Search results for "MACI"

showing 10 items of 2094 documents

Natural products for the treatment of Type 2 Diabetes Mellitus

2015

Type 2 diabetes mellitus is a metabolic disease characterized by persistent hyperglycemia. High blood sugar can produce long-term complications such as cardiovascular and renal disorders, retinopathy, and poor blood flow. Its development can be prevented or delayed in people with impaired glucose tolerance by implementing lifestyle changes or the use of therapeutic agents. Some of these drugs have been obtained from plants or have a microbial origin, such as galegine isolated from Galega officinalis, which has a great similarity to the antidiabetic drug metformin. Picnogenol, acarbose, miglitol, and voglibose are other antidiabetic products of natural origin. This review compiles the princi…

Blood GlucosePeroxisome Proliferator-Activated ReceptorsPharmaceutical ScienceMedical PlantsPharmacologyAnalytical ChemistryDrug DiscoveryGlucose homeostasisAcarboseClinical Trials as Topicdiabetesbiologyfood and beverages//purl.org/becyt/ford/3.1 [https]Medicina BásicaMolecular Medicine//purl.org/becyt/ford/3 [https]medicine.drugFarmacología y Farmaciamedicine.medical_specialtyCIENCIAS MÉDICAS Y DE LA SALUDBlood sugarfoodInternal medicineYerba-mateVoglibosemedicineDiabetes MellitusHumansHypoglycemic AgentsGlycoside Hydrolase InhibitorsClinical TrialsPharmacologyBiological Productsclinical trialsPlants Medicinalantidiabeticbusiness.industryMiglitolOrganic ChemistryType 2 Diabetes Mellitusalpha-Glucosidasesbiology.organism_classificationfood.foodEndocrinologyDiabetes Mellitus Type 2Complementary and alternative medicineAntidiabeticHyperglycemiaCiencias MédicasGalega officinalisalpha-Amylasesbusinessmedicinal plants
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Antecedentes de las consultas de boca-oído online sobre hoteles

2017

Las consultas online sobre productos y servicios antes de la compra han recibido menor atención en la literatura que la generación de comentarios después de la experiencia. Nuestro trabajo aborda, por tanto, el estudio de la conducta de boca-oído online desde la perspectiva del receptor. El objetivo es investigar las variables que contribuyen en la adopción de boca-oído online para tomar la decisión de elección de un hotel. Para ello, se analiza la cadena de relaciones “motivaciones→intención de consultar→volumen→adopción”, considerando tres tipos de motivaciones: conveniencia, riesgo y sociales. Con una muestra de 393 huéspedes de hoteles de 3, 4 y 5 estrellas y a partir de un modelo de ec…

Boca-oído onlineInformation adoptionVolumeVolumenHotelesMotivacionesAdopción de informaciónMotivationsOnline word-of-mouthHotels
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"Sempre m'ha faltat València i em continua faltant"

2008

BolsaSociedadMúnichVidal-Beneyto JoséDemocráticaBIOGRAFÍAPolíticaContubernioEconomíaBrosetaAntifranquismoAcciones: Acciones de una vida: Sociología y nuevas formacionesBanco de la ExportaciónResistencia críticaComplutenseMadridCarcaixentRepublicanosFinanzasFranquismoAcciones: Actividades Económicas: Financieras-BancariasPaís ValencianoCEISAJOSÉ VIDAL-BENEYTOPolítica valencianaFusterPartido ComunistaLuchaValenciaGranellIdeologíaEntrevistasEuropaComercioAcciones: Acciones de una vida: Democracia (I)ParísSociología
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La circulation des objets métalliques à l'âge du Bronze entre Rhône et Saône: utilisation d'une transformation cartographique linéaire

2006

In order to gain a better understanding of circulation flows of metal objects during the Bronze Age, and move beyond traditional distribution maps of archaeological discoveries, the authors propose a more quantitative and concise method of graphic representation, namely cartographic linear transformation. The value of the method was tested on the Saône-Rhône axis. Bronze axes, swords and daggers were recorded along a 50 km strip either side of the river axis, in order to estimate the frequency and mass of objects in “circulation”.

Bronze AgeCartography[SHS.STAT]Humanities and Social Sciences/Methods and statistics[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryCartographieRhôneArqueologíaCartographic linear transformationArchaeologyAge du Bronze[ SHS.ARCHEO ] Humanities and Social Sciences/Archaeology and Prehistory[SHS.STAT] Humanities and Social Sciences/Methods and statisticscirculationTransformación cartográfica linearSaôneCartografíaRódanoEdad del Bronce[ SHS.STAT ] Humanities and Social Sciences/Methods and statisticstransformation cartographique
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Las armas de la falsedad masiva / y 2

