Search results for "Lymphangioleiomyomatosis"

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Quantitative analysis of airway obstruction in lymphangioleiomyomatosis

2020

Lymphangioleiomyomatosis (LAM) is a rare, cystic lung disease with progressive pulmonary function loss caused by progressively proliferating LAM cells. The degree of airway obstruction has not been well investigated within the pathogenesis of LAM. Using a combination of ex vivo computed tomography (CT), microCT and histology, the site and nature of airway obstruction in LAM explant lungs was compared with matched control lungs (n=5 each). The total number of airways per generation, total airway counts, terminal bronchioles number and surface density were compared in LAM versus control. Ex vivo CT analysis demonstrated a reduced number of airways from generation 7 on (p<0.0001) in LAM compar…

Pulmonary and Respiratory MedicineLipopolysaccharidesPathologymedicine.medical_specialtyLung NeoplasmsPulmonary function testingPathogenesisOrphan Lung Diseases03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineMedicine and Health SciencesFLOW OBSTRUCTIONMedicineHumans030212 general & internal medicineLymphangioleiomyomatosisBronchiolesLungbusiness.industryHistologyOriginal ArticlesX-Ray MicrotomographyAirway obstructionrespiratory systemmedicine.disease133. Good healthrespiratory tract diseasesAirway Obstruction030228 respiratory systemPULMONARY LYMPHANGIOLEIOMYOMATOSISLymphangioleiomyomatosisHuman medicineAirwaybusinessQuantitative analysis (chemistry)Ex vivoCTThe European Respiratory Journal
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Angiomyolipomas are indicator lesions for sporadic lymphangioleiomyomatosis in women.

2008

medicine.medical_specialtyLung Neoplasmsbusiness.industryUrologyAngiomyolipomaMEDLINEmedicine.diseaseDermatologyKidney NeoplasmsLymphangioleiomyomatosismedicineHumansFemaleLymphangioleiomyomatosisbusinessEuropean urology
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