Search results for "MAC"
showing 10 items of 24950 documents
Per uno studio dei rapporti tra Sicilia e Malta: l’Immacolata d’argento della Chiesa di San Francesco di Naro
2011
El TDHA a través de narraciones ilustradas
2018
A través de esta propuesta pretendemos contribuir a la atención educativa de los alumnos de Educación Infantil que muestran un patrón conductual compatible con el diagnóstico del trastorno por déficit de atención con hiperactividad (TDAH), desde un enfoque preventivo, estimulando el análisis y la reflexión sobre determinados comportamientos mediante el género narrativo, por su valor educativo en esta etapa. Los alumnos de Educación Infantil se encuentran en un momento madurativo de fascinación natural hacia la escucha de narraciones. Presentamos una propuesta basada en narraciones ilustradas, ideadas y elaboradas por alumnos del Grado en Educación Infantil de la Universidad CEU Cardenal Her…
Narratives of children with high-functioning autism spectrum disorder: A meta-analysis
2016
Abstract Background The aim of this meta-analysis was to analyze the narrative performance of children and adolescents with high-functioning Autism Spectrum Disorders (ASD) in terms of microstructure, macrostructure and internal state language. Method A systematic literature search yielded 24 studies that met the predetermined inclusion criteria. Effect sizes for each study were calculated for eight variables and analyzed using a random effects model. Intellectual ability, age and type of narrative were considered as potential moderators. Results Results revealed that the children with ASD performed significantly worse than their peers on all the variables considered. Conclusions Findings a…
Ecological impacts of invasive signal crayfish in large boreal lakes
2012
Chemopreventive and Anticancer Role of Resveratrol against Oral Squamous Cell Carcinoma
2023
Oral squamous cell carcinoma (OSCC) is one of the most prevailing and aggressive head and neck cancers, featuring high morbidity and mortality. The available conventional treatments suffer from several adverse effects and are often inefficient in terms of their survival rates. Thus, seeking novel therapeutic agents and adjuvants is of the utmost importance for modern society. Natural polyphenolic compounds have recently emerged as promising chemopreventive and anticancer agents. Specifically, the natural compound resveratrol (RSV) has recently gained momentum for this purpose. RSV is useful for treating OSCC due to its antiproliferative, antimetastatic, and proapoptotic effects. Additionall…
La combustione HCCI mediante miscele di gas naturale e benzina: una prima esperienza sperimentale
2016
Si presentano in questo articolo i risultati di una sperimentazione volta a valutare la possibilità di effettuare una combustione HCCI (Homogeneous Charge Compression Ignition) stabile mediante l’impiego di miscele di gas naturale (GN) e benzina. La combustione HCCI ha ottime prerogative di basso impatto ambientale, ma la sua realizzazione pone qualche problema di stabilità al variare delle condizioni di carico richieste al motore: lo studio condotto mostra come l’impiego di miscele di GN e benzina, la cui composizione permette di variarne la resistenza all’autoaccensione, consente di ampliare il campo di funzionamento stabile della combustione HCCI. In the last decade the HCCI combustion h…
A New Simple Function for Combustion and Cyclic Variation Modeling in Supercharged Spark Ignition Engines
2022
Research in the field of Internal Combustion (IC) engines focuses on the drastic reduction of both pollutant and greenhouse gas emissions. A promising alternative to gasoline and diesel fuel is represented by the use of gaseous fuels, above all green hydrogen but also Natural Gas (NG). In previous works, the authors investigated the performance, efficiency, and emissions of a supercharged Spark Ignition (SI) engine fueled with mixtures of gasoline and natural gas; a detailed research involving the combustion process of this kind of fuel mixture has been previously performed and a lot of experimental data have been collected. Combustion modeling is a fundamental tool in the design and optimi…
Medicinal and aromatic plants in agricultural research, when considering criteria of multifunctionality and sustainability
2022
Over the last twenty years, agriculture has witnessed significant changes in terms of energy requirements, advanced technologies and practices. This is in response to the impacts of crop production on the climate and environment and increasing awareness of the importance of agricultural sustainability through organic farming. Agriculture encompasses complex production systems and certain aspects of multifunctionality and sustainability have become fundamental for these systems. Agricultural activity can provide various functions in agro-ecosystems, such as producing food, managing natural resources, and conserving landscape and plant biodiversity; contributing to the cultural, historical an…
Targeting GSK3 and Associated Signaling Pathways Involved in Cancer
2020
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine (S/T) protein kinase. Although GSK-3 originally was identified to have functions in regulation of glycogen synthase, it was subsequently determined to have roles in multiple normal biochemical processes as well as various disease conditions. GSK-3 is sometimes referred to as a moonlighting protein due to the multiple substrates and processes which it controls. Frequently, when GSK-3 phosphorylates proteins, they are targeted for degradation. GSK-3 is often considered a component of the PI3K/PTEN/AKT/GSK-3/mTORC1 pathway as GSK-3 is frequently phosphorylated by AKT which regulates its inactivation. AKT is often active in human cancer a…
In Silico Analysis of Microarray-Based Gene Expression Profiles Predicts Tumor Cell Response to Withanolides
2012
Withania somnifera (L.) Dunal (Indian ginseng, winter cherry, Solanaceae) is widely used in traditional medicine. Roots are either chewed or used to prepare beverages (aqueous decocts). The major secondary metabolites of Withania somnifera are the withanolides, which are C-28-steroidal lactone triterpenoids. Withania somnifera extracts exert chemopreventive and anticancer activities in vitro and in vivo. The aims of the present in silico study were, firstly, to investigate whether tumor cells develop cross-resistance between standard anticancer drugs and withanolides and, secondly, to elucidate the molecular determinants of sensitivity and resistance of tumor cells towards withanolides. Usi…