Search results for "MAMMALS"

showing 10 items of 301 documents

Water soluble organometallic small molecules as promising antibacterial agents: synthesis, physical-chemical properties and biological evaluation to …

2022

This work was supported by the Spanish Ministerio de Economia y Competitividad (PID2019-106832RB-100, and SAF2017-82261-P grant cofounded by the European Regional Development Fund) and the Generalitat de Catalunya (2017SGR1720). J. A. M. Xavier acknowledges DOC-FAM program under the Marie Sklodowska-Curie grant agreement N degrees 754397. A. B. Buades, M. Nuez and J. A. M. Xavier are enrolled in the PhD program of the UAB.

Bacterial diseasesMicroorganismes -- Resistència als medicamentsMicrobial Sensitivity TestsorganometalliyhdisteetGram-Positive BacteriaInorganic ChemistryAnti-Infective AgentsMedicaments antiinfecciososDrug resistance in microorganismsGram-Negative BacteriaAnimalsHumansCobaltabisdicarbollide anionMammalsantimikrobiset yhdisteetkemiallinen synteesiMalalties bacterianesBacteriaDrug discoverybioaktiiviset yhdisteetWaterBacterial InfectionsAnti-Bacterial AgentsCrystal structuresAnti-infective agentsSurfactant behaviourIodine
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Complementary methods assessing short and long-term prey of a marine top predator ‒ Application to the grey seal-fishery conflict in the Baltic Sea.

2019

The growing grey seal (Halichoerus grypus) population in the Baltic Sea has created conflicts with local fisheries, comparable to similar emerging problems worldwide. Adequate information on the foraging habits is a requirement for responsible management of the seal population. We investigated the applicability of available dietary assessment methods by comparing morphological analysis and DNA metabarcoding of gut contents (short-term diet; n = 129/125 seals, respectively), and tissue chemical markers i.e. fatty acid (FA) profiles of blubber and stable isotopes (SIs) of liver and muscle (mid- or long-term diet; n = 108 seals for the FA and SI markers). The methods provided complementary inf…

Baltic StatespredatorsMolecular biologyTroutSeals EarlessMarine and Aquatic SciencesPredationSocial Sciencespredator populationMolecular biology assays and analysis techniquesFATTY-ACID-COMPOSITIONDIET COMPOSITIONPsychologyForagingpetokannatMammalssaaliseläimetSealsEcologyAnimal BehaviorNucleic acid analysisDatabase and informatics methodsFatty AcidsQSequence analysisREukaryotaTrophic InteractionsCommunity EcologyOsteichthyesVertebrates1181 Ecology evolutionary biologyMedicinepreyHALICHOERUS-GRYPUSDNA analysisFOOD-WEBResearch Articlegrey sealBioinformaticsECOLOGICAL REGIME SHIFTSScienceFisheriesMarine BiologyPHOCA-HISPIDA-BOTNICAfisherypetoeläimetGeneticsAnimalsGenetikMarine MammalsDNA sequence analysisEcosystemRINGED SEALSEkologiBehaviorSTABLE-ISOTOPE ANALYSISDNA-analyysiBLUBBEREcology and Environmental SciencesOrganismsBiology and Life SciencesCARBON ISOTOPESResearch and analysis methodskalatalousMolecular biology techniquesFishAmniotesEarth Sciences1182 Biochemistry cell and molecular biologyhalli (hylkeet)ZoologyPLoS ONE
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The association between body mass, metabolic rates and survival of bank voles

2009

Summary 1Many studies have been performed in an attempt to explain physiological, ecological and evolutionary factors behind inter- and intraspecific variation in basal metabolic rate (BMR) and maximum aerobic metabolic rate (VO2max). However, very little is known about the association between the traits and fitness components in populations of free-living animals. 2We studied the association between body size and the metabolic rates of bank voles Myodes (= Clethrionomys) glareolus and their survival, measured by repeated trappings across 2 years in an isolated, island population. All measured traits (body mass, BM; head width, HW; VO2max and BMR) were significantly repeatable over short (m…

Basal rateEvolutionary physiologyeducation.field_of_studyevolutionary physiologyEcologyPopulationBiologyLogistic regressionoxygen consumptionsurvivalIntraspecific competitionAnimal sciencefitnessBasal metabolic rateGenetic variationmammalsStabilizing selectioneducationEcology Evolution Behavior and SystematicsFunctional Ecology
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Considerations on an integrated biochronological scale of Italian Quaternary Mammals

2011

Viene analizzato il lavoro di MASINI e SALA (2007) sull’approccio integrato della distribuzione dei grandi e piccoli mammiferi dell’Italia continentale del tardo Pliocene e del Pleistocene, tenendo conto della nuova definizione del Quaternario, mettendo in risalto i punti di forza e quelli deboli della scala proposta. Vengono inoltre aggiunti nuovi dati sulla biocronologia a mammiferi del Pleistocene Superiore. The paper of MASINI and SALA (2007) regarding an integrated approach on the stratigraphic distribution patterns of large and small mammals in the late Pliocene and Pleistocene of the Italian peninsula is analysed, showing the weak and strong points. New data are presented on the mamm…

Biochronology Mammals Quaternary Italian peninsulaBiocronologia Mammiferi Quaternario Italia continentaleSettore GEO/01 - Paleontologia E Paleoecologia
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Mammal assemblage composition predicts global patterns in emerging infectious disease risk

2021

Abstract As a source of emerging infectious diseases, wildlife assemblages (and related spatial patterns) must be quantitatively assessed to help identify high‐risk locations. Previous assessments have largely focussed on the distributions of individual species; however, transmission dynamics are expected to depend on assemblage composition. Moreover, disease–diversity relationships have mainly been studied in the context of species loss, but assemblage composition and disease risk (e.g. infection prevalence in wildlife assemblages) can change without extinction. Based on the predicted distributions and abundances of 4466 mammal species, we estimated global patterns of disease risk through …

BiodiversityDIVERSITYAnimal Sciences DeskzoonoositCommunicable Diseases EmergingeläinmaantiedetartuntatauditBureau DierwetenschappenPrimary Research ArticleGeneral Environmental ScienceBODY-SIZEMammals2. Zero hungerGlobal and Planetary ChangeEcologyEcologyassemblage composition; climate change; emerging infectious diseases; habitat loss; infectious disease hotspots; species distributionsassemblage compositionPOPULATION-DENSITYeliöyhteisötriskinarviointiPE&RCEXTINCTION RISKclimate changespecies distributions1181 Ecology evolutionary biologyEmerging infectious diseaseWILDLIFEhabitat lossWildlifeContext (language use)Biologyemerging infectious diseasesEVENNESSnisäkkäätAnimalsEnvironmental ChemistryeläimistöEcosystemPATHOGENSSPECIES DISTRIBUTION MODELS15. Life on landilmastonmuutoksetPrimary Research ArticlesbiodiversiteettiHabitat destruction13. Climate actionInfectious disease (medical specialty)villieläimetWildlife Ecology and ConservationSpatial ecologyBIODIVERSITYSpecies richnessLIVING FASTEnvironmental Sciencesinfectious disease hotspots
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Synthetic biomolecular condensates to engineer eukaryotic cells

2021

Abstract The compartmentalization of specific functions into specialized organelles is a key feature of eukaryotic life. In particular, dynamic biomolecular condensates that are not membrane enclosed offer exciting opportunities for synthetic biology. In recent years, multiple approaches to generate and control condensates have been reported. Notably, multiple orthogonally translating organelles were designed that enable precise protein engineering inside living cells. Despite being built from only very few components, orthogonal translation can be engineered with subresolution precision at different places inside the same cell to create mammalian cells with multiple expanded genetic codes.…

Biomolecular CondensatesMammalsOrganellesComputer scienceProteinsProtein engineeringComputational biologyBiochemistryAnalytical ChemistrySynthetic biologyEukaryotic CellsGenetic CodeOrganelleAnimalsCurrent Opinion in Chemical Biology
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Production and characterisation of recombinant forms of human pulmonary surfactant protein C (SP-C):Structure and surface activity

2006

  Udgivelsesdato: 2006-Apr Surfactant protein C (SP-C) is an essential component for the surface tension-lowering activity of the pulmonary surfactant system. It contains a valine-rich alpha helix that spans the lipid bilayer, and is one of the most hydrophobic proteins known so far. SP-C is also an essential component of various surfactant preparations of animal origin currently used to treat neonatal respiratory distress syndrome (NRDS) in preterm infants. The limited supply of this material and the risk of transmission of infectious agents and immunological reactions have prompted the development of synthetic SP-C-derived peptides or recombinant humanized SP-C for inclusion in new prepar…

BioquímicaRecombinant membrain proteinSurface PropertiesSize-exclusion chromatographyMolecular Sequence DataPhospholipidBiophysicsBiologyBiochemistrylaw.inventionchemistry.chemical_compoundAffinity chromatographyPulmonary surfactantMembranes (Biologia)lawAnimalsHumansPulmonary surfactant-associated protein CAmino Acid SequenceLipid bilayerConserved SequencePhospholipidsMammalsDrug CarriersChromatographySequence Homology Amino AcidSP-CProteïnes de membranaSurfactant protein CPulmonary surfactantCell BiologyPulmonary Surfactant-Associated Protein CRecombinant ProteinsKineticschemistryBiochemistryRecombinant DNALipid-protein interactionPeptidesSequence Alignment
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Assessing autophagy in archived tissue or how to capture autophagic flux from a tissue snapshot

2020

This article belongs to the Special Issue Autophagy in Cancer.

Bioquímicaautophagy:Ciências da Saúde [Ciências Médicas]Ciências Médicas::Ciências da SaúdeCellular homeostasisAutofagia610 Medicine & healthBiologyGeneral Biochemistry Genetics and Molecular Biology:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]03 medical and health sciences0302 clinical medicineHuman disease:Chemicals and Drugs::Biological Factors::Biological Markers [Medical Subject Headings]:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Autophagy [Medical Subject Headings]lcsh:QH301-705.5030304 developmental biology0303 health sciencesdiseaseBiología molecularScience & TechnologyGeneral Immunology and MicrobiologyMechanism (biology)CommunicationAutophagyautophagy; biomarkers; pathology; diseasebiomarkersPatología3. Good healthCell biology:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Research Design::Reproducibility of Results [Medical Subject Headings]BiomarcadoresTejidoslcsh:Biology (General)030220 oncology & carcinogenesis570 Life sciences; biologypathologyGeneral Agricultural and Biological SciencesFlux (metabolism)Enfermedad:Phenomena and Processes::Physiological Phenomena::Physiological Processes::Homeostasis [Medical Subject Headings]
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Development and characterization of an experimental model of diet-induced metabolic syndrome in rabbit

2017

Metabolic syndrome (MetS) has become one of the main concerns for public health because of its link to cardiovascular disease. Murine models have been used to study the effect of MetS on the cardiovascular system, but they have limitations for studying cardiac electrophysiology. In contrast, the rabbit cardiac electrophysiology is similar to human, but a detailed characterization of the different components of MetS in this animal is still needed. Our objective was to develop and characterize a diet-induced experimental model of MetS that allows the study of cardiovascular remodeling and arrhythmogenesis. Male NZW rabbits were assigned to control (n = 15) or MetS group (n = 16), fed during 2…

Blood GlucoseMale0301 basic medicinePhysiologylcsh:MedicineBlood Pressure030204 cardiovascular system & hematologyVascular MedicineBiochemistryEatingchemistry.chemical_compound0302 clinical medicineGlucose MetabolismDietary SucroseBlood plasmaMedicine and Health Scienceslcsh:ScienceMammalsMetabolic SyndromeMultidisciplinaryLiver DiseasesFatty liverAnimal ModelsBody FluidsBloodExperimental Organism SystemsPhysiological ParametersLiverVertebratesHypertensionMetabolomeCarbohydrate MetabolismRabbitsAnatomyResearch Articlemedicine.medical_specialtyMean arterial pressureBilirubinDiastoleGastroenterology and HepatologyBiologyResearch and Analysis MethodsDiet High-FatBlood Plasma03 medical and health sciencesInternal medicineGlucose IntolerancemedicineAnimalsMetabolomicsObesityNuclear Magnetic Resonance BiomolecularNutritionAnalysis of VarianceBody Weightlcsh:ROrganismsBiology and Life Sciencesmedicine.diseaseDietFatty LiverDisease Models AnimalMetabolism030104 developmental biologyEndocrinologyBlood pressurechemistryAmnioteslcsh:QMetabolic syndromeSteatosisPLOS ONE
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HUMAN CHROMOSOME 4 SYNTENIC ASSOCIATIONS IN PLACENTAL MAMMALS

2009

CHROMOSOME EVOLUTION HSA4 PLACENTAL MAMMALSSettore BIO/08 - Antropologia
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