Search results for "MAC"

showing 10 items of 24950 documents

Environmental Enrichment During Adolescence Mitigates Cognitive Deficits and Alcohol Vulnerability due to Continuous and Intermittent Perinatal Alcoh…

2020

Perinatal alcohol exposure affects ontogenic neurodevelopment, causing physical and functional long-term abnormalities with limited treatment options. This study investigated long-term consequences of continuous and intermittent maternal alcohol drinking on behavioral readouts of cognitive function and alcohol vulnerability in the offspring. The effects of environmental enrichment (EE) during adolescence were also evaluated. Female rats underwent continuous alcohol drinking (CAD)—or intermittent alcohol drinking paradigm (IAD), along pregestation, gestation, and lactation periods—equivalent to the whole gestational period in humans. Male offspring were reared in standard conditions or EE un…

perinatal binge alcohol drinkingOffspringCognitive NeurosciencePhysiologyMorris water navigation taskAlcohollcsh:RC321-57103 medical and health scienceschemistry.chemical_compoundBehavioral Neuroscience0302 clinical medicineLactationMedicinelcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyOriginal Researchspatial memory.0303 health sciencesEnvironmental enrichmentbusiness.industryalcoholCognitive flexibilityCognitionalcohol vulnerabilityspatial memoryNeuropsychology and Physiological Psychologymedicine.anatomical_structurechemistrydeclarative memorySettore BIO/14 - Farmacologiaenvironmental enrichmentGestationperinatal continuous alcohol drinkingbusiness030217 neurology & neurosurgeryFrontiers in behavioral neuroscience
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Unitat 3 Notícies i Criteris de Noticiabilitat

2021

Aquesta unitat ofereix una definició de les fonts d'informació, tipologies i relació amb els i les periodistes. També destaca quins són els principis fonamentals que influeixen en què és o no notícia.

periodismeUNESCO::SOCIOLOGÍAcriteris de noticiabilitatfonts d'informació
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Unitat 2-Dret de la Informació i Deeontologia-GINF-Periodisme

2021

Aquesta unitat se centra en els principis legals i deontològics que influeixen en l'exercici de la tasca periodística

periodismeUNESCO::SOCIOLOGÍAdret de la informaciódeontologia
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Unitat 4-Les fonts informatives

2021

Aquesta unitat explica les característiques de les fonts d'informació, relació amb els i les periodistes i la identificació.

periodismeUNESCO::SOCIOLOGÍAfonts d'informació
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EMERGING ROLE OF ULTRASOUND IMAGING ASSOCIATED TO CLINICAL NEUROPHYSIOLOGY AS A SUPPLEMENTARY DIAGNOSTICS TECHNIQUE OF PERIPHERAL NERVES PATHOLOGIES:…

2013

PURPOSE: to show the relevance of peripheral nerve ultrasound imaging as a supplementary technique in a clinical neurophysiological evaluation. METHODS: peripheral nerves ultrasound (US) examination was performed in patients with a medical history of nerve entrapment and/or post-traumatic neuropathy but with clinical or neurophysiological unusual findings. A 10-18 MHz transducer was used. RESULTS: we recruited 50 patients with clinical evidence of peripheral neuropathies (25M, 25F): 24 median nerves, 1 anterior interosseous, 14 ulnar, 3 brachial plexus, 2 posterior interosseus, 1 superficial radial, 1 superficial peroneal and 4 common peroneal nerves. Overall 20/50 patients had a history of…

peripheral nerves ultrasound imaging clinical neurophysiologicalSettore BIO/14 - FarmacologiaSettore MED/37 - NeuroradiologiaSettore MED/26 - NeurologiaSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Diakonat stały w świetle Regulaminu formacji i posługi diakona stałego w diecezji opolskiej

2019

Działające w Opolu od siedmiu lat Studium Uzupełniające do Diakonatu Stałego przygotowało Regulamin formacji i posługi diakona stałego w diecezji opolskiej (Opole 2017). Jest on swoistym zbiorem opolskich doświadczeń związanych z formacją i posługą stałych diakonów. Powyższe przedłożenie jest formą ich opisania i usystematyzowania. Samo jednak widzenie problemu nie jest jego rozwiązaniem, dlatego podjęto też próbę pokazania, jak należy podchodzić do poszczególnych zagadnień, które Regulamin porządkuje.

