Search results for "MAZ"
showing 10 items of 3205 documents
Effects of several degrees of chronic social defeat stress on emotional and spatial memory in CD1 mice
2015
In the present study, the effects of several degrees of CSDS (Chronic Social Defeat Stress) on emotional and spatial memory in mice were evaluated in separate experiments. Male CD1 mice were randomly assigned to four experimental groups (n=10-12) for each experiment: NS (non-stressed), S5, S10 and S20 (5, 10 and 20 sessions of CSDS, respectively). The S groups underwent the corresponding number of agonistic encounters (10min each) over a 20-day period. 24h after the last session of CSDS, mice performed the inhibitory avoidance (Experiment 1) or the Morris water maze test (Experiment 2). In both experiments, animals were also evaluated in the elevated plus maze for 5min to obtain complementa…
Inhibitory avoidance learning in CD1 mice: Effects of chronic social defeat stress
2015
Chronic social defeat stress (CSDS) is an animal model widely used to determine the neurobiological mechanisms of stress and its associated pathologies. In this study, the effects of CSDS on inhibitory avoidance (IA) were evaluated in post-pubertal and adult male CD1 mice, instead of the C57BL/6J strain used in the CSDS standard protocol. CSDS consisted of daily 5-min (experiments 1 and 2) or 10-min (experiment 3) agonistic encounters on 21 consecutive days. Twenty four hours after the last session of CSDS, all the mice were tested for IA. They were also evaluated in an elevated plus-maze, obtaining complementary measures of locomotor activity and emotionality. In experiments 1 and 2, IA le…
Enhanced habit-based learning and decreased neurogenesis in the adult hippocampus in a murine model of chronic social stress
2009
Abstract Stress can induce preferential engagement of habit learning mediated by the basal ganglia, relative to learning that involves complex spatial associations contributed by the hippocampal formation. We explored in mice the influence that chronic episodes of social stress exert on the selection of cognitive/spatial vs. habit-based learning strategies. Male mice were exposed to repeated episodes of social confrontation and were categorized as dominant, subordinate or undetermined according to quantitative ethologically relevant parameters of aggression. Mice were then trained in a conditional discrimination task in the T-maze in the presence of allocentric cues until five correct choic…
L’incontro tra normativa, dottrina e prassi nelle seicentesche Decisiones penali dei supremi tribunali del Regnum Siciliae
2016
In questo articolo si analizza l'incontro tra normativa, dottrina e prassi giurisprudenziale nelle opere della dottrina penalistica siciliana della prima età moderna, e la rilevanza di tale incontro nella formazione del diritto vigente di quel periodo
Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and…
2009
Neurogenesis in the adult dentate gyrus (DG) of the hippocampus has been implicated in neural plasticity and cognition but the specific functions contributed by adult-born neurons remain controversial. Here, we have explored the relationship between adult hippocampal neurogenesis and memory function using tasks which specifically require the participation of the DG. In two separate experiments several groups of rats were exposed to fractionated ionizing radiation (two sessions of 7 Gy each on consecutive days) applied either to the whole brain or focally, aiming at a region overlying the hippocampus. The immunocytochemical assays showed that the radiation significantly reduced the expressio…
I doveri di informazione
2007
Il saggio,alla data della sua pubblicazioe, si offriva quale primo tentativo di ricstruzione in chiave sistematica delle diverse scelte della normativa di fonte comunitaria in materia di doveri di informazione nei contratti dei consumatori. L'indagine, condotta in aderenza alla ratio della normativa, consente di cogliere ,insieme, la funzione di volta in volta affidata all'informazione e,dunque, la sua collocazione nella vicenda contrattuale e gli effetti nella medesima vicenda della violazione di tali doveri ( che la normativa in vigore sembrava prima facie limitare al prolungamet dei termini per l'esercizio del recesso). Il guadagno ricostruttivo è di tutto rilievo, specie nei casi in cui…
Subsurface flow and large-scale lateral saturated soil hydraulic conductivity in a Mediterranean hillslope with contrasting land uses
2017
Abstract The lateral saturated hydraulic conductivity, Ks,l , is the soil property that mostly governs subsurface flow in hillslopes. Determinations of Ks,l at the hillslope scale are expected to yield valuable information for interpreting and modeling hydrological processes since soil heterogeneities are functionally averaged in this case. However, these data are rare since the experiments are quite difficult and costly. In this investigation, that was carried out in Sardinia (Italy), large-scale determinations of Ks,l were done in two adjacent hillslopes covered by a Mediterranean maquis and grass, respectively, with the following objectives: i) to evaluate the effect of land use change o…
Quantifying the spatial extent and intensity of recent extreme drought events in the Amazon rainforest and their impacts on the carbon cycle
2020
Over the last decades, the Amazon rainforest was hit by multiple severe drought events. Here we assess the severity and spatial extent of the extreme drought years 2005, 2010, and 2015/2016 in the Amazon region and their impacts on the carbon cycle. As an indicator of drought stress in the Amazon rainforest, we use the widely applied maximum cumulative water deficit (ΔMCWD). Evaluating an ensemble of ten state-of-the-art precipitation datasets for the Amazon region, we find that the spatial extent of the drought in 2005 ranges from 2.8 to 4.2 (mean = 3.2) million km2 (46–71 % of the Amazon basin, mean = 53 %) where ΔMCWD indicates at le…
A real-time non-intrusive FPGA-based drowsiness detection system
2011
Automotive has gained several benefits from the Ambient Intelligent researches involving the deployment of sensors and hardware devices into an intelligent environment surrounding people, meeting users’ requirements and anticipating their needs. One of the main topics in automotive is to anticipate driver needs and safety, in terms of preventing critical and dangerous events. Considering the high number of caused accidents, one of the most relevant dangerous events affecting driver and passengers safety is driver’s drowsiness and hypovigilance. This paper presents a low-intrusive, real-time driver’s drowsiness detection system for common vehicles. The proposed system exploits the ‘‘bright p…
Ģimenes loma bērna attīstībā līdz 3 gadu vecumam
2018
Darba nosaukums: Ģimenes loma bērna attīstībā līdz 3 gadu vecumam Darba autors : Ineta Buka Zinātniskā darba vadītāja: Ērika Vugule Pētījuma darba mērķis : Izpētīt ģimenes nozīmi 3 gadus veca bērna attīstībā. Pētījumā izmantotas šādu autoru atziņas L. Rutkas, D. Dzintares, I. Stangaines, R. Vastas, O. Pisarikas, G. Ņūfelda,. H. Gustavsons, Ļ.Vigotskia, Pētījumā praktiskajā daļā izmantojot anketēšanu, parunas un pedagoģiskā novērojuma metodi tika pārbaudītā vecāku loma, un drošās piesaistes nozīme un 3 g.v bērnu attīstībā. Pētījuma hipotēze par 3 g.v. bērnu psihofizioloģijai un emocionālā attīstība ir sekmēta, ja starp vecākiem un bērniem nodibināta drošā vitālā saite. Ir daļēji apstiprināju…