Search results for "MAI"

showing 10 items of 6279 documents

Azathioprine combined with prednisolone or monotherapy with prednisolone in active Crohn's disease

1993

Abstract Background: The role of azathioprine (AZA) in the treatment of active Crohn's disease (CD) is still controversial. This study examined whether AZA combined with standard prednisolone therapy improved the therapeutic outcome compared with monotherapy with prednisolone. Methods: Forty-two patients with a Crohn's Disease Activity Index (CDAI) of > 150 were randomized into two groups. Both received 60 mg of prednisolone daily in a tapering regimen to a maintenance dose of 10 mg. In addition, group 1 received 2.5 mg AZA/kg body wt and group 2 received a placebo over the whole study period of 4 months. Results: At the end of the trial, 16 of 21 patients (76%) in group 1 were in remission…

Adultmedicine.medical_specialtyAdolescentPrednisolonemedicine.medical_treatmentAzathioprinePlaceboGastroenterologylaw.inventionCrohn DiseaseRandomized controlled triallawInternal medicineAzathioprinemedicineHumansChemotherapyHepatologybiologyMaintenance dosebusiness.industryC-reactive proteinGastroenterologyMiddle AgedSurgeryRegimenTreatment OutcomePrednisolonebiology.proteinDrug Therapy Combinationbusinessmedicine.drugGastroenterology
researchProduct

Lens-vault analysis and its correlation with other biometric parameters using swept-source OCT

2021

Purpose To measure lens vault (LV) and to assess its correlation with various ocular parameters in healthy eyes, using for all measurements the same high-resolution swept-source optical coherence tomographer (SS-OCT). Methods We prospectively recruited 67 Caucasian healthy patients whose mean age was 41.9 ± 12.4 years; only their right eye was included in the study. Data were all recorded with the ANTERION SS-OCT and comprised, for each patient, 5 consecutive measurements of LV, anterior chamber depth (ACD), lens thickness (LT), axial length (AL), white-to-white (WTW) distance, central corneal thickness (CCT), anterior chamber volume (ACV) and spur-to-spur (STS) distance. Results Mean LV wa…

Adultmedicine.medical_specialtyBiometryAnterior ChamberSignificant negative correlationPositive correlationSwept-source Fourier domainCorrelationLens thicknessOphthalmologyLens CrystallineHumansMedicineOptical coherence tomographybusiness.industrySpur-to-spurReproducibility of ResultsMean ageAxial lengthWhite-to-whiteMiddle AgedClinical routineCrystalline lens riseAxial Length Eyemedicine.anatomical_structureLens (anatomy)Original ArticlebusinessTomography Optical CoherenceOptometryJournal of Optometry
researchProduct

Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura

2020

Abstract Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare but life-threatening condition. In 2018, the nanobody caplacizumab was approved for the treatment of adults experiencing an acute episode of aTTP, in conjunction with plasma exchange (PEX) and immunosuppression for a minimum of 30 days after stopping daily PEX. We performed a retrospective, observational analysis on the use of caplacizumab in 60 patients from 29 medical centers in Germany during acute disease management. Caplacizumab led to a rapid normalization of the platelet count (median, 3 days; mean 3.78 days). One patient died after late treatment initiation due to aTTP-associated complications. In 2 patients with…

Adultmedicine.medical_specialtyExacerbationmedicine.medical_treatmentThrombotic thrombocytopenic purpuraMedizin030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineFibrinolytic AgentsInternal medicinemedicineHumansRetrospective StudiesAcquired Thrombotic Thrombocytopenic PurpuraPurpura Thrombotic Thrombocytopenicbusiness.industryImmunosuppressionRetrospective cohort studyHematologySingle-Domain Antibodiesmedicine.diseasePurpuraDisease PresentationCardiovascular and Metabolic Diseases030220 oncology & carcinogenesisCaplacizumabmedicine.symptombusiness
researchProduct

Maintenance of weight loss after obesity treatment: is continuous support necessary?

2002

Abstract Objective: This study examined outcome differences of 109 obese subjects, who participated in a 10-week cognitive-behavioral inpatient treatment followed by either a weight maintenance program or a follow-up period without professional support. Methods: Self-rated weight loss, eating behaviors, and general psychopathology were assessed several months before treatment, when subjects were admitted, at discharge, and at the 6-, 12-, and 18-month follow-ups. Structured interviews for mental disorders and eating pathology were conducted additionally. Results: The mean weight of the sample at baseline was 127 kg. Weight loss of the total sample amounted to 8.0 kg (6.3%) and was completel…

Adultmedicine.medical_specialtyTime Factorsmedicine.medical_treatmentExperimental and Cognitive PsychologySeverity of Illness IndexBody Mass IndexWeight lossSurveys and QuestionnairesWeight maintenanceWeight LossmedicineHumansObesityPsychiatric Status Rating ScalesCognitive Behavioral TherapyMental DisordersProfessional supportmedicine.diseaseObesityPsychiatry and Mental healthClinical PsychologyGeneral psychopathologyStructured interviewPhysical therapyCognitive therapyFemaleObese subjectsmedicine.symptomEnergy IntakePsychologyFollow-Up StudiesBehaviour Research and Therapy
researchProduct

Psychometric properties of 12-item self-administered World Health Organization disability assessment schedule 2.0 (WHODAS 2.0) among general populati…

