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showing 10 items of 16762 documents

Pressure-Stabilized Solvates of Xylazine Hydrochloride

2016

High pressure strongly favors the highest-density polymorph Z of active pharmaceutical ingredient 2-(2,6-xylidino)-5,6-dihydro-4H-1,3-thiazine hydrochloride (xylazine hydrochloride, XylHCl) up to about 0.1 GPa only, but still higher pressure destabilizes this structure. Above 0.1 GPa, XylHCl preferentially crystallizes as solvates with CH2Cl2, CHCl3, or (CH3)2CHOH depending on the solvent used. However, when XylHCl·H2O is dissolved in any of these solvents, the high-pressure crystallizations yield the hydrate XylHCl·H2O only. The single crystals of the CH2Cl2, CHCl3, and (CH3)2CHOH solvates could be grown in situ in a diamond anvil cell, which allowed their structure determination from the …

Active ingredientPhase transitionChemistryHydrochloride02 engineering and technologyGeneral Chemistry010402 general chemistry021001 nanoscience & nanotechnologyCondensed Matter Physics01 natural sciencesXylazine Hydrochloride0104 chemical sciencesSolventCrystallographychemistry.chemical_compoundHigh pressureYield (chemistry)General Materials Science0210 nano-technologyHydrateCrystal Growth & Design
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Solubility and acid-base properties and activity coefficients of chitosan in different ionic media and at different ionic strengths, at T=25°C

2009

Studies on the acid-base properties and solubility of a polyammonium polyelectrolyte (chitosan) with different molecular weights (MW 310 and 50 kDa), were performed at T=25 °C, in the pH range 2.5–7. The protonation of chitosan was investigated by potentiometry ([H+]-glass electrode) in NaCl, NaNO3 and mixed NaNO3+Na2SO4 ionic media, at different ionic strengths. Protonation constants were calculated as a function of dissociation degree α by means of two different models, namely, a simple linear model and the modified Henderson–Hasselbalch equation. Experimental data were also fitted using a model independent of α (Diprotic-like model), according to which the acid-base properties can be sim…

Activity coefficientChemistryInorganic chemistryIonic bondingProtonationChitosan Acid-base properties Solubility Activity coefficients Ion pair formationCondensed Matter PhysicsSettore CHIM/12 - Chimica Dell'Ambiente E Dei Beni CulturaliAtomic and Molecular Physics and OpticsDissociation (chemistry)Electronic Optical and Magnetic MaterialsSpecific ion interaction theoryIonic strengthStability constants of complexesMaterials ChemistrySettore CHIM/01 - Chimica AnaliticaPhysical and Theoretical ChemistrySolubilitySpectroscopyJournal of Molecular Liquids
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A fluorescence spectroscopy study of the interaction of monocationic quinine with phospholipid vesicles Effect of the ionic strength and lipid compos…

1997

Abstract The interaction of monocationic quinine with zwitterionic dimyristoyl phosphatidylcholine (DMPC) and mixed negatively-charged dimyristoylphosphatidyl glycerol (DMPG) DMPC small unilamellar vesicles in the liquid-crystalline phase was investigated by steady-state fluorescence spectroscopy at pH 7 and 37°C. The maximum fluorescence emission peak at 383 nm, upon excitation at 335 nm, shifts to lower wavelength and decreases its intensity as the ratio between the total lipid and quinine concentrations increases. This indicates that in the membrane-bound state quinine is in an environment of low polarity, more deeply buried when anionic DMPG is present in the vesicle. For monoprotonated…

Activity coefficientChemistryVesicleLipid BilayersOsmolar Concentrationtechnology industry and agricultureAnalytical chemistryPhosphatidylglycerolsFluorescenceAtomic and Molecular Physics and OpticsFluorescence spectroscopyAnalytical Chemistrychemistry.chemical_compoundSpectrometry FluorescenceMembraneIonic strengthPhase (matter)PhosphatidylcholineBenzoquinoneslipids (amino acids peptides and proteins)DimyristoylphosphatidylcholineInstrumentationPhospholipidsSpectroscopySpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
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Modelling of the ternary system H3PO4/H2O/TBP

