Search results for "Lua"

showing 10 items of 3286 documents

Efficient virtual screening using multiple protein conformations described as negative images of the ligand-binding site.

2010

The protein structure-based virtual screening is typically accomplished using a molecular docking procedure. However, docking is a fairly slow process that is limited by the available scoring functions that cannot reliably distinguish between active and inactive ligands. In contrast, the ligand-based screening methods that are based on shape similarity identify the active ligands with high accuracy. Here, we show that the usage of negative images of the ligand-binding site, together with shape comparison tools, which are typically used in ligand-based virtual screening, improve the discrimination of active molecules from inactives. In contrast to ligand-based shape comparison, the negative …

Models MolecularVirtual screeningBinding SitesChemistryProtein ConformationGeneral Chemical EngineeringDrug Evaluation PreclinicalProteinsHydrogen BondingGeneral ChemistryComputational biologyLibrary and Information SciencesLigandsComputer Science ApplicationsUser-Computer InterfaceProtein structureBiochemistryROC CurveDocking (molecular)Computer GraphicsBinding siteDatabases ProteinSoftwareProtein BindingJournal of chemical information and modeling
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Savoir évaluer les compétences développées par les élèves : quels outils à la disposition du chercheur en éducation ?

2008

08099; Cet article porte sur la structure et l'évolution des compétences développées par les élèves au cours de l'école élémentaire. A partir d'analyses menées sur les données de panel du ministère de l'Education nationale, le questionnement général repose sur une mesure originale des compétences, basée sur des modèles structuraux. Il comporte deux aspects complémentaires. Le premier concerne la transversalité des apprentissages qui s'inscrivent dans une logique d'interdépendance. La maîtrise d'une compétence peut être ainsi fortement liée à la maîtrise d'autres compétences appartenant, soit à un même domaine d'acquisition, soit à des domaines différents ; la notion de bloc de compétences e…

Modèle structural[SHS.EDU]Humanities and Social Sciences/EducationEnseignement élementaire[SHS.EDU] Humanities and Social Sciences/EducationElève[ SHS.EDU ] Humanities and Social Sciences/EducationCompétenceEvaluation des compétences
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Quality of life after upper third molar removal: a prospective longitudinal study

2017

Background Third molar extraction is a very common procedure in Dentistry. The aim of this study was to evaluate the quality of life (QoL) and satisfaction of patients undergoing extraction of an upper third molar under local anesthesia. A second objective was to describe the evolution of self-reported pain measured in a visual analogue scale (VAS) in the 7 days after surgery and its relationship with pre- and intraoperative factors. Material and Methods A prospective longitudinal cohort study was made. Fifty-five patients received a questionnaire assessing social and working isolation, eating and speaking ability, diet modifications, sleep impairment, physical appearance, discomfort at sut…

MolarAdultMaleQuality of lifeLongitudinal studyWisdom toothVisual analogue scaleDentistryOdontologia03 medical and health sciencesDiagnostic Self Evaluation0302 clinical medicinePatient satisfactionQuality of lifeMedicineHumansTeeth extractionLocal anesthesiaLongitudinal StudiesProspective Studies030223 otorhinolaryngologyProspective cohort studyGeneral DentistryPain MeasurementExtracció dentalPain Postoperativebusiness.industryResearchQueixal del seny030206 dentistry:CIENCIAS MÉDICAS [UNESCO]OtorhinolaryngologyPatient SatisfactionQualitat de vidaDentistryTooth ExtractionUNESCO::CIENCIAS MÉDICASQuality of LifeSurgeryFemaleMolar ThirdOral SurgerybusinessComplication
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Comparative evaluation of shear bond strength of three flowable compomers on enamel of primary teeth: An in-vitro study

