Search results for "MBL"

Chemical self-organization in self-assembling biomimetic systems

2009

Abstract Far-from-equillibrium oscillating chemical reactions are among the simplest systems showing complex behaviors and emergent properties. This class of reactions is often employed to mimic and understand the mechanisms of a great variety of biological processes. In this context, pattern formation due to the coupling between reaction and transport phenomena represent an active and promising research area. In this paper, we present results coming from experiments where we tried to blend the structural properties of self-assembled matrixes (sodium dodecyl sulphate micelles and phospholipid bilayers) together with the evolutive peculiarities of the Belousov–Zhabotinsky reaction. A series …

The distributed assembly permutation flowshop scheduling problem

2013

Nowadays, improving the management of complex supply chains is a key to become competitive in the twenty-first century global market. Supply chains are composed of multi-plant facilities that must be coordinated and synchronised to cut waste and lead times. This paper proposes a Distributed Assembly Permutation Flowshop Scheduling Problem (DAPFSP) with two stages to model and study complex supply chains. This problem is a generalisation of the Distributed Permutation Flowshop Scheduling Problem (DPFSP). The first stage of the DAPFSP is composed of f identical production factories. Each one is a flowshop that produces jobs to be assembled into final products in a second assembly stage. The o…

On the checking of g-coherence of conditional probability bounds

2003

We illustrate an approach to uncertain knowledge based on lower conditional probability bounds. We exploit the coherence principle of de Finetti and a related notion of generalized coherence (g-coherence), which is equivalent to the "avoiding uniform loss" property introduced by Walley for lower and upper probabilities. Based on the additive structure of random gains, we define suitable notions of non relevant gains and of basic sets of variables. Exploiting them, the linear systems in our algorithms can work with reduced sets of variables and/or constraints. In this paper, we illustrate the notions of non relevant gain and of basic set by examining several cases of imprecise assessments d…

The European contribution to the development and validation activities for the design of IFMIF lithium facility

2013

The International Fusion Materials Irradiation Facility (IFMIF) is an accelerator-driven intense neutron source where candidate materials for fusion reactors will be tested and validated. The high energy neutron flux is produced by means of two deuteron beams (total current of 250 mA, energy of 40 MeV) that strikes a liquid lithium target circulating in a lithium loop of IFMIF plant. The European (EU) contribution to the development of the lithium facility comprises five procurement packages, as follow: (1) participation to the experimental activities of the EVEDA lithium test loop in Oarai (Japan); (2) study aimed at evaluating the corrosion and erosion phenomena, promoted by lithium, for …

Programmable assembly of peptide amphiphile via noncovalent-to-covalent bond conversion

2017

Controlling the number of monomers in a supramolecular polymer has been a great challenge in programmable self-assembly of organic molecules. One approach has been to make use of frustrated growth of the supramolecular assembly by tuning the balance of attractive and repulsive intermolecular forces. We report here on the use of covalent bond formation among monomers, compensating for intermolecular electrostatic repulsion, as a mechanism to control the length of a supramolecular nanofiber formed by self-assembly of peptide amphiphiles. Circular dichroism spectroscopy in combination with dynamic light scattering, size-exclusion chromatography, and transmittance electron microscope analyses r…

Dynamic DNA Origami Devices

2018

DNA nanotechnology provides an excellent foundation for diverse nanoscale structures that can be used in various bioapplications and materials research. Among all existing DNA assembly techniques, DNA origami proves to be the most robust one for creating custom nanoshapes. Since its invention in 2006, building from the bottom up using DNA advanced drastically, and therefore, more and more complex DNA-based systems became accessible. So far, the vast majority of the demonstrated DNA origami frameworks are static by nature; however, there also exist dynamic DNA origami devices that are increasingly coming into view. In this review, we discuss DNA origami nanostructures that exhibit controlled…

Self-assembly of catalytically-active supramolecular coordination compounds within metal-organic frameworks

2019

[EN] Supramolecular coordination compounds (SCCs) represent the power of coordination chemistry methodologies to self-assemble discrete architectures with targeted properties. SCCs are generally synthesized in solution, with isolated fully coordinated metal atoms as structural nodes, thus severely limited as metal-based catalysts. Metal-organic frameworks (MOFs) show unique features to act as chemical nanoreactors for the in situ synthesis and stabilization of otherwise not accessible functional species. Here, we present the self-assembly of Pd-II SCCs within the confined space of a pre-formed MOF (SCCs@MOF) and its post-assembly metalation to give a Pd-II-Au-III supra molecular assembly, c…

Varianti alleliche del gene per la lectina legante il mannosio (MBL): Un vantaggio o uno svantaggio per la longevità?

2010

Search strategies for ensemble feature selection in medical diagnostics

2003

The goal of this paper is to propose, evaluate, and compare four search strategies for ensemble feature selection, and to consider their application to medical diagnostics, with a focus on the problem of the classification of acute abdominal pain. Ensembles of learnt models constitute one of the main current directions in machine learning and data mining. Ensembles allow us to get higher accuracy, sensitivity, and specificity, which are often not achievable with single models. One technique, which proved to be effective for ensemble construction, is feature selection. Lately, several strategies for ensemble feature selection were proposed, including random subspacing, hill-climbing-based se…

Rabbit: More than the Magdalenian main dish in the Iberian Mediterranean region. New data from Cova de les Cendres (Alicante, Spain)

2020

Abstract In the Mediterranean Iberian region, rabbit has an important role in the human diet, mainly during the Final Upper Palaeolithic. The archaeological and experimental works about rabbit processing and consumption from the last years provide a wide and relevant framework. The site of Cova de les Cendres (Alicante, Spain) has a relevant role in the knowledge of the Iberian Upper Palaeolithic human subsistence, and offer a wide chronological sequence. The Magdalenian levels of Cendres provide a well-preserve archaeological assemblage of rabbit remains (ca. 90% of the total fauna) to study the human behaviour. The results show subsistence activities focus not only on meat and marrow imme…