2002

Abstract A thermodynamic model is presented for the extraction of phosphoric acid from water by tri-n-butylphosphate (TBP), from aqueous solutions containing 0–6 mol/kg phosphoric acid. The activity coefficient of phosphoric acid was calculated from experimental data using Pitzer’s equation, and those of the components in the organic phase were calculated by Sergievskii–Danus’s relationship. The proposed model gives a satisfactory description of the distribution of phosphoric acid and water, in the considered concentration range, by taking into account the formation of the following species: TBP, TBP·H2O, H3PO4·TBP and (TBP)2·H3PO4·H2O.

Activity coefficientChromatographyAqueous solutionTernary numeral systemChemistryGeneral Chemical EngineeringInorganic chemistryExtraction (chemistry)General Physics and AstronomyThermodynamic modelchemistry.chemical_compoundPhase (matter)Physical and Theoretical ChemistryPhosphoric acidFluid Phase Equilibria
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Co-adsorption of 1,2-dichloroethane and 1-bromo,2-chloroethane on zeolite ZSM-5 from the liquid and vapour phases, using the Myers-Prausnitz-Dubinin …

2002

Abstract The adsorption/co-adsorption of 1,2-dichloroethane (DCA) and 1-bromo,2-chloroethane (BCA) from the vapour and the liquid phases by zeolite ZSM-5 at ambient temperature is reported, using Dubinin's theory and the recent Myers-Prausnitz-Dubinin (MPD) theory. For adsorption from the liquid phase, the activity coefficients in the adsorbed and the liquid states are the same and no selectivity is observed. This is confirmed by the absence of an excess enthalpy of immersion of ZSM-5 into the mixtures. Adsorption from the vapour phase proceeds in two stages, as indicated by double Dubinin-Astakhov (DA) plots. If one considers only the domain of high relative pressure, co-adsorption is desc…

Activity coefficientEnthalpyThermodynamicsGeneral Chemistry12-DichloroethaneCondensed Matter PhysicsMolecular sievechemistry.chemical_compoundAdsorptionchemistryMechanics of MaterialsPhase (matter)Organic chemistryGeneral Materials ScienceZSM-5ZeoliteMicroporous and Mesoporous Materials
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Calculations of organic-solvent dispersions of single-wall carbon nanotubes

2005

The aqueous solubility Sw and 1-octanol–(Po), cyclohexane–(Pch), and chloroform–(Pcf) water partition coefficients are calculated. The properties of single-wall carbon nanotubes (SWNT) are related to the indices (n, m) designating the chiral vector. SWNTs are classified in zigzag (n, 0), armchair (n, n), and chiral (n, m). These properties permit classifying SWNTs according to (n, m). Correlations between (n2 + nm + m2)1/2, log Sw, log Po, log Pch, and log Pcf show that (n, m) are adequate indices. The (10,10) is the most abundant SWNT, presenting consistency between great kinetic stability, small Sw, and great {Po, Pch, Pcf}. The room temperature solubility of SWNTs is investigated in a va…

Activity coefficientPermittivityChemistryAnalytical chemistryCarbon nanotubeCondensed Matter PhysicsKinetic energyAtomic and Molecular Physics and Opticslaw.inventionPartition coefficientlawElectron affinityOrganic chemistryLewis acids and basesPhysical and Theoretical ChemistrySolubilityInternational Journal of Quantum Chemistry
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Phase equilibria in the systems isobutyl alcohol+N,N-dimethylformamide, isobutyl acetate+N,N-dimethylformamide and isobutyl alcohol+isobutyl acetate+…

2005

Abstract Consistent vapor–liquid equilibria (VLE) were determined for the ternary system isobutyl alcohol (IBA) + isobutyl acetate (IBAc) + N,N-dimethylformamide (DMF) and two constituent binary systems at 101.3 kPa. The IBA + DMF system exhibits negative deviation from ideal behaviour and IBAc + DMF system deviates positively from ideal behaviour. The activity coefficients of the solutions were correlated with its composition by the Wilson, NRTL and UNIQUAC models. The ternary system is well predicted from binary interaction parameters.