2004

BushGUERRA DEL GOLFOImposturas mediáticasVidal-Beneyto JoséEstados UnidosMedios de comunicaciónFalsedad masivaIrakBombarderosCOMUNICACIÓNMontajeCollin PowellFalsedad en masaPublicaciones: Obra periodística: Columnas y artículos de opiniónArmasKuwaitCongresoNorteaméricaSadam HuseinInvestigaciónDesinformaciónViolaciónNaciones UnidasConsejo de SeguridadBebés
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Ganadores y Perdedores del 11-S

2002

BushVidal-Beneyto JoséCensura11-SEstados UnidosAutocensuraCOMUNICACIÓNTerrorismoGuerraChomskyBin LadenPublicaciones: Obra periodística: Columnas y artículos de opiniónPolítica exteriorPerdedoresGanadoresAl QaedaValores americanosReligiónEstado de derechoPaz ciudadanaInformaciónAcción internacional
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Treatment of Advanced Hormone Receptor-Positive (HR+) HER2-negative Breast Cancer

2019

AbstractThe article gives an overview of current treatment options for metastatic hormone receptor-positive and HER2-negative breast cancer. The focus is on combined therapies, e.g., with CDK4/6 inhibition compared with purely endocrine-based therapies in the pre- and postmenopause, presenting the latest study results. The addition of a CDK4/6 inhibitor to endocrine-based therapy with an aromatase inhibitor or fulvestrant leads to a marked improvement in progression-free survival and is independently beneficial whether palbociclib, ribociclib or abemaciclib is involved. The particular clinical status of inhibition of cyclin-dependent kinases argues for its use in the first-line treatment of…

CDK4/6-InhibitorOncologymedicine.medical_specialtymedicine.drug_classMetastasierungPalbociclibCDK4/6 inhibitorHER2-negativMetastasisMammakarzinom03 medical and health scienceschemistry.chemical_compoundbreast cancer0302 clinical medicineBreast cancerInternal medicineMaternity and MidwiferyReview/ÜbersichtmetastasisEndocrine systemMedicineGebFra ScienceAbemaciclib030219 obstetrics & reproductive medicineAromatase inhibitorFulvestrantbusiness.industryhormonrezeptorpositivObstetrics and Gynecologymedicine.diseasechemistryHormone receptorhormone receptor-positivebusinessHER2-negativemedicine.drugGeburtshilfe und Frauenheilkunde
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The diffusion and influence of theoretical models of information behaviour : the case of Savolainen's ELIS model

2020

PurposeTo ascertain the diffusion and influence of Savolainen's ELIS model and its use as a theoretical and/or methodological basis for research.Design/methodology/approachA context citation analysis was made of the work where this researcher published his model. Analysis covered the year of publication, the type of work and the subject matter of the citing documents concerned. In-context citations were analysed for their frequency in each citing text, style, location and content cited.FindingsThe ELIS model received 18.5 cites/year. 20.2 per cent of them corresponded to papers published in journals in other areas, mainly computer science. The average of cites per paper was 1.8; 64.5 percen…

CITES05 social sciencesTheoretical modelsContext (language use)Ciències de la informacióLibrary and Information Sciences050905 science studiesPopularityStyle (sociolinguistics)InvestigacióCitation analysisInformació Teoria de la0509 other social sciencesSocial scienceParagraph050904 information & library sciencesSentenceInformation Systems
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WILLINGNESS TO RECEIVE COVID-l9 VACCINATION IN COSTUMERS ACCESSING COMMUNITY PHARMACIES IN THE PROVINCE OF PALERMO.ITALY.

2021

In Italy, vaccination against COVID-l 9 began on December 27, 2020. To date, 13,7 13,224 people in Italy are fully vaccinated, which accounts îor 25.3 oh of the general population, and 44.804 received at least one vaccination dose. Thc prescnt study aim to investigate willingness to receive COVID-I9 vaccination in costumers accessing a sample of community pharmacies in the Province of Palermo, Italy. A self- administered and anon),rnous questionnaire was carried out among costumers older than 18 ycars old between Dcccmbcr 2020 atrd March 2021. Three hundred and sixty-three subjects were enrolled in the study, 259 (71.3%) expressed their willingness to receive COVID-19 vaccination. The main …

COVID-19 vaccination willingness community pharmacies vaccine acceptance
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Analysis of Profiles of Family Educational Situations during COVID-19 Lockdown in the Valencian Community (Spain)

2022

Due to the pandemic (COVID-19), the education system in Spain was forced to close for three months, creating an unprecedented situation: improvised distance schooling. Family characteristics and their life situations with Information and Communication Technology use would be aspects to be studied as educational conditioning factors. This paper presents the ways in which a representative sample of families in the Valencian Community (Spain) assumed the education of their children during the lockdown. Mixed methods (quantitative -surveys-/qualitative -focus groups-) are used. Multivariate profiles are studied (k-means cluster) that summarise the life circumstances, represented by composite in…

COVID-19; school at home; inequality gaps; teaching methodology; family participation; ICTTecnologia de la informacióGeneral Social SciencesFamília i escolaVirusEnsenyament
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