Search results for "MBL"
showing 10 items of 1636 documents
Comparing Boosting and Bagging for Decision Trees of Rankings
2021
AbstractDecision tree learning is among the most popular and most traditional families of machine learning algorithms. While these techniques excel in being quite intuitive and interpretable, they also suffer from instability: small perturbations in the training data may result in big changes in the predictions. The so-called ensemble methods combine the output of multiple trees, which makes the decision more reliable and stable. They have been primarily applied to numeric prediction problems and to classification tasks. In the last years, some attempts to extend the ensemble methods to ordinal data can be found in the literature, but no concrete methodology has been provided for preference…
Solid film versus solution-phase charge-recombination dynamics of exTTF-bridge-C60 dyads.
2005
The charge-recombination dynamics of two exTTF-C 6 0 dyads (exTTF=9,10-bis(l,3-dithiol-2-ylidene)-9,10-dihydroanthracene), observed after photoinduced charge separation, are compared in solution and in the solid state. The dyads differ only in the degree of conjugation of the bridge between the donor (exTTF) and the acceptor (C 6 0 ) moieties. In solution, photoexcitation of the nonconjugated dyad C 6 0 -BN-exTTF (1) (BN=1,1'-binaphthyl) shows slower charge-recombination dynamics compared with the conjugated dyad C 6 0 -TVB-exTTF (2) (TVB = bisthienylvinylenebenzene) (lifetimes of 24 and 0.6 μs, respectively), consistent with the expected stronger electronic coupling in the conjugated dyad.…
Alimentare sogni, destrutturare speranze. Politiche di offerta e dinamica della domanda di gioco aleatorio nell’Italia contemporanea
2013
I dati sul coinvolgimento degli italiani nel consumo di giochi di tipo alea (gambling in genere, scommesse, lotterie ecc.) evidenziano come negli ultimi dieci anni la pratica della “scommessa” sia diventata oltremodo diffusa. A questa crescita ha certamente contribuito, oltre alla crisi congiunturale richiamata da alcuni studiosi quale causa contingente, sia l‘aumento dell’offerta di gioco, cresciuta notevolmente rispetto al passato e in Italia fondamentalmente gestita dal monopolio statale, sia la maggiore accessibilità consentita dalle nuove tecnologie della comunicazione. Nell’intervento si descrive lo stato attuale della domanda e dell’offerta del consumo di gioco, prendendo in consider…
Diimidazolium-based organic salts as low molecular weight hydro- and organogelator
Orthosis to reduce essential tremor
2013
[EN] The Institute of Biomechanics (IBV) coordinated the technical development of an orthesis to reduce essential tremor. The Valencian company EMO coordinated this European project called TREMEND. Furthermore, the companies Cultraro and OKO Solution, the research centre ISRI and the Neurology Service of Hospital General Universitario de Valencia collaborated in this project. The results show that the orthosis is effective and it reduces essential tremor in the wrist about 30 %, allowing affected people increase their degree of independence.
Oxidative modification and breakdown of ribulose-1,5-bisphosphate carboxylase/oxygenase induced in Euglena gracitis by nitrogen starvation
1994
When photoheterotrophic Euglena gracilis Z Pringsheim was subjected to nitrogen (N)-deprivation, the abundant photosynthetic enzyme ribulose-1,5-bis-phosphate carboxylase/oxygenase (Rubisco; EC 4.1.1.39) was rapidly and selectively degraded. The breakdown began after a 4-h lag period and continued for a further 8 h at a steady rate. After 12 h of starvation, when the amount of Rubisco was reduced to 40%, the proteolysis of this enzyme slowed down while degradation of other proteins started at a similar pace. This resulted in a decline of culture growth, chloroplast disassembly — as witnessed by chlorophyll (Chl) loss — and cell bleaching. Experiments with spectinomycin, an inhibitor of chlo…
MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate
2019
Polo-like kinase (PLK1) has been identified as a potential target for cancer treatment. Although a number of small molecules have been investigated as PLK1 inhibitors, many of which showed limited selectivity. PLK1 harbors a regulatory domain, the Polo box domain (PBD), which has a key regulatory function for kinase activity and substrate recognition. We report on 3-bromomethyl-benzofuran-2-carboxylic acid ethyl ester (designated: MCC1019) as selective PLK1 inhibitor targeting PLK1 PBD. Cytotoxicity and fluorescence polarization-based screening were applied to a library of 1162 drug-like compounds to identify potential inhibitors of PLK1 PBD. The activity of compound MC1019 against the PLK1…
SMOOTHLY SHIFTING FLUORESCENT WINDOW: TUNABLE “OFF-ON-OFF” MICELLAR BIOSENSORS FOR pH
2009
Mākslinieciskās izteiksmes līdzekļi Pablo Pikaso sintētiskā kubisma perioda asamblāžās un to izmantošanas iespējas vizuālās mākslas stundās 5. klasē
2021
Diplomdarba temats ir „Mākslinieciskās izteiksmes līdzekļi Pablo Pikaso sintētiskā kubisma perioda asamblāžās un to izmantošanas iespējas vizuālās mākslas stundās 5. klasē” Darbs izstrādāts ar mērķi izpētīt mākslinieciskās izteiksmes līdzekļu Pablo Pikaso sintētiskā kubisma kolāžās un asamblāžās izmantošanas iespējas vizuālās mākslās stundās 5. klasē. Darba ietvaros sniegts ieskats P. Pikaso biogrāfijā, raksturoti viņa radošā darba posmi, īpaši akcentējot kubisma periodā izmantotos vizuālās izteiksmes līdzekļus, tai skaitā kolāžas un asamblāžas. Noteikti vizuālās mākslas stundu organizācijas metodoloģiskie pamati, ņemot vērā 5.klašu skolēnu vecumposma īpatnības. Empīriskajā daļā izstrādāta …
Una asociación peculiar de fusulinas en las calizas de Tanes, sección de Campo de Caso (Pensilvánico, Moscoviense superior; zona Cantábrica, España)
2021
The Campo de Caso section (eastern part of the Cantabrian Zone, NW Spain) exposes a middle to upper Moscovian (Middle Pennsylvanian) succession, up to 3500-m thick, consisting of marine shelfal and deltaic siliciclastic and shale deposits with numerous intercalated fossiliferous limestones. A limestone outcropping in the upper part of this section, close to the village of Tanes, has yielded a fusuline assemblage composed of species of the genera Eostaffella, Pseudonovella, Ozawainella, Pseudostaffella, Neostaffella, Schubertella, Fusiella, Taitzehoella, Fusulinella, Beedeina and Putrella . The specific composition of these genera, considered as a whole, indicates an early to mid- Myachkov…