Search results for "Médical"
showing 10 items of 109 documents
Quel est le rôle du médecin et du pharmacien pour lever les freins encore existant à l’achat des médicaments génériques ? cas des médicaments hypolip…
2018
International audience
Singuliers généralistes. Sociologie de la médecine générale.
2010
International audience; Chacun de nous connaît un médecin généraliste, en qui il peut trouver un interlocuteur privilégié pour ses soucis de santé. En tant que groupe professionnel pourtant, les généralistes ont longtemps été peu considérés dans notre système de soins et restent méconnus : que sait-on des façons d'être généraliste ? de l'évolution de la profession ? Souvent passionnés par leur métier vécu comme un engagement personnel, les médecins généralistes sont-ils satisfaits de leurs conditions de travail et de leur place dans la société? À partir d'enquêtes récentes, des sociologues expliquent ce que sont et font les généralistes dans leur cabinet, ils analysent les "flous du métier"…
Review of current and “omics” methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms
2012
Ethnopharmacological relevance: The increasing use of traditional herbal medicines around the world requires more scientific evidence for their putative harmlessness. To this end, a plethora of methods exist, more or less satisfying. In this post-genome era, recent reviews are however scarce, not only on the use of new "omics" methods (transcriptomics, proteomics, metabonomics) for genotoxicity, teratogenicity, and nephrotoxicity assessment, but also on conventional ones. Methods: The present work aims (i) to review conventional methods used to assess genotoxicity, teratogenicity and nephrotoxicity of medicinal plants and mushrooms; (ii) to report recent progress in the use of "omics" techn…
Exceptional LAS Requests in Eurotransplant: Analysis of an 8-year Effort to Improve Lung Allocation for Precarious Patients
2020
PURPOSE: Following introduction of the lung allocation score (LAS) in 2011, Eurotransplant member centers can apply for an exceptional LAS (eLAS) if the calculated LAS insufficiently reflects the perceived transplant benefit for a patient, specifically in case of primary pulmonary hypertension group 1 and 4; combined lung+non-renal transplantation; rare diseases; or extracorporeal support. Each eLAS proposal is evaluated by a LAS Review Board, consisting of ≥3 lung transplant experts, which subsequently declines or approves the eLAS request in consensus of ≥3 votes. In case of a lower than accepted score, predefined business rules to assign LAS percentiles are used. METHODS: A retrospective…
An Open-Label Trial of 12-Week Simeprevir plus Peginterferon/Ribavirin (PR) in Treatment-Naïve Patients with Hepatitis C Virus (HCV) Genotype 1 (GT1)
2016
Background: Shortening duration of peginterferon-based HCV treatment reduces associated burden for patients. Primary objectives of this study were to assess the efficacy against the minimally acceptable response rate 12 weeks post-treatment (SVR12) and safety of simeprevir plus PR in treatment-naïve HCV GT1 patients treated for 12 weeks. Additional objectives included the investigation of potential associations of rapid viral response and baseline factors with SVR12. Methods: In this Phase III, open-label study in treatment-naïve HCV GT1 patients with F0-F2 fibrosis, patients with HCV-RNA 12-week regimen. Conclusions: Overall SVR12 rate (66%) was below the target of 80%, indicating that sho…
ESGAR consensus statement on liver MR imaging and clinical use of liver-specific contrast agents
2016
Objectives: To develop a consensus and provide updated recommendations on liver MR imaging and the clinical use of liver-specific contrast agents. Methods: The European Society of Gastrointestinal and Abdominal Radiology (ESGAR) formed a multinational European panel of experts, selected on the basis of a literature review and their leadership in the field of liver MR imaging. A modified Delphi process was adopted to draft a list of statements. Descriptive and Cronbach’s statistics were used to rate levels of agreement and internal reliability of the consensus. Results: Three Delphi rounds were conducted and 76 statements composed on MR technique (n = 17), clinical application of liver-speci…
Nomenclature et régulation médicalisée en médecine ambulatoire
1993
La récente négociation d'une nouvelle convention médicale pour la médecine libérale ne s'est pas effectuée sans difficulté. Le compromis qui a permis la signature de cette convention a retenu le principe d'une responsabilisation des médecins à travers un projet de maîtrise médicalisée. Ce projet conduit à réformer la nomenclature des actes en vigueur depuis 1972 et à définir de nouveaux référentiels de l'activité médicale qui serviraient de base à l'évaluation et à la maîtrise de cette activité. Toutefois; les objectifs d'un nouveau codage des actes ne sont pas clairement définis et l'efficacité d'une telle politique pour réduire les dépenses est loin d'être garantie.En effet, la réforme de…
Du surmenage structurel au basculement vers des troubles de santé : le cas des médecins généralistes exerçant en libéral
2022
Self treating in the moderne era
2013
In the modern era, self healing is to respond to situations created by medicine. Its effectiveness, its limits, its interventions, its practice, its tendency to medicalize existences, its inclusion in market economy are as many factors that interact with the self healing ability as attest the disruption of the patient's identity schema during interventions to repair physical trauma, chronic patient which depends on medicine, the medicalization of the aging. As well the task assigned to the modern man is to escape from enslavements, weathering effects, interferences generated by medical activities. In this sense, self healing is, on the one hand, to decrypt the aims of medicine and to determ…
Segmentation automatique et analyse de forme d'hippocampes humains dans l'étude de la maladie d'Alzheimer
2011
The aim of this thesis is to investigate the shape change in hippocampus due to the atrophy in Alzheimer’s disease (AD). To this end, specific algorithms and methodologies were developed to segment the hippocampus from structural magnetic resonance (MR) images and model variations in its shape. We use a multi-atlas based segmentation propagation approach for the segmentation of hippocampus which has been shown to obtain accurate parcellation of brain structures. We developed a supervised method to build a population specific atlas database, by propagating the parcellations from a smaller generic atlas database. Well segmented images are inspected and added to the set of atlases, such that t…