2015

Background: The aim of the present study was to determine Shear bond strength (SBS) of different flowable compomers on the enamel surface of primary teeth. The null hypothesis to be tested was that none of the flowable compomer would differ significantly from the other two with respect to SBS. As a result, the tested materials that have the easiest application on child patient is preferred. Material and Methods: Sixty newly extracted non carious primary molars were selected. The buccal surface was cleaned and polished to obtain a flat enamel surface. The specimens were randomly divided into three groups of 20 teeth each, based on the flowable compomers applied, as follows: group I: Dyract F…

MolarGroup iiDentistryOdontología01 natural sciencesOperative Dentistry and EndodonticsComparative evaluation03 medical and health sciences0302 clinical medicinestomatognathic systemIn vitro studyGeneral DentistryEnamel paintChemistrybusiness.industryResearch010401 analytical chemistrySignificant differenceShear bond strength030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludShear bond0104 chemical sciencesPrimary teethstomatognathic diseasesvisual_artUNESCO::CIENCIAS MÉDICASvisual_art.visual_art_mediumbusinessFlowable compomer
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A comparative evaluation between cheiloscopic patterns and the permanent molar relationships to predict the future malocclusions

2019

Background To assess the correlation between different cheiloscopic patterns with the permanent molar relationships. Material and methods 300 children who are 14-16 years old with completely erupted 2nd permanent molars upto occlusal table were recruited and the pattern of molar terminal plane was recorded in the proforma. Lip prints of these subjects were recorded with lipstick-cellophane method and middle 10mm of lower lip was analysed for the lip print pattern as suggested by Sivapathasundharam et al. The pattern were classified based on Tsuchihashi and Suzuki classification. Results Type II (branched) pattern was the most predominant cheiloscopic pattern. The predominant patterns which …

MolarOrthodonticsResearchLower lipMolar relationshipOrthodonticsBiology:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseComparative evaluationSample size determinationUNESCO::CIENCIAS MÉDICASReticular connective tissuemedicineMalocclusionDermatoglyphicsGeneral DentistryJournal of Clinical and Experimental Dentistry
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An in vivo comparative study of two apex locators

1994

Two different electronic apex locators were used before extraction to determine working length in 116 root canals belonging to 34 molars. The results were then compared with postextraction working length measurements. The determinations were made before and after eliminating the canal contents and drying the interior. The results showed that 84.8% and 79.3% of the Odometer, and 89.6% and 88.7% of the Endocater readings for dry and nondry canals, respectively, occurred within the two 0.5-mm intervals closest to the apical constriction.

Molarbusiness.industryReproducibility of ResultsWaterDentistryApical constrictionMolarRoot Canal TherapyApex (geometry)Evaluation Studies as TopicHumansOdontometryDental Pulp CavityTooth RootbusinessGeneral DentistryMathematicsJournal of Endodontics
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Measurement uncertainty impact on simplified load flow analysis in MV smart grids

2018

This work is focused on the measurement uncertainty impact on load flow analysis in medium voltage (MV) distribution networks. In more detail, the paper presents the uncertainty evaluation of a simplified load flow algorithm, which is based on the load power measurements at each secondary substation and one voltage measurement at the slack bus (i.e. the voltage at the MV bus bars of the primary substation). To reduce the costs of the monitoring system, the load flow algorithm makes use of LV load power measurements for all the substations except those of MV users, where MV transducers are usually already installed. The uncertainties on the algorithm input quantities (load powers and slack b…

MonitoringBusbar020209 energyMonte Carlo methodElectric load flowAdvanced metering infrastructure (AMI)02 engineering and technologySmart gridUncertainty evaluationElectric power system measurementPower quality analyzerSlack buspower system monitoringElectric power transmission networksControl theory0202 electrical engineering electronic engineering information engineeringpower quality analyzers (PQA)MedicinePower-flow studyload flow analysiSafety Risk Reliability and QualityInstrumentationbusiness.industryElectric power distributionPower (physics)Smart gridPower system measurementMeasurement uncertaintybusinessSettore ING-INF/07 - Misure Elettriche E ElettronicheVoltage
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Wild Sicilian Rosemary: Phytochemical and Morphological Screening and Antioxidant Activity Evaluation of Extracts and Essential Oils

