Search results for "MAI"
showing 10 items of 6279 documents
L'émergence du référentiel marchand dans la tarification des cliniques privées algériennes : privatisation du financement et changement de paradigme
2021
La convergence tarifaire participe à la privatisation progressive du système de santé algérien amorcée depuis la fin des années 80. Le passage d’une logique de gratuité à une logique marchande pour accéder aux soins représente un bouleversement pour les patients. Afin d’appréhender la formation des tarifs dans le secteur de l’hospitalisation privée, nous avons mixé une enquête qualitative par entretiens semi-directifs auprès de 16 fondateurs de cliniques privées et l’administration d’un questionnaire auprès de 40 médecins permanents de ces cliniques disposant d’une activité à plein temps. Nos résultats montrent que l’absence d’une grille officielle de tarification des prestations de soins a…
Waveguiding properties of a photonic crystal fiber with a solid core surrounded by four large air holes
2009
The polarization-dependent guiding properties of a hexagonal-lattice photonic crystal fiber with a solid-core surrounded by four large air holes are investigated. The appearance of a polarization dependent cutoff frequency, together with several parameters as the birefringence, the modal effective area, the group velocity dispersion and the polarization dependent loss are analyzed. A collection of fibers with different structural parameters were fabricated and characterized. An effective anti-guide structure from at least 450 nm to 1750 nm, a polarizing fiber with a polarization dependent loss of 16 dB/m at 1550 nm, and an endlessly singlemode polarization-maintaining fiber with group biref…
Visible Light Generation and its Influence on Supercontinuum in Chalcogenide As2S3 Microstructured Optical Fiber
2011
We demonstrate visible light generation in chalcogenide As2S3 microstructured optical fiber. The generated visible light causes irreversible damage to the fiber core because of the high absorption coefficient of chalcogenide glasses in the visible band. The SCs (supercontinua) are measured in both untapered and tapered As2S3 fibers, no wider SC is obtained in the tapered one. The SC growth is prevented by the visible light generation since the damage to the fiber core decreases the fiber transmission substantially. This effect can be avoided by designing the fiber to enable the pump source to work in single-mode operation.
A Multicenter Trial of Specific Local Nasal Immunotherapy
2000
Objective: To assess the efficacy and safety of specific local nasal immunotherapy (LNIT) in powder form in patients with allergic rhinitis, using subjective and objective parameters. Study Design: A double-blind randomized multicenter trial of 102 patients with allergic rhinitis who were treated with specific LNIT for 8 consecutive months. Methods: After identifying allergens with the skin prick test and sensitization threshold dose with the specific nasal provocation test, 102 patients were selected, of whom 55 were allergic to mites and 47 were allergic to Graminaceae or Parietaria pollen. The specific treatments were self-administered using an insufflator in two phases (phase 1: increas…
A marching-on in time meshless kernel based solver for full-wave electromagnetic simulation
2012
A meshless particle method based on an unconditionally stable time domain numerical scheme, oriented to electromagnetic transient simulations, is presented. The proposed scheme improves the smoothed particle electromagnetics method, already developed by the authors. The time stepping is approached by using the alternating directions implicit finite difference scheme, in a leapfrog way. The proposed formulation is used in order to efficiently overcome the stability relation constraint of explicit schemes. In fact, due to this constraint, large time steps cannot be used with small space steps and vice-versa. The same stability relation holds when the meshless formulation is applied together w…
Amatas upes hidroloģiskā režīma ilgtermiņa un sezonālās izmaiņas
2017
Darba mērķis ir izvērtēt Amatas upes hidroloģiskā režīma sezonālās un ilgtermiņa izmaiņas mainīga klimata apstākļos. Darbā raksturots Gaujas baseina upju hidroloģiskais režīms un to ietekmējošie faktori, aplūkoti hidroloģiskā režīma pētījumi Latvijā un Baltijā. Veikts Amatas upes baseina fizioģeogrāfiskais raksturojums. Analizēti rezultāti par Amatas upes hidroloģiskā režīma raksturojošo parametru (caurplūdums, temperatūra, ledus izveidošanās un uzlūšanas datumi, ledstāves ilgums) sezonālajām un ilgtermiņa izmaiņām un to savstarpējo korelāciju ar meteoroloģiskajiem parametriem (gaisa temperatūra un atmosfēras nokrišņi) laika periodā no 1921.-2015. gadam. Noteces režīms raksturots, analizējo…
STRUMENTI E METODI PER INTEGRARE GLI ASPETTI AMBIENTALI NELLA MANUTENZIONE DEL PATRIMONIO ARCHITETTONICO
2022
La corretta e costante applicazione della manutenzione può assumere un ruolo chiave per garantire la qualità del patrimonio costruito e il soddisfacimento delle più recenti classi di requisiti ambientali. A tal fine, è necessario che le strategie che guidano la programmazione delle attività di manutenzione siano modellate sulle caratteristiche del manufatto in esame. In Italia una larga parte degli edifici risulta edificata prima del 1946 e, molti di questi seppur non strettamente tutelati dalla legge, possono presentare rilevanti caratteri morfologici o costruttivi che vanno opportunamente conservati. La manutenzione, condotta in un’ottica sistemica e multiscalare, comprendendo interventi …
Irreversible Inhibition of Epidermal Growth Factor Receptor Activity by 3-Aminopropanamides
2012
Irreversible epidermal growth factor receptor (EGFR) inhibitors contain a reactive warhead which covalently interacts with a conserved cysteine residue in the kinase domain. The acrylamide fragment, a commonly employed warhead, effectively alkylates Cys797 of EGFR, but its reactivity can cause rapid metabolic deactivation or nonspecific reactions with off-targets. We describe here a new series of irreversible inhibitors containing a 3-aminopropanamide linked in position 6 to 4-anilinoquinazoline or 4-anilinoquinoline-3- carbonitrile driving portions. Some of these compounds proved to be as efficient as their acrylamide analogues in inhibiting EGFR-TK (TK = tyrosine kinase) autophosphorylati…
Dissection of the relative contribution of the Schizosaccharomyces pombe Ctr4 and Ctr5 proteins to the copper transport and cell surface delivery fun…
2011
The Ctr1 family of proteins mediates high-affinity copper (Cu) acquisition in eukaryotic organisms. In the fission yeastSchizosaccharomyces pombe, Cu uptake is carried out by a heteromeric complex formed by the Ctr4 and Ctr5 proteins. Unlike human andSaccharomyces cerevisiaeCtr1 proteins, Ctr4 and Ctr5 are unable to function independently in Cu acquisition. Instead, both proteins physically interact with each other to form a Ctr4–Ctr5 heteromeric complex, and are interdependent for secretion to the plasma membrane and Cu transport activity. In this study, we usedS. cerevisiaemutants that are defective in high-affinity Cu uptake to dissect the relative contribution of Ctr4 and Ctr5 to the Cu…
Identification of a specific type of PD from acoustic emission frequency spectra
2001
The paper presents an attempt to apply spectral analysis tools in processing acoustic emission (AE) pulses generated by partial discharge (FD). The experimental part of the paper describes spark gaps generating four types of PD and specifies parameters of measured acoustic signals and recalls the system used for measurement and analysis of the frequency spectra. Also, a spectral analysis procedure is presented, and frequency-domain descriptors characterizing AE pulses are defined. The results of the analysis are given both as time plots and amplitude and energy density spectra, related to values of the associated descriptors. The spectral analysis results cover AE pulses generated in system…