Search results for "Lua"
showing 10 items of 3286 documents
De novo 13q deletions in two patients with mild anorectal malformations as part of VATER/VACTERL and VATER/VACTERL-like association and analysis of E…
2013
Item does not contain fulltext Anorectal malformations (ARMs) comprise a broad spectrum of conditions ranging from mild anal anomalies to complex cloacal malformations. In 40-50% of cases, ARM occurs within the context of defined genetic syndromes or complex multiple congenital anomalies, such as VATER/VACTERL (vertebral defects [V], ARMs [A], cardiac defects [C], tracheoesophageal fistula with or without esophageal atresia [TE], renal malformations [R], and limb defects [L]) association. Here, we report the identification of deletions at chromosome 13q using single nucleotide polymorphism-based array analysis in two patients with mild ARM as part of VATER/VACTERL and VATER/VACTERL-like ass…
Assessment of a reconciliation and information programme for heart transplant patients
2010
Abstract Introduction The objective is to assess a pharmaceutical care programme for heart transplant patients upon patient admission and discharge. Material and methods Observational study of heart transplant patients, performed during the first quarter of 2007. Upon admission, the patient was interviewed regarding home treatments, adherence, allergies, and adverse effects, his/her prescriptions were compared with the last discharge report (drug reconciliation). At time of discharge, treatment was checked against the last hospital prescription (reconciliation) and an informative report was drawn up and personally delivered to the patient. Subsequently, a satisfaction questionnaire was carr…
A "grande política"
2015
Resumo Este artigo oferece uma discussão sobre o legado crítico em torno da noção de grande política na obra de Nietzsche, questão que foi dominada por três posições: 1) Nietzsche é reduzido a um ironista subjetivista, não se atribuindo a ele nenhuma (ou pouca) relevância na teoria política; 2) ou bem é estigmatizado como precursor intelectual dos totalitarismos políticos; 3) ou bem pode apresentar-se como um genuíno pensador político, para além dos totalitarismos e capaz de fecundar algumas concepções democráticas da vida política. Nesse último aspecto, apesar das críticas de Nietzsche à modernidade e à democracia, é possível vê que sua obra defende a noção de uma democracia radical, dado …
Semiquantitative assessment of pre-core stop-codon mutant and wildtype hepatitis B virus during the course of chronic hepatitis B using a new PCR-bas…
1996
In most patients with chronic hepatitis B positive for antibodies (anti-HBe) to HBe antigen (HBeAg), a pre-core mutant hepatitis B virus (HBV) with a point-mutation at nt. 1896 can be isolated. Clinical significance of the mutant virus in chronic hepatitis B is not proven yet, and screening of large numbers of sera during different clinical courses of numerous patients is necessary. We therefore aimed to develop a fast and reliable assay, that allows to discriminate wildtype from nt. 1896 G-->A mutant HBV and to determine the ratio of mutant and wildtype HBV in patients' sera. A mutation specific polymerase chain reaction (ms PCR) with new primers served to distinguish nt. 1896 G-->A mutant…
Direct acting antivirals after successful treatment of early hepatocellular carcinoma improve survival in HCV-cirrhotic patients
2019
Background & aims: The effectiveness of direct-acting antivirals (DAAs) against hepatitis C virus (HCV) after successful treatment of early hepatocellular carcinoma (HCC) has been studied extensively. However, the benefit in terms of overall survival (OS) remains to be conclusively demonstrated. The aim of this study was to assess the impact of DAAs on OS, HCC recurrence, and hepatic decompensation. Methods: We enrolled prospectively 163 consecutive patients with HCV-related cirrhosis and at first diagnosis of early Barcelona Clinic Liver Cancer (BCLC) 0/A HCC who had achieved a complete radiologic response after curative resection or ablation, subsequently treated with DAAs. DAA-untrea…
Pelvic girdle pain affects the whole life—A qualitative interview study in Norway on women’s experiences with pelvic girdle pain after delivery
2014
Background The aim of this study was to explore how pelvic girdle pain after delivery influences women’s daily life in Norway. Knowledge about living with post-partum pelvic girdle pain is lacking. Method A phenomenological–hermeneutical design with qualitative semi-structured interviews was used. A strategic selection procedure was chosen to recruit participants from physiotherapy clinics and a regional hospital in Norway. Five women with clinically verified pelvic girdle pain after delivery were included. Data were imported into NVivo9 and analysed in three steps: naïve reading, structural analysis and comprehensive understanding of the text. Results Three themes influencing the women’s d…
A Sequential Quadratic Programming Method for Volatility Estimation in Option Pricing
2006
Our goal is to identify the volatility function in Dupire's equation from given option prices. Following an optimal control approach in a Lagrangian framework, we propose a globalized sequential quadratic programming (SQP) algorithm with a modified Hessian - to ensure that every SQP step is a descent direction - and implement a line search strategy. In each level of the SQP method a linear-quadratic optimal control problem with box constraints is solved by a primal-dual active set strategy. This guarantees L^1 constraints for the volatility, in particular assuring its positivity. The proposed algorithm is founded on a thorough first- and second-order optimality analysis. We prove the existe…
Propiedades psicométricas del Inventario Breve de Síntomas-18 en una muestra heterogénea de pacientes de cáncer adulto
2019
espanolResumen El Inventario Breve de Sintomas-18 (BSI-18) es un instrumento de cribado ampliamente utilizado para evaluar distres emocional (GSI) y tres tipos de sintomas: ansiedad, depresion, y somatizacion. Este trabajo estudia la estructura factorial del BSI-18, utilizando analisis factorial confirmatorio (AFC), su fiabilidad y validez convergente, asi como su invarianza factorial a traves del sexo. Una muestra de 1183 pacientes de cancer completo el BSI 18 y la lista de problemas de la NCCN. Los modelos jerarquicos de tres y cuatro factores proporcionaron ajustes adecuados y similares. Sin embargo, el modelo de tres factores (propuesta teorica) fue seleccionado por razones metodologica…
High-energy devices in different surgical settings: lessons learnt from a full health technology assessment report developed by SICE (Società Italian…
2022
Background The present paper aims at evaluating the potential benefits of high-energy devices (HEDs) in the Italian surgical practice, defining the comparative efficacy and safety profiles, as well as the potential economic and organizational advantages for hospitals and patients, with respect to standard monopolar or bipolar devices. Methods A Health Technology Assessment was conducted in 2021 assuming the hospital perspective, comparing HEDs and standard monopolar/bipolar devices, within eleven surgical settings: appendectomy, hepatic resections, colorectal resections, cholecystectomy, splenectomy, hemorrhoidectomy, thyroidectomy, esophago-gastrectomy, breast surgery, adrenalectomy, and p…
Competency Research in Higher Education: Conceptual and Methodological Challenges and Perspectives for Future Interdisciplinary Research
2015
In recent years, an increasing number of research projects have been dedicated to competency assessment not only in school and vocational education, but also in higher education (Blomeke, Zlatkin-T...