Search results for "M response"

Auditory Late Cortical Response and Speech Recognition in Digisonic Cochlear Implant Users

2002

Objective The purpose of the study was to test for differences in late electrically evoked auditory potentials between subjects exhibiting “good” versus “poor” speech recognition performances with their cochlear implants. Methods Late auditory evoked responses were measured in 30 subjects equipped with the Digisonic (MXM, Antibes, France) cochlear implant, 15 of whom had “good” speech recognition scores (i.e., more than 89% correct phoneme identification without lip reading). The 15 other subjects had poorer speech recognition scores (i.e., less than 85%). Results Differences in N1P2 amplitude, as well as P1, N1, and P2 latencies, and N1-P1 and N1-P2 latency intervals were tested. Wave P2 l…

New tools for detecting latent tuberculosis infection: evaluation of RD1-specific long-term response

2009

Abstract Background Interferon-gamma (IFN-γ) release assays (IGRAs) were designed to detect latent tuberculosis infection (LTBI). However, discrepancies were found between the tuberculin skin test (TST) and IGRAs results that cannot be attributed to prior Bacille Calmètte Guerin vaccinations. The aim of this study was to evaluate tools for improving LTBI diagnosis by analyzing the IFN-γ response to RD1 proteins in prolonged (long-term response) whole blood tests in those subjects resulting negative to assays such as QuantiFERON-TB Gold In tube (QFT-IT). Methods The study population included 106 healthy TST+ individuals with suspected LTBI (recent contact of smear-positive TB and homeless) c…

Gender-related differences in psychometric properties of WHO Disability Assessment Schedule 2.0

2019

Objective of this study was to investigate the gender-related differential item function of 12-item WHODAS 2.0 amongst patients with chronic musculoskeletal pain. This was a cross-sectional survey study among 1,988 patients at a university Physical and Rehabilitation Medicine outpatient clinic. To assess DIF, WHODAS 2.0 items were dichotomized as `none’ rated by respondents as `0’ versus `any limitation’ rated as `1,2,3 or 4’. The item response theory analysis was used to define discrimination and difficulty parameters of a questionnaire. The probit logistic regression was used to test uniformity of DIF between gender groups. The results of DIF analysis were presented and evaluated graphica…

Gene Expression Analyses during Spontaneous Reversal of Cardiomyopathy in Mice with Repressed Nuclear CUG-BP, Elav-Like Family (CELF) Activity in Hea…

2015

CUG-BP, Elav-like family (CELF) proteins regulate cell type- and developmental stage-specific alternative splicing in the heart. Repression of CELF-mediated splicing activity via expression of a nuclear dominant negative CELF protein in heart muscle was previously shown to induce dysregulation of alternative splicing, cardiac dysfunction, cardiac hypertrophy, and dilated cardiomyopathy in MHC-CELFΔ transgenic mice. A “mild” line of MHC-CELFΔ mice that expresses a lower level of the dominant negative protein exhibits cardiac dysfunction and myopathy at a young age, but spontaneously recovers normal cardiac function and heart size with age despite the persistence of splicing defects. To the b…

Prediction of the difficulty level in a standardized reading comprehension test: contributions from cognitive psychology and psychometrics

2013

This research seeks to identify possible predictors of the difficulty level of reading comprehension items used in a standardized psychometric test for university admission. Several potential predictors of difficulty were proposed, namely, propositional density, negations, grammatical structure, vocabulary difficulty, presence of enhancement elements (words highlighted typographically), item abstraction level and degree of similarity between correct option and relevant text to resolve the item. By Linear Logistic Test Model (Fisher, 1973) it was found that the number of propositions, the syntactic structure, and fundamentally, the presence of difficult words contributed to the prediction of…

MODELLING AND ANALYSING STUDENT DROPOUT IN COLOMBIAN HIGHER EDUCATION THROUGH POLICY AND PUBLIC MANAGEMENT

The complexity of the phenomenon of student dropout in higher education requires several modeling techniques. In this doctoral dissertation, findings of blending mathematical, statistical and Dynamic Performance Management as modelling techniques are presented to allow a deeper comprehension of Colombian student dropout in higher education.

Drought Monitoring In The Mediterranean Basin Using The Seviri/Msg Gpp Product (Mgpp)

2020

Recently, the Satellite Application Facility for Land Surface Analysis (LSA-SAF) has just released a new product that helps to characterize ecosystem processes, the 10-day LSA SAF GPP product from SEVIRI/MSG data (MGPP LSA-411). The GPP product is based on Monteith's concept, which models GPP as the product of the incoming photosynthetically active radiation (PAR), the fractional absorption of that flux $(\mathrm{f}_{APAR})$ and a light-use efficiency factor $(\varepsilon)$. Preliminary results on the use of the MGPP product in the assessment of ecosystem response to drought events are presented in this work for a short period of three years. A few sites located in the Mediterranean basin a…

Advantages of the Rasch measurement model in analysing educational tests:an applicator's reflection

2011

Educational achievement is a very important issue for parents, teachers, and the government. An accurate measurement plays a very important role in evaluating achievement fairly, and, therefore, analysis methods have been developed considerably in recent years. Education based on long-time learning processes forms a fruitful base for item tests, as it opens up possibilities to design a nearly unlimited number of items. There are several methods available to analyse such tests, but which method is the most useful and in which situation? The Rasch measurement from the Institute for Object Measurement (IOM) has pointed out to be the most useful in evaluating individual items and their function…

Wind turbine modeling using the bond graph

2011

Author's version of a chapter in the book: Proceedings of the IEEE International Symposium on Computer-Aided Control System Design. Also available from the publisher at: http://dx.doi.org/10.1109/CACSD.2011.6044572 This paper addresses the problem of bond graph methodology as a graphical approach for modeling wind turbine systems. In this case, we consider the modeling of a wind turbine system with individual pitch control scheme and the interaction with tower motions. Two different bond graph models are presented, one complex and one simplified. Furthermore, the purpose of this paper is not to validate a specific wind turbine model, but rather show the difference between modeling with a cl…

Improving a Measure of Mobility-Related Fatigue (The Mobility-Tiredness Scale) by Establishing Item Intensity

2013

Objectives To improve the construct validity of self‐reported fatigue by establishing a formal hierarchy of scale items and to determine whether such a hierarchy could be maintained across time (aged 75–80), sex, and nationality. Design Cohort study. Setting Two Nordic urban locations: Jyväskylä, Finland, and Glostrup, Denmark. Participants Baseline (1989/90) consisted of a random sample of citizens of Finland or Denmark born in 1914 (n = 837). At 5‐year follow‐up, excluding those lost to follow‐up and with baseline disability resulted in a sample of n = 690. Measurements The Mobility‐Tiredness (Mob‐T) Scale is a six‐item scale that requires subjects to self‐report on whether they become ti…