Search results for "MACRO"

showing 10 items of 3471 documents

CO rebinding kinetics and molecular dynamics simulations highlight dynamic regulation of internal cavities in human cytoglobin

2013

Abstract: Cytoglobin (Cygb) was recently discovered in the human genome and localized in different tissues. It was suggested to play tissue-specific protective roles, spanning from scavenging of reactive oxygen species in neurons to supplying oxygen to enzymes in fibroblasts. To shed light on the functioning of such versatile machinery, we have studied the processes supporting transport of gaseous heme ligands in Cygb. Carbon monoxide rebinding shows a complex kinetic pattern with several distinct reaction intermediates, reflecting rebinding from temporary docking sites, second order recombination, and formation (and dissociation) of a bis-histidyl heme hexacoordinated reaction intermediate…

Genetics and Molecular Biology (all)ProteomicsProtein FoldingProtein ConformationMolecular biologylcsh:MedicineCrystallography X-RayLigandsBiophysics SimulationsBiochemistrychemistry.chemical_compoundProtein structureMacromolecular Structure AnalysisCinètica enzimàticaBinding Sites; Carbon Monoxide; Crystallography X-Ray; Globins; Humans; Kinetics; Ligands; Molecular Dynamics Simulation; Oxygenases; Point Mutation; Protein Binding; Protein Conformation; Medicine (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Biomacromolecule-Ligand Interactionslcsh:ScienceHemeCarbon MonoxideCrystallographyHemoproteinsMultidisciplinaryMedicine (all)PhysicsCytoglobinMetabolismeGlobinsBiochemistryOxygenasesddc:500Engineering sciences. TechnologyProtein BindingResearch ArticleBioquímicaProtein StructureBiophysicsReaction intermediateMolecular Dynamics SimulationProtein ChemistryGeneticsHumansPoint MutationGlobinProtein InteractionsBiologyBiologia molecularBinding SitesLigandCytoglobinlcsh:REnzyme kineticsOxygen transportProteinsComputational BiologyKineticsMetabolismAgricultural and Biological Sciences (all)chemistryX-RayBiophysicslcsh:QHuman medicineGenèticaCarbon monoxide
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Mitochondrial Dna Variation in Rhopalosiphum padi (Homoptera: Aphididae) Populations from four Spanish Localities

1992

In total, 35 clones of the bird cherry-oat aphid, Rhopalosiphum padi (L.) established from samples collected in four distant localities of Spain during fall 1989 and spring 1990 were examined for mitochondrial DNA variation using 20 restriction endonucleases. Individual parthenogenetic adults were used to establish clonal lines on wheat (‘Talento’) seedlings. Restriction site polymorphism was detected only with endonuclease Rsa I, but no statistical treatment of data could be done until more polymorphic endonucleases are found. Length variation of the mitochondrial DNA molecule, however, was extensive among R. padi clones. Distribution among populations of this size polymorphism was used to…

GeneticsAphidMitochondrial DNAbiologyBarley yellow dwarfRhopalosiphum padiInsect ScienceHomopterafood and beveragesMacrosiphum rosaeAphididaeRestriction fragment length polymorphismbiology.organism_classificationAnnals of the Entomological Society of America
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Tubulin gene expression persists during all changes in microtubular arrays related to cell shaping in growing barley leaves

1998

Summary Levels of α-tubulin RNA were determined in consecutive leaf segments taken along young, growing barley leaves by Northern blotting. The leaves exhibited a developmental gradient typical of graminaceous species ranging from a meristem at the base to fully differentiated cells at the tip. The objective was to ascertain whether or not high steady-state tubulin RNA levels accompany characteristic changes in microtubular arrays known to occur during cell division and differentiation. Of particular interest was the differentiation zone comprising a succession of well defined changes in microtubular arrays that appear to be involved in the control of cell shaping. High steady-state levels …

GeneticsbiologyCell divisionPhysiologyCellular differentiationRNAmacromolecular substancesPlant ScienceMeristemCell biologyTubulinMicrotubuleGene expressionbiology.proteinHordeum vulgareAgronomy and Crop ScienceJournal of Plant Physiology
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Deletion of myosin VI causes slow retinal optic neuropathy and age-related macular degeneration (AMD)-relevant retinal phenotype

2015

The unconventional myosin VI, a member of the actin-based motor protein family of myosins, is expressed in the retina. Its deletion was previously shown to reduce amplitudes of the a- and b-waves of the electroretinogram. Analyzing wild-type and myosin VI-deficient Snell’s Waltzer mice in more detail, the expression pattern of myosin VI in retinal pigment epithelium, outer limiting membrane, and outer plexiform layer could be linked with differential progressing ocular deficits. These encompassed reduced a-waves and b-waves and disturbed oscillatory potentials in the electroretinogram, photoreceptor cell death, retinal microglia infiltration, and formation of basal laminar deposits. A pheno…

