Search results for "MAC"

showing 10 items of 24950 documents

Kiusaamiskokemukset yhteisöön kiinnittymisen esteenä

2009

Artikkeli perustuu Puheviestinnän päivillä 25.9.2009 pidettyyn plenum-esitelmään Kiusaamiskokemukset yhteisöön kiinnittymisen esteenä.

sopeutuminenkiusaaminenPharmacology (medical)yhteisötEsitelmäPrologi
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Discovery of a new class of sortase a transpeptidase inhibitors to tackle gram-positive pathogens: 2-(2-phenylhydrazinylidene)alkanoic acids and rela…

2016

A FRET-based random screening assay was used to generate hit compounds as sortase A inhibitors that allowed us to identify ethyl 3-oxo-2-(2-phenylhydrazinylidene)butanoate as an example of a new class of sortase A inhibitors. Other analogues were generated by changing the ethoxycarbonyl function for a carboxy, cyano or amide group, or introducing substituents in the phenyl ring of the ester and acid derivatives. The most active derivative found was 3-oxo-2-(2-(3,4dichlorophenyl)hydrazinylidene)butanoic acid (2b), showing an IC50 value of 50 µM. For a preliminary assessment of their antivirulence properties the new derivatives were tested for their antibiofilm activity. The most active compo…

sortase A; biofilms; 2-(2-phenylhydrazinylidene)alkanoic acid derivatives; FRET0301 basic medicineStaphylococcus aureusStereochemistryPharmaceutical ScienceRelated derivativesmedicine.disease_causeSettore BIO/19 - Microbiologia Generale01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-441Inhibitory Concentration 5003 medical and health scienceschemistry.chemical_compound2-(2-phenylhydrazinylidene)alkanoic acid derivativeAnti-Infective AgentsBacterial Proteinslcsh:Organic chemistryStaphylococcus epidermidisAmideDrug DiscoveryStaphylococcus epidermidismedicineEnzyme InhibitorsPhysical and Theoretical ChemistryIC50Grambiology010405 organic chemistryChemistryBiofilmSortase AOrganic ChemistryBiofilmAminoacyltransferasesbiology.organism_classificationSettore CHIM/08 - Chimica Farmaceutica2-(2-phenylhydrazinylidene)alkanoic acid derivativesPhenylhydrazines0104 chemical sciencesCysteine Endopeptidases030104 developmental biologyChemistry (miscellaneous)Staphylococcus aureusSortase AFRETMolecular Medicinebiofilms
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Stakeholder salience for small businesses : a social proximity perspective

2017

This paper advances stakeholder salience theory from the viewpoint of small businesses. It is argued that the stakeholder salience process for small businesses is influenced by their local embeddedness, captured by the idea of social proximity, and characterised by multiple relationships that the owner-manager and stakeholders share beyond the business context. It is further stated that the ethics of care is a valuable ethical lens through which to understand social proximity in small businesses. The contribution of the study conceptualises how the perceived social proximity between local stakeholders and small business owner-managers influences managerial considerations of the legitimacy, …

sosiaalinen läheisyysINTERFIRM NETWORKSlocal embeddednessMEDIUM-SIZED ENTERPRISESpienyrityksetsidosryhmätSmall business05 social sciences06 humanities and the artsPublic relationssmall businessEthics of care5141 Sociology511 EconomicsetiikkaEconomics and EconometricsEmbeddednessethics of careFIRMS0603 philosophy ethics and religionStakeholder salienceArts and Humanities (miscellaneous)social proximity0502 economics and businessStakeholder analysisBusiness and International ManagementCSREMBEDDEDNESSLegitimacystakeholder relationsStakeholder relationsIDENTIFICATIONSalience (language)business.industryRESPONSIBILITYSMESLocal embeddednessSmall businessstakeholder saliencepaikallisuuseettisyysEthics of careGeneral Business Management and AccountingETHICAL ATTITUDESIDENTITYCorporate social responsibility060301 applied ethicsBusiness ethicsbusinessLaw050203 business & managementSocial proximity
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Understanding McDonald's Among the "World’s Most Ethical Companies"

2008

The animal welfare policies and related public communication initiatives of McDonald’s corporation are examined in the context of the organization being named as one of the world’s most ethical organizations. The result is a framework for understanding how McDonald’s and similar organizations could warrant the status of a most ethical company. Specifically, the narrative strength of the company’s articulation of an animal welfare policy and its ongoing promotion as a legitimizing strategy illustrate how McDonald’s might address the social and ethical issues it encounters through its operations and how its stakeholding publics are likely to respond. By maintaining narrative strength in commu…

sosiaalinen vastuueläimetsocial responsibilitylegitimacyMcDonald'seettisyysethicsanimal welfare
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Valutazione del profilo di rilascio e dell'attività biologica di sostanze attive veicolate mediante sistemi particellari a matrice lipidica

sostanze naturali.MADSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoSLNNLCnanoparticelle lipidiche
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Signal processing techniques for robust sound event recognition