2019

WHODAS 2.0 is a unified scale to measuring disability across diseases, countries, and cultures. The objective was to explore the available evidence on the psychometric properties of 12-item self-administered WHODAS 2.0 among a general population and people with non-acute physical causes of disability.Five databases Medline, Embase, Web of Science, Scopus, and PsycINFO were searched for papers related to the validity, reliability, responsiveness, minimal clinically important difference or minimal detectable change of 12-item self-administered WHODAS 2.0. In order to avoid missing any potentially relevant studies, the search clauses were left as generic as possible and the refining search was…

Adultpsychometrics030506 rehabilitationPsychometricsPsychometricsdisability evaluationPopulationWHODASWorld Health OrganizationfunctioningDisability EvaluationYoung Adult03 medical and health sciences0302 clinical medicinevammaisuusInternational Classification of Functioning Disability and HealthFloor effectHumansDisabled Personstoimintarajoitteeteducationfloor effecteducation.field_of_studyconsistencyRehabilitationReproducibility of Resultsinternational classification of functioningpsykometriikkaSchedule (workplace)ceiling effectdisability and healthScale (social sciences)Self-AdministeredCeiling effectFemalereproducibility of results0305 other medical sciencePsychologyterveysarviointi030217 neurology & neurosurgeryClinical psychology
researchProduct

Impact of bioactive packaging systems based on EVOH films and essential oils in the control of aflatoxigenic fungi and aflatoxin production in maize.

2017

Aspergillus flavus and A. parasiticus are the most common fungal species associated with aflatoxin (AF) contamination of cereals, especially maize, and other agricultural commodities. AFB1, the most frequent and toxic metabolite, is a powerful hepatotoxic, teratogenic and mutagenic compound. Effective strategies to control these fungal species and AFs in food and feed are required. Active packaging film containing essential oils (EO) is one of the most innovative food packaging concepts. In this study, ethylene-vinyl alcohol (EVOH) copolymer films incorporating EO from Origanum vulgare (ORE), Cinnamomum zeylanicum (CIN) or their major active constituents, carvacrol (CAR) and cinnamaldehyde …

AflatoxinAntifungal AgentsCinnamomum zeylanicumActive packagingAspergillus flavusMicrobiologyAspergillus parasiticusZea maysCinnamaldehydechemistry.chemical_compound0404 agricultural biotechnologyAflatoxinsOriganumBotanyOils VolatileCarvacrolFood scienceAcroleinbiologyChemistryFood Packaging04 agricultural and veterinary sciencesGeneral MedicineOriganumbiology.organism_classificationBioactive ethylene-vinyl alcohol copolymer (EVOH)040401 food scienceAspergillus parasiticusMaizeFood packagingEssential oilsFood MicrobiologyMonoterpenesCymenesPolyvinylsFood ScienceAspergillus flavusInternational journal of food microbiology
researchProduct

Aspetti tipo-cronologici e archeometrici delle ceramiche africane nel territorio di Cignana (Naro, AG, Sicilia)

2020

Il progetto di ricerca, condotto in cotutela tra l'Università di Palermo e Aix-Marseille Université, si basa sullo studio delle ceramiche africane importate in Sicilia tra la fine del I e il VII secolo d.C.. La ricerca si basa sui frammenti - tutte le classi incluse - raccolti dal gruppo di ricerca di Palermo durante le ricognizioni archeologiche nei dintorni della villa romana di Cignana (Agrigento) e nell'entroterra di Termini Imerese (Palermo). L'approccio multidisciplinare archeologico ed archeometrico, condotto in collaborazione con diversi specialisti di queste discipline, ha permesso di definire l'origine delle diverse produzioni e di riflettere sulla loro circolazione in Sicilia, in…

Africa Sicily Agrigento Termini Imerese African potteries archaeological surveys archaeology archaeometry trades routes Roman EmpireSettore L-ANT/09 - Topografia AnticaAfrika Sizilien Agrigent Termini Imerese afrikanische Keramik archäologischer Survey Archäologie Archäometrie Handel Seewege römische KaiserzeitSettore L-ANT/07 - Archeologia ClassicaAfrique Sicile Agrigente Termini Imerese céramiques africaines prospections archéologiques archéologie archéométrie commerces routes Empire romain
researchProduct

Analyse des coûts de l'enseignement primaire télévisuel en Côte d'Ivoire

1980

International audience

AfriqueCote d'IvoireTechnologie de l'éducation[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationComputingMilieux_MISCELLANEOUSAnalyse de coûtEnseignement primaire
researchProduct

Financement de l'enseignement en Afrique francophone (1- financement et politique de l'éducation, 2- Modalité de financement de l'enseignement supéri…

1985

référence interne : 85023

AfriqueDéveloppement de l'éducation[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationFinancement de l'enseignementPolitique éducativeEnseignement secondairePrêt étudiantSystème scolaireEnseignement primaireTaux de scolarisation
researchProduct

Towards a Better Understanding of the Functioning of School Systems for Better Decision Making : The Case of Primary Schools in Togo

1991

International audience

AfriqueEfficacité de l'enseignementPrise de décisionTogo[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationAméliorationFonctionnement du système éducatifAnalyseComputingMilieux_MISCELLANEOUSEnseignement primaire
researchProduct