permanent diaconateformacjadiakon stałyposługi diakonaformation ordinationświęceniaministry of deacon diakonaAteneum Kapłańskie
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Efficiency Improvement of Permanent-magnet Synchronous Motor Drives for Household Appliances

2011

This paper deals with some aspects of efficiency improvement of PMSMD (Permanent Magnet Synchronous Motor Drives). Particularly two aspects are focused: the control algorithm for the PMSMD, which allows to reduce the power losses of the electric drive without penalty on its dynamic performances and the optimization of an IPMSM (Interior Permanent Magnet Synchronous Motor) rotor configuration capable to increase the performances in terms of shaft torque production, limiting at the same time the rotor leakage flux. The loss minimization algorithm is here briefly analysed, a test bed for experimental validation is presented and the data are analysed. Experimental tests have been performed aimi…

permanent magnet machines and driveEfficiency improvementfinite element analysisSettore ING-IND/32 - Convertitori Macchine E Azionamenti Elettrici
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Buccal Thin Films as Potent Permeation Enhancers for Cytisine Transbuccal Delivery

2022

Cytisine (CYT) is a powerful anti-smoking compound which could greatly benefit from transbuccal delivery because of both its unfavorable pharmacokinetics after oral administration and its intrinsic ability to permeate the buccal mucosa. This work aims to design CYT-loaded buccal thin films suitable for transbuccal drug delivery due to its capability of promoting the interaction between CYT and the buccal membrane. The solvent casting method was employed to prepare several thin films combining various excipients such as matrixing polymers, mucoadhesion agents, plasticizers and other compounds as humectants and sweeteners, component ratios and solvents. A total of 36 compositions was prepared…

permeation enhancerdrug-membrane interactionbuccal filmSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoProcess Chemistry and Technologycytisinecytisine; buccal film; transmucosal drug delivery; drug-membrane interaction; permeability; mucoadhesion; permeation enhancer; ex vivo modelChemical Engineering (miscellaneous)Filtration and Separationpermeabilityex vivo modeltransmucosal drug deliverymucoadhesionMembranes; Volume 12; Issue 11; Pages: 1169
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Inulin-Based Polymeric Micelles Functionalized with Ocular Permeation Enhancers: Improvement of Dexamethasone Permeation/Penetration through Bovine C…

2021

Ophthalmic drug delivery is still a challenge due to the protective barriers of the eye. A common strategy to promote drug absorption is the use of ocular permeation enhancers, while an innovative approach is the use of polymeric micelles. In the present work, the two mentioned approaches were coupled by conjugating ocular permeation enhancers (PEG2000, carnitine, creatine, taurine) to an inulin-based co-polymer (INU-EDA-RA) in order to obtain self-assembling biopolymers with permeation enhancer properties for the hydrophobic drug dexamethasone (DEX). Inulin derivatives were properly synthetized, were found to expose about 2% mol/mol of enhancer molecules in the side chain, and resulted abl…

permeation enhancermicellesPEG2000InulinPharmaceutical SciencedexamethasoneMicelleocular drug deliveryArticlechemistry.chemical_compoundPharmacy and materia medicaSide chainEnhancerChromatographyinulinPEG<sub>2000</sub>Chemistrypermeation enhancerscarnitinePenetration (firestop)PermeationRS1-441creatineIonic strengthtaurineEx vivoPharmaceutics
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Non-Occupational Exposure to Pesticides: Experimental Approaches and Analytical Techniques (from 2019)

2021

© 2021 by the authors.

pesticide residuesNon occupationalenvironmental exposurePharmaceutical ScienceOrganic chemistryReview010501 environmental scienceshuman health01 natural sciencesGas Chromatography-Mass SpectrometryMass SpectrometryAnalytical ChemistryGlobal populationHuman healthQD241-441Environmental healthDrug DiscoveryPlaguicidesHealth Status IndicatorsHumansPesticidesPhysical and Theoretical ChemistrySolvent extractionestimated intakesChromatography High Pressure Liquid0105 earth and related environmental sciencesPesticide residueSolid Phase Extraction010401 analytical chemistryindirect estimationdirect estimationEnvironmental exposureQuímicaPesticide0104 chemical scienceswastewater-based epidemiologyChemistry (miscellaneous)Human exposureSolventsMolecular MedicineEnvironmental scienceMolecules
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