Search results for "MECHANISMS"

showing 10 items of 587 documents

Plexin-B1 activates NF-κB and IL-8 to promote a pro-angiogenic response in endothelial cells.

2011

Background The semaphorins and their receptors, the plexins, are proteins related to c-Met and the scatter factors that have been implicated in an expanding signal transduction network involving co-receptors, RhoA and Ras activation and deactivation, and phosphorylation events. Our previous work has demonstrated that Semaphorin 4D (Sema4D) acts through its receptor, Plexin-B1, on endothelial cells to promote angiogenesis in a RhoA and Akt-dependent manner. Since NF-κB has been linked to promotion of angiogenesis and can be activated by Akt in some contexts, we wanted to examine NF-κB in Sema4D treated cells to determine if there was biological significance for the pro-angiogenic phenotype o…

animal structuresRHOAProto-Oncogene Proteins c-aktAngiogenesisSignaling in cellular processesG-protein signalingCancer TreatmentSEMA4Dlcsh:MedicineSignal transductionBiology03 medical and health sciencesMolecular cell biology0302 clinical medicineSemaphorinSettore BIO/10 - BiochimicaAkt Signaling CascadeMembrane Receptor SignalingInterleukin 8lcsh:ScienceBiologyProtein kinase BGTPase signalingRas signaling030304 developmental biology0303 health sciencesMultidisciplinaryMechanisms of Signal Transductionlcsh:RSignaling Cascades3. Good healthCell biologyPlexin B1RNA interferencepro-angiogenicendothelial cellsOncology030220 oncology & carcinogenesisembryonic structuresCancer researchbiology.proteinMedicinelcsh:QAntiangiogenesis TherapyAntiapoptotic signalingSignal transductionResearch ArticlePLoS ONE
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Courtship song and immune function in the field cricket Gryllus bimaculatus

2003

It has been assumed that sexual ornaments have evolved to reveal males’ health and vigour for females. Choosy females may indirectly use ornaments as an indicator of the presence and effectiveness of genes for resistance against parasites. In this study we tested whether females of the Mediterranean field cricket, Gryllus bimaculatus, can use courtship song as a cue for choosing males with high immunocompetence, measured as encapsulation rate of nylon implants and lytic activity of haemolymph. We found that female crickets preferred courtship songs from males with a high encapsulation rate. Female crickets also had a tendency to prefer courtship songs with high tick rate and long high-frequ…

animal structuresbiologyCourtship displayOrthopteraEcologymedia_common.quotation_subjectGryllus bimaculatusZoologybiology.organism_classificationCantoCourtshipField cricketCricketSexual selectionbehavior and behavior mechanismsreproductive and urinary physiologypsychological phenomena and processesEcology Evolution Behavior and Systematicsmedia_commonBiological Journal of the Linnean Society
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Conditioned Pain Modulation Is Not Impaired in Individuals with Frozen Shoulder: A Case-Control Study

2021

Frozen shoulder (FS) is a poorly understood condition resulting in substantial shoulder pain and mobility deficits. The mechanisms behind FS are not yet fully understood, but, similar to other persistent pain states, central pain mechanisms may contribute to ongoing symptoms in this population. The objective of this research was to investigate conditioned pain modulation (CPM) in people with FS compared with pain-free individuals. A total of 64 individuals with FS and 64 healthy volunteers participated in this cross