Genotypegenetic structuresOuter retinaTranslocator protein TSPOOuter plexiform layermacromolecular substancesBiologyRetinaPhotoreceptor cellMouse modelStereociliaMacular DegenerationMiceCellular and Molecular Neurosciencechemistry.chemical_compoundOptic Nerve DiseasesMyosinmedicineAnimalsBipolar cellMolecular BiologyPharmacologyRetinaRetinal pigment epitheliumMyosin Heavy ChainsNeurodegenerationInner retinaChoriocapillarisRetinalCell BiologyAnatomyMacular degenerationmedicine.diseaseSynapseeye diseasesCell biologyMice Inbred C57BLmedicine.anatomical_structurechemistryMolecular MedicineMicrogliasense organsGene DeletionResearch ArticlePhotoreceptor Cells VertebrateCellular and Molecular Life Sciences
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Invasions of the non-indigenous red alga Lophocladia lallemandii (Montagne) F. Schmitz off the Island of Ischia (Tyrrhenian Sea, Italy)

2021

This paper describes the distribution and spread of the non-indigenous red alga Lophocladia lallemandii (Montagne) F. Schmitz along the coast of the Island of Ischia (Tyrrhenian Sea, Italy). Lophocladia lallemandii was monitored through surveys from July 2019 to January 2020 at the Capo Sant’Angelo (Ischia), where L. lallemandii was observed, but not reported, in the years preceding the invasion of the upper rocky infralittoral shore reported here. It is noteworthy that a large portion of the study area is included within one of the two “B no-take” zones of the Marine Protected Area of the “Regno di Nettuno” (“Neptune’s Realm”). During the surveys, the alga was first observed in the middle …

GeographyEcologyEcologySettore BIO/02 - Botanica SistematicaSettore BIO/03 - Botanica Ambientale E Applicatabiological invasions alien species macroalgae monitoring phenology associated fauna Mediterranean SeaEcology Evolution Behavior and SystematicsIndigenousLophocladiaBioInvasions Records
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Pollen and Plant Macroremain Analyses for the Reconstruction of Environmental Changes in the Early Metal Period

2006

A sharp increase in human population density and the same time fundamental changes in the location of settlement, moving away from earlier inhabited places points to significant changes in the environment. This period with a sharp decrease in anthropogenic indicators and poor records of slash and burn cultivation and field crop-growing is named “transition” period (Vasks et.al.1998) and indicates the lack of stable and continuous inhabitant sites. This phenomena can be explained by the small size of settlements at the Early Iron Age, expressed by a weak cultural layer and these could be defined as separate farmsteads. Modern farming practices, especially modern tillage, adversely affected t…

GeographyIron AgeHuman settlementPollenBotanymedicinePeriod (geology)MacrofossilSlash-and-burnPhysical geographymedicine.disease_causePopulation densityHolocene
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STOP 5: Veselava end moraine, north-western Vidzeme Upland

2014

GeographyKvartāra ģeoloģijaVidzemes augstieneDeglaciation:NATURAL SCIENCES::Earth sciences::Exogenous earth sciences::Sedimentology [Research Subject Categories]Physical geographyWeichselian glaciation:NATURAL SCIENCES::Earth sciences::Exogenous earth sciences::Quaternary geology [Research Subject Categories]deglaciationTerminal moraineWeichselian glaciationtill macrofabric
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Geographical patterns of species turnover in aquatic plant communities

2001

1. A classic theory in biogeography predicts that high latitude communities are unstable. This may be because of decreased species richness or decreased environmental predictability and productivity towards the poles. 2. We studied latitudinal patterns in long-term community persistence of aquatic vascular plants in 112 Finnish lakes, situated within a 1000-km range from the northernmost to the southernmost lake. 3. Contrary to theoretical predictions, we found that the turnover rate of plant species in 45 years was inversely related to latitude. That is, plant communities in northern lakes were more persistent than communities in southern lakes. When we used multiple regression to find the…

GeographyProductivity (ecology)TurnoverEcologyRange (biology)BiogeographyPlant communitySpecies richnessAquatic ScienceLatitudeMacrophyteFreshwater Biology
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Updated description and distribution of the Patagonian moss Ulota macrodontia Dusén ex Malta (Orthotrichaceae)

2021

Ulota macrodontia Dusen ex Malta is an Andean-Patagonian epiphytic moss that has been misunderstood in recent times (Garilleti et al. 2016). This may be due partly to the fact that it is a rarely c...

GeographybiologyMacrodontia (tooth)BotanymedicinePlant ScienceOrthotrichaceaeEpiphytebiology.organism_classificationmedicine.diseaseMossEcology Evolution Behavior and SystematicsJournal of Bryology
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Calls of the Jungle Crow (Corvus macrorhynchos s. l.) as a taxonomic characterResults of the Himalaya Expeditions of J. Martens, No. 224. - For No. 2…

2000

Summary A discriminant analysis of the call structure completely separates three Corvus taxa (levaillantii and japonensis of the ‘macrorhynchos group’, splendens) inhabiting the southern slopes of the Himalayas (Nepal, Kashmir). The acoustic differences are considered taxonomically relevant, indicating species boundaries. Therefore the Jungle Crows of lower and upper Nepal (contact zone at around 2,000 m) are assigned to two biospecies (C. japonensis and C. levaillantii), as is consistent with morphological, ecological and parasitological data. It appears possible to extrapolate the findings regarding call structure to the systematics of other ‘macrorhynchos’ populations as distant as the R…

GeographybiologyZoologyAnimal Science and Zoologybiology.organism_classificationJungle crowCorvus macrorhynchosJournal für Ornithologie
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