Search results for "MARS"

Interactive effects between physical forces and ecoystem engieneers on seed burial: a case study using Spartina anglica

2015

Seed burial (i.e. vertical seed dispersal) has become increasingly valued for its relevance for seed fate and plant recruitment. While ecosystem engineers have been generally considered as the most important drivers of seed burial, the role of physical forces, such as wind or water flow, has been largely overlooked. Using tidal habitats as a model system, and a combination of flume and mesocosm experiments, we investigated the effects of 1) currents, 2) benthic animals with different engineering activities and 3) their interplay on seed burial of a common salt marsh pioneer plant, Spartina anglica. Our results reveal that in such systems, water flow can be of equal or higher importance than…

Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes.

2016

Abstract Ethnopharmacological relevance Multidrug resistance (MDR) of cancer is often associated with the overexpression of ATP-binding cassette (ABC) transporters, such as P-glycoprotein (P-gp), multidrug resistance-associated protein-1 (MRP-1) and breast cancer resistance protein (BCRP or ABCG2), in cancer cells, which facilitates the active efflux of a wide variety of chemotherapeutic drugs out of the cells. Marsdenia tenacissima is a traditional Chinese medicinal herb that has long been clinically used for treatment of cancers, particularly in combinational use with anticancer drugs. Polyoxypregnanes (POPs) are identified as main constituents of this herb, and three of them have been re…

Ubiquitous giants: a plethora of giant viruses found in Brazil and Antarctica

2018

Background Since the discovery of giant viruses infecting amoebae in 2003, many dogmas of virology have been revised and the search for these viruses has been intensified. Over the last few years, several new groups of these viruses have been discovered in various types of samples and environments.In this work, we describe the isolation of 68 giant viruses of amoeba obtained from environmental samples from Brazil and Antarctica. Methods Isolated viruses were identified by hemacolor staining, PCR assays and electron microscopy (scanning and/or transmission). Results A total of 64 viruses belonging to the Mimiviridae family were isolated (26 from lineage A, 13 from lineage B, 2 from lineage C…

L’académie de Marseille dans la France des Lumières : les ambiguïtés du discours et d’une position

2016

International audience; ...

3D numerical modeling of an anthropogenic sinkhole in the Marsala area of western Sicily

2013

Situación de las poblaciones valencianas del género Marsilea: medidas para su conservación

2001

elena.estrelles@uv.es ana.ibars@uv.es Juan.J.Herrero@uv.es Se analiza la situación de las poblaciones valencianas de Marsilea batardae, M. quadrifolia y M. strigosa, así como las amenazas que actualmente pesan sobre ellas. Asimismo se comentan las medidas que se han puesto en marcha para asegurar su conservación, entre las que destacan las introducciones experimentales. The situation of Valencian populations of Marsilea batardae, M. quadrifolia and M. strigosa, as well as the threats that they suffer at present are analysed here. Likewise the measures applied to ensure their conservation, with emphasis on the experimental introductions, are commented.

Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo

2021

Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly due to the inhibitor specificity, toxicity, and drug interactions. Here, we reported that three polyoxypregnanes (POPs) as the most abundant constituents of Marsdenia tenacissima (M. tenacissima) were novel ABCB1-modulatory pro-drugs, which underwent intestinal microbiota-mediated biotransformation in vivo to generate active metabolites. The metabolites at non-toxic concentrations restored chemosensitivity in ABCB1-overexpressing cancer cells v…

Marsupialization facilitates movement of the cystic lesion-associated deeply impacted mandibular third molar in spite of its mature roots

2017

Background: The odontogenic cystic lesions happened in the angle and ramus region are frequently associated with impacted mandibular third molars. The treatment plan was difficult to work out for the huge cystic lesions with deeply impacted third molars, since the enucleation with simultaneously removing the deeply impacted teeth may cause serious complications. Therefore, the marsupialization of the cystic lesions followed by enucleation with tooth removal has also been advocated. The aim of this study was to explore the movement of cystic lesion-associated deeply impacted mandibular third molars (IMTM) after marsupialization. Material and Methods: Between July 2009 and December 2015, pati…

Deteriorating Weather Conditions Predict the use of Suboptimal Stopover Sites by Aquatic WarblersAcrocephalus paludicola

2011

Abstract. The Aquatic Warbler Acrocephalus paludicola is a globally threatened songbird and its decline is related to habitat loss. Accordingly, most studies dealing with the stopover ecology of this species have been chiefly focused on the habitat use and the availability of suitable habitats along its route of migration. In contrast, much less attention has been paid to other environmental causes potentially explaining the use of stopover sites. Our aim here was to investigate whether the Aquatic Warbler at an apparently suboptimal stopover site with small area of suitable habitats stops over only during adverse weather conditions. We used data obtained at a suboptimal (Jaizubia marshland…

Willem Boshoff, artist's monograph and catalogue

2013

Willem Boshoff’s work articulates around a pivotal date, April 1994, the first democratic elections in South Africa. He may choose to work gigantic rocks of granite or establish vast installations of accumulated material. The artist claims that his work is based on language, often taking the form of Dictionaries. While reviewing the main questions by artists of the twentieth century, texts or artworks from Europe are systematically tested against their South African counterpart. Boshoff’s attitude is determined by a melancholic questioning of his role as a creator linked to a political situation and cultural milieu. He discovers more dynamic ways of presenting gestures when his artistic act…