2019

The computational analysis of acoustic scenes is today a topic of major interest, with a growing community focused on designing machines capable of identifying and understanding the sounds produced in our environment, similar to how humans perform this task. Although these domains have not reached the industrial popularity of other related audio domains, such as speech recognition or music analysis, applications designed to identify the occurrence of sounds in a given scenario are rapidly increasing. These applications are usually limited to a set of sound classes, which must be defined beforehand. In order to train sound classification models, representative sets of sound events are record…

sound event recognitionfeature selection:CIENCIAS TECNOLÓGICAS [UNESCO]audio classificationdeep learningUNESCO::CIENCIAS TECNOLÓGICASsupport vector machines
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Predictive models in assessment of macroinvertebrates in boreal rivers

2009

Jukka Aroviita tutki väitöskirjassaan jokien ja purojen biologisen tilan mittaamismenetelmiä. Aroviita osoitti, että ihmistoiminnan aiheuttamat biologiset muutokset voivat jäädä havaitsematta, jos eliöyhteisöjen luonnollista taustavaihtelua ei oteta kunnolla huomioon.- Tällöin vesistöjen saatetaan arvioida olevan paremmassa kunnossa kuin ne todellisuudessa ovatkaan. Muutosten tunnistamistarkkuuden tulisi olla mahdollisimman hyvä, sillä tila-arvioilla on myös juridisesti määräytyviä yhteiskunnallisia ja taloudellisia seuraamuksia, Aroviita toteaa. Vielä 1990-luvulla järvien ja jokien tilaa arvioitiin suurelta osin ihmisen näkökulmasta ja veden kemian perusteella. Nykylainsäädäntö edellyttää …

spatial scalebioassessmentpohjaeläimistöRIVPACSbiotic qualitytaxonomic completenessvirtavedetvertailuololähestymistapaennustavat mallitmacroinvertebratestypologystreamstypologiat
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SEMANTIC AND CONTEXTUAL APPROACH FOR THE RECOMMENDATION OF LEARNING MODULES IN MOBILITY

2012

International audience; Many researchers argue that mobile learning is just an adaptation of e-learning on mobile technology, but far from a simple extension of e-learning, m-learning raises original issues in technological and pedagogical terms. M-learning is usually based on the consideration of a context rich on information and interactions. The challenge of m-learning is therefore, not simply to transfer on mobile content designed primarily for e-learning. This concept implies that we must rethink the entire process of the learning experience in mobility to maximize its efficiency.

spatiotemporal contextmetaheuristics[ INFO.INFO-IU ] Computer Science [cs]/Ubiquitous Computing[INFO.INFO-IU] Computer Science [cs]/Ubiquitous Computing[INFO.INFO-LG] Computer Science [cs]/Machine Learning [cs.LG][ INFO.INFO-LG ] Computer Science [cs]/Machine Learning [cs.LG][INFO.INFO-IU]Computer Science [cs]/Ubiquitous Computing[INFO.INFO-MC]Computer Science [cs]/Mobile Computing[INFO.INFO-MC] Computer Science [cs]/Mobile Computing[INFO.INFO-LG]Computer Science [cs]/Machine Learning [cs.LG]learner's profile[ INFO.INFO-MC ] Computer Science [cs]/Mobile Computinglearner's profile.ontologym-learningRecommender system
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Recommender system for combination of learning elements in mobile environment

2012

5 pages; International audience; The paper presents an ongoing research about the development of a new recommender system dedicated to m-learning. This system is an extension of content based recommender system proposals. It's made of three levels architecture: 1/ a domain model describing the knowledge of teaching, 2/ a user model defining learner's profile and learning's context, 3/ an adaptation model containing rules and metaheuristics, which aims at combining learning modules. Our system takes into account the spatio-temporal context of the learners, the evolution of learner's profile and the dynamic adaptation of modules during the learning process in a mobile environment. The result …

spatiotemporal contextmetaheuristics[ INFO.INFO-IU ] Computer Science [cs]/Ubiquitous Computing[INFO.INFO-IU] Computer Science [cs]/Ubiquitous Computing[INFO.INFO-LG] Computer Science [cs]/Machine Learning [cs.LG][ INFO.INFO-LG ] Computer Science [cs]/Machine Learning [cs.LG][INFO.INFO-IU]Computer Science [cs]/Ubiquitous Computing[INFO.INFO-MC]Computer Science [cs]/Mobile Computing[INFO.INFO-MC] Computer Science [cs]/Mobile Computing[INFO.INFO-LG]Computer Science [cs]/Machine Learning [cs.LG]learner's profile[ INFO.INFO-MC ] Computer Science [cs]/Mobile Computingontologym-learningRecommender system
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The Dawn of the Human-Machine Era: A forecast of new and emerging language technologies

2021

New language technologies are coming, thanks to the huge and competing private investment fuelling rapid progress; we can either understand and foresee their effects, or be taken by surprise and spend our time trying to catch up. This report scketches out some transformative new technologies that are likely to fundamentally change our use of language. Some of these may feel unrealistically futuristic or far-fetched, but a central purpose of this report - and the wider LITHME network - is to illustrate that these are mostly just the logical development and maturation of technologies currently in prototype. But will everyone benefit from all these shiny new gadgets? Throughout this report we …

speaking through technologymachine learningDatavetenskap (datalogi)Computer SciencesComputer sciencelinguistic dataLanguage technologyhuman integrated speaking devicesSpeech technologychatbotsHuman–machine systemlanguage technologiesData science
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