Search results for "MAI"
showing 10 items of 6279 documents
Extracellular Domains of the Bradykinin B2 Receptor Involved in Ligand Binding and Agonist Sensing Defined by Anti-peptide Antibodies
1996
Many of the physiological functions of bradykinin are mediated via the B2 receptor. Little is known about binding sites for bradykinin on the receptor. Therefore, antisera against peptides derived from the putative extracellular domains of the B2 receptor were raised. The antibodies strongly reacted with their corresponding antigens and cross-reacted both with the denatured and the native B2 receptor. Affinity-purified antibodies to the various extracellular domains were used to probe the contact sites between the receptor and its agonist, bradykinin or its antagonist HOE140. Antibodies to extracellular domain 3 (second loop) efficiently interfered, in a concentration-dependent manner, with…
Low-dose dopamine agonist administration blocks vascular endothelial growth factor (VEGF)-mediated vascular hyperpermeability without altering VEGF r…
2006
No specific treatment is available for ovarian hyperstimulation syndrome (OHSS), the most important complication in infertile women treated with gonadotropins. OHSS is caused by increased vascular permeability (VP) through ovarian hypersecretion of vascular endothelial growth factor (VEGF)activating VEGF receptor 2 (VEGFR-2). We previously demonstrated in an OHSS rodent model that increased VP was prevented by inactivating VEGFR-2 with a receptor antagonist(SU5416).However,duetoitstoxicity(thromboembolism) and disruption of VEGFR-2-dependent angiogenic processes critical for pregnancy, this kind of compound cannot be used clinically to prevent OHSS. Dopamine receptor 2 (Dp-r2) agonists, use…
Integration of personality constructs: The role of traits and motivation in the willingness to exert effort in academic and social life domains
2014
There has been growing interest in recent years in exploring different types of personality constructs and the nature of inter-relationships between personality variables in predicting outcomes in different life domains. The present study explores how personality traits and autonomous goal motivation predict the willingness to invest effort in academic and social life domains. Using a sample of 4133 upper secondary school students in Germany, multilevel regression analyses yielded three main results. First, both personality traits and motivation were substantially related to the willingness to exert effort. Second, the mediation effect compared to the direct effect was relatively small. Thi…
Shared midgut binding sites for Cry1A.105, Cry1Aa, Cry1Ab, Cry1Ac and Cry1Fa proteins from Bacillus thuringiensis in two important corn pests, Ostrin…
2013
First generation of insect-protected transgenic corn (Bt-corn) was based on the expression of Cry1Ab or Cry1Fa proteins. Currently, the trend is the combination of two or more genes expressing proteins that bind to different targets. In addition to broadening the spectrum of action, this strategy helps to delay the evolution of resistance in exposed insect populations. One of such examples is the combination of Cry1A.105 with Cry1Fa and Cry2Ab to control O. nubilalis and S. frugiperda. Cry1A.105 is a chimeric protein with domains I and II and the C-terminal half of the protein from Cry1Ac, and domain III almost identical to Cry1Fa. The aim of the present study was to determine whether the c…
Data from: Effects of undergrowth removal and edge proximity on ground beetles and vascular plants in urban boreal forests
2019
Urban forests are regularly managed for human safety and aesthetic reasons, but they are crucial habitat for many species. Removals of undergrowth occur commonly in these forests, yet the ecological consequences of these operations are poorly understood. We sampled ground beetles (Coleoptera, Carabidae) and vascular plants along 20-m edge gradients in Finnish urban forests, in five stands treated 0.5−2.5 years earlier with undergrowth removal and in five untreated stands. We hypothesized that undergrowth removal and edge proximity would benefit opportunistic and open-habitat species, whereas shady-habitat species would be affected negatively. (1) Regarding carabids, diversity and evenness i…
Le financement des études supérieures par l'emprunt
1973
Dzelzceļš kā ainavas pārmaiņu virzītājspēks: Suntažu – Ērgļu posms
2015
Bakalaura darba „Dzelzceļš kā ainavas pārmaiņu virzītājspēks: Suntažu – Ērgļu posms” galvenais mērķis ir izvērtēt dzelzceļu kā ainavas veidotāju un pārmaiņu virzītājspēku Suntažu – Ērgļu posmā no 1930. gada līdz mūsdienām. Darbā aprakstīti ainavas pārmaiņu virzītājspēki un pieejamība kā viens no galvenajiem ainavas pārmaiņu virzītājspēkiem. Tajā sniegts ieskats par dzelzceļu vēsturi Latvijā, aprakstīta Rīgas – Ērgļu dzelzceļa līnijas izveide un nozīme. Ar izveidoto karšu palīdzību veikta ainavas pārmaiņu analīze Suntažu – Ērgļu posmā. Tiek aplūkota arī mūsdienu ainava Suntažu – Ērgļu posmā.
Risk Assessment of Fuel Quantity Indicator Replacement in ATR72 Aircraft
2015
Aircraft maintenance activities are rife with opportunities for error. The concurrent in-flight failure of all of the engines of a non-scheduled airline flight and the following list of human lives highlight one of these opportunities. As commonly recognized among flight operators, each flight safety agency follows the criteria of the International Civil Aviation Organization Annex 16 in which all the evidences of the technical investigation pave the way for avoiding future flight accidents or incidents. On the other hand, when the Italian penal procedure code was applied for the Tuninter aircraft ATR 72 (identification code TS-LBB) crash at issue on 6 August 2005 near Palermo (Italy), the…
Explicit Kutta Condition for Unsteady Two-Dimensional High-Order Potential Boundary Element Method
1997
An explicit unsteady pressure Kutta condition is discribed that was directly and efficiently implemented in a time domain high-order potential panel method so as to ensure the pressure equality on the upper and lower surfaces at the trailing edge of the airfoil at each time step.