Activity coefficientTernary numeral systemUNIQUACIsobutyl acetateGeneral Chemical EngineeringGeneral Physics and AstronomyAlcoholIsobutyl alcoholMedicinal chemistrychemistry.chemical_compoundchemistryPhase (matter)Non-random two-liquid modelOrganic chemistryPhysical and Theoretical ChemistryFluid Phase Equilibria
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Isobaric vapor-liquid equilibria and densities for the system methyl 1,1-dimethylethyl ether+2-propanol

2002

Vapor-liquid equilibrium data at 50, 75 and 94 kPa have been determined for the binary system methyl 1,1-dimethylethyl ether + 2-propanol, in the temperature range 308-344 K. The measurements were made in an equilibrium still with circulation of both the vapor and liquid phases. Excess volumes have been also determined from density measurements using a vibrating tube densimeter at 298.15 K. The system exhibits positive deviation from ideal behavior and does not present azeotropy within the range of pressures studied. The excess volume of the system is negative over the whole mole fraction range. The activity coefficients and boiling points of the solutions were well correlated with the mole…

Activity coefficientUNIQUACChemistryThermodynamicsCondensed Matter PhysicsMole fractionElectronic Optical and Magnetic MaterialsPropanolBoiling pointchemistry.chemical_compoundMolar volumeMaterials ChemistryNon-random two-liquid modelVapor–liquid equilibriumPhysical and Theoretical Chemistry
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Phase equilibria involved in extractive distillation of dipropyl ether+1-propyl alcohol using 2-ethoxyethanol as entrainer

2007

Abstract Consistent vapour–liquid equilibrium data at 101.3 kPa have been determined for the ternary system dipropyl ether + 1-propyl alcohol + 2-ethoxyethanol and two constituent binary systems: dipropyl ether + 2-ethoxyethanol and 1-propyl alcohol + 2-ethoxyethanol. The dipropyl ether + 2-ethoxyethanol system shows positive deviations from ideal behaviour and 1-propyl alcohol + 2-ethoxyethanol system exhibits no deviation from ideal behaviour. The activity coefficients and the boiling points were correlated with their compositions by the Wilson, NRTL and UNIQUAC equations. It is shown that the models allow a very good prediction of the phase equilibria of the ternary system using the pert…

Activity coefficientUNIQUACTernary numeral systemGeneral Chemical EngineeringGeneral Physics and AstronomyThermodynamics2-Ethoxyethanolchemistry.chemical_compoundchemistryPhase (matter)Non-random two-liquid modelOrganic chemistryExtractive distillationBinary systemPhysical and Theoretical ChemistryFluid Phase Equilibria
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Thermodynamic properties and conductivities of some dodecylsurfactants in water

1988

Densities, heat capacities, enthalpies of dilution, osmotic coefficients and conductivities are reported for dodecylamine hydrochloride, dodecyldimethylammonium and dodecyltrimethylammonium chloride in water over a wide range of concentration. The last two properties were also measured for dodecyltrimethylammonium bromide. From the thermodynamic data partial molar volumes, heat capacities and relative enthalpies and nonideal free energies and entropies were derived as a function of the surfactant concentration. The cmc's and degree of counterion dissociation were also calculated from the transport properties. It is shown that the trends of volumes, enthalpies, free energies and entropies ar…

Activity coefficientchemistry.chemical_classificationQuantitative Biology::BiomoleculesAqueous solutionInorganic chemistryThermodynamics of micellizationBiophysicsThermodynamicsBiochemistryMicelleDissociation (chemistry)DilutionCondensed Matter::Soft Condensed MatterchemistryPulmonary surfactantPhysics::Chemical PhysicsPhysical and Theoretical ChemistryCounterionMolecular BiologyJournal of Solution Chemistry
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