement in competitive sports (CS) and the type of sport undertaken at the age of 12 are associated with the physical and the mental components of health-related quality of life (HRQoL) in young adulthood. The data were collected using questionnaires prior to a compulsory military refresher training course in Finland. The sample consisted of 784 men (mean age 26 years). HRQoL was measured with RAND 36 and childhood sports participation with a series of questions. Data were analysed with logistic regression. Higher frequency of SP, participation in district level CS, performing team, endurance or extreme sports and pla…

Godu telpas Latvijas viensētās

2017

Novērtēt atstāto un bieži vien degradējušos viensētu mantojumu un rast iespēju atdzimt jaunai funkcijai ir mūsdienu aktualitāte. Tā saglabājot vēstures liecības un panākot to attīstību. Godu telpas izveide vēsturiskā Latvijas viensētas saimniecības ēkā ir radošs veids kā atklāt un papildināt šo ēku unikalitāti un šarmu. Šī bakalaura darba galvenais mērķis ir godu telpas interjera dizaina projekta izveide Latvijas viensētā. Darba uzdevumi ir veikt teorētiskās literatūras un saistošo dokumentu analīzi par latviešu īpašumu un dzīvesvietu, Latvijas viensētām, godu tradīcijām senatnē un mūsdienās. Veikt salīdzinošo pētījumu par Latvijas viensētu godu telpu interjera izveides principu īstenošanu.…

Identification of GPR23/LPA4 as a candidate G protein-coupled receptor for Guanosine

2012

Prevalence of Levator Ani Defects in Urogynecological Patients

2016

Introduction: Defects of the levator ani muscle complex could represent a pathophysiological link between vaginal birth trauma and urogynecological symptoms many years later. The aim of our study was to determine the prevalence of levator ani muscle defects using 3D or 4D ultrasound and palpation in urogynecological patients. Material and Methods: Urogynecological patients were retrospectively investigated using 3D or 4D ultrasound. Clinical examination consisted of palpation and 3D or 4D imaging of the levator ani muscle. Results: A total of 319 women were included in the analysis. Mean age was 64.9 years, average parity was 2.1. Stress incontinence was present in 50.8 %, overactive bladde…