2015

To identify the best biotypes, an extensive survey of Sicilian wild rosemary was carried out by collecting 57 samples from various sites, followed by taxonomic characterization from an agronomic perspective. All the biotypes collected were classified as Rosmarinus officinalis L. A cluster analysis based on the morphological characteristics of the plants allowed the division of the biotypes into seven main groups, although the characteristics examined were found to be highly similar and not area-dependent. Moreover, all samples were analyzed for their phytochemical content, applying an extraction protocol to obtain the nonvolatile components and hydrodistillation to collect the essential oil…

MonoterpenePhytochemicalsAntioxidant activity Cluster Analysis (CA) Essential oils Rosmarinus officinalis SicilyBioengineeringBiochemistryFlavonesAntioxidantsRosmarinusBorneolchemistry.chemical_compoundCamphorAntioxidant activityCluster Analysis (CA)Rosemary; Lamiaceae; Bioagronomic characterization; Essential oil; Polyphenols; Antioxidant activity.LedumOils VolatileWild rosemary biotyoeSicilyMolecular Biologychemistry.chemical_classificationChromatographyMolecular StructurebiologyPlant Extractsagronomic evaluationGeneral ChemistryGeneral Medicinebiology.organism_classificationSettore AGR/02 - Agronomia E Coltivazioni ErbaceePhytochemicalchemistryEssential oilsOfficinalisRosmarinus officinalisMolecular MedicineCamphenephytochemical evaluationChemistry & Biodiversity
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Yliopistotutkintojen määrän ennustaminen Bayes-mallilla

2017

Tämän tutkielman tarkoituksena on kehittää prediktiivinen malli, jolla ennustetaan Jyväskylän yliopiston matemaattis-luonnontieteellisessä tiedekunnassa lähivuosina suoritettavien luonnontieteiden kandidaatin ja filosofian maisterin tutkintojen lukumääriä. Mallin estimointiin käytettävä aineisto koostuu kolmesta osasta: vuosina 1996–2004 tiedekunnassa aloittaneet opiskelijat, vuosina 2005–2015 tiedekunnassa alemmasta korkeakoulututkinnosta aloittaneet opiskelijat ja vuosina 2005–2016 tiedekunnassa ylemmästä korkeakoulututkinnosta aloittaneet opiskelijat. Jokaiselle aineiston osalle sovitetaan omat toisistaan riippumattomat osamallit. Tutkintoennusteet saadaan ennustamalla aineistoon kuuluvi…

Monte Carlo -menetelmätopintojen kestoopiskeluaikaBayes-tilastotiedebayesilainen menetelmätilastomenetelmätkorkeakouluopiskeluopintojen keskeyttäminenMarkovin ketju Monte Carlo (MCMC)multinomiaalinen logistinen regressioyliopisto-opinnot
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Multiple-attribute decision support system based on fuzzy logic for performance assessment

2005

Abstract This paper deals with the problem of assessing the performance of a set of production units, simultaneously considering different kinds of information, yielded by a Data Envelopment Analysis, a qualitative data analysis and an expert assessment. The tool for integrating heterogeneous data is a model that applies fuzzy logic to decision support systems. The results obtained are a holistic performance assessment of each unit of the set and a ranking order of the units.

Multi-attribute decision aiding systemsDecision support systemInformation Systems and ManagementGeneral Computer ScienceComputer sciencemedicine.medical_treatmentDecision treeDecision support systemsManagement Science and Operations Researchcomputer.software_genreFuzzy logicIndustrial and Manufacturing EngineeringDEAmedicineData envelopment analysisExpert evaluationDecision engineeringEvidential reasoning approachIntelligent decision support systemDEA; Decision support systems; Expert evaluation; Fuzzy logic; Multi-attribute decision aiding systemsFuzzy logicModeling and SimulationData miningcomputerDecision analysis cycleDecision analysisEuropean Journal of Operational Research
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