Search results for "MAC"
showing 10 items of 24950 documents
Synthesis and Biological Evaluation of a Multiantigenic Tn/TF-Containing Glycopeptide Mimic of the Tumor-Related MUC1 Glycoprotein
2006
Los bienes comunes en el pensamiento de Stefano Rodotà
2021
El trabajo se ha desarrollado en el marco del proyecto de investigación BICOM. Bienes comunes: articulación cívica y jurídica (CAMUAM, SI/PJI/2019- 00474), codirigido por Ricardo Cueva y Luis Lloredo. También se ha participado con el proyecto Vulnus (INV-IGU159- 2021).
Mandibular involvement of solitary plasmocytoma : a case report
2007
Plasma cell neoplasms (multiple myeloma, solitary plasmocytoma of bone and extra medullar plasmocytoma) are characterized by a monoclonal neoplastic proliferation of plasma cells. Solitary plasmocytoma of bone (SPB) is a localized form of them. SPB is most frequently seen in vertebrae and secondarily in long bones. Its presence in jaws is extremely rare and when it is seen, angulus and ramus mandible are most common sites of occurrence. Prognosis of SPB is worse than extra medullar plasmacytoma (EMP) and approximately 50% of SPB will transform to multiple myelom. A 76- year old woman consulted to our clinic with a chief complaint of slowly developed swelling in her mandible. She had an oper…
Elementos de resolución de problemas en primeras edades escolares con Bee-bot
2018
En este trabajo se presenta un estudio exploratorio sobre elementos de resolución de problemas puestos en juego por estudiantes de primeras edades escolares mientras resuelven tareas con el robot programable Bee-bot. En dichos problemas, los estudiantes deben secuenciar las instrucciones necesarias para que el robot recorra un camino desde un punto inicial a otro final. Se pretende observar y caracterizar actuaciones de tres parejas de estudiantes con el fin de determinar recursos heurísticos y procesos de gestión desarrollados durante la resolución de los problemas. Al ser un estudio exploratorio, se han seleccionado dos parejas de estudiantes del último curso de infantil y una pareja del …
Entry and processing of Borrelia burgdorferi pleomorphic forms
2015
Lymen borrelioosi on Suomessakin yleinen puutiaisten levittämä tauti. Borrelioosin ensimmäisiä oireita ovat muun muassa puutiaisen pureman ympärille muodostuva ihottuma, päänsärky, väsymys ja kuume. Myöhemmin tauti voi aiheuttaa nivel- tai sydäntulehduksen sekä neurologisia oireita. Borrelioosi on monessa suhteessa kiistanalainen tauti, sillä esimerkiksi sen hoidosta ja mahdollisesta kroonistumisesta on kaksi eriävää näkemystä. Taudin aiheuttaja on Borrelia burgdorferi -bakteeri (Bb). Bb pystyy välttelemään isännän immuunipuolustusta useilla eri mekanismeilla. Bakteeri on korkkiruuvinmuotoinen spirokeetta, mutta voi esiintyä myös epätyypillisinä muotoina, joihin kuuluu esimerkiksi pyöreä mu…
A DNA‐Encoded FRET Biosensor for Visualizing the Tension across Paxillin in Living Cells upon Shear Stress
2022
Paxillin is a potential participant in the direct intracellular force transmission which is considered as the foundation of cells sensing and responding to extracellular environment. However, the detection of tension across paxillin has not been achieved due to lacking microsized tools. Herein, a paxillin tension sensor (PaxTs) based on Fluorescence Resonance Energy Transfer (FRET) technique was constructed. PaxTs can be expressed and assembled to FA sites spontaneously to visualize the tension across paxillin with FRET efficiency of ~62.4% in living cells. The tension across paxillin was found to decrease upon shear stress, in which the membrane fluidity and contractility of actin acted as…
Combined Use of Structure Analysis, Studies of Molecular Association in Solution, and Molecular Modelling to Understand the Different Propensities of…
2021
The arrangement of hydroxyl groups in the benzene ring has a significant effect on the propensity of dihydroxybenzoic acids (diOHBAs) to form different solid phases when crystallized from solution. All six diOHBAs were categorized into distinctive groups according to the solid phases obtained when crystallized from selected solvents. A combined study using crystal structure and molecule electrostatic potential surface analysis, as well as an exploration of molecular association in solution using spectroscopic methods and molecular dynamics simulations were used to determine the possible mechanism of how the location of the phenolic hydroxyl groups affect the diversity of solid phases formed…
Advances in Nanoliposomes Production for Ferrous Sulfate Delivery
2020
In this study, a continuous bench scale apparatus based on microfluidic fluid dynamic principles was used in the production of ferrous sulfate-nanoliposomes for pharmaceutical/nutraceutical applications, optimizing their formulation with respect to the products already present on the market. After an evaluation of its fluid dynamic nature, the simil-microfluidic (SMF) apparatus was first used to study the effects of the adopted process parameters on vesicles dimensional features by using ultrasonic energy to enhance liposomes homogenization. Subsequently, iron-nanoliposomes were produced at different weight ratios of ferrous sulfate to the total formulation components (0.06, 0.035, 0.02, an…
Evaluation of the Behavior of Phenolic Compounds and Steviol Glycosides of Sonicated Strawberry Juice Sweetened with Stevia (Stevia rebaudiana Berton…
2019
In this study, the influence of stevia addition and sonication processing parameters on the phenolic content and profile as well as the steviol glycosides of strawberry juice-based samples was investigated. For this purpose, three matrices&mdash
The adaptations to tube-dwelling life of Propsilocerus akamusi (Diptera: Chironomidae) larvae and its eutrophication-tolerant mechanisms
2019
Propsilocerus akamusi (Diptera: Chironomidae) is a dominant macroinvertebrate species in many eutrophic lakes in subtropical and temperate zones. P. akamusi larvae can migrate deep into the sediment (>30 cm) during summer where is no oxygen. However, to our knowledge, the specific adaptive tactics of its tube-dwelling life (>30 cm) and underlying mechanisms why this species is favored by nutrient-rich lakes remain limited. With the understanding above-mentioned issues, we can provide important information for the development of sensitive biomonitoring. We examined monthly morphological dynamics and physiological adaptations of P. akamusi to anoxic conditions, and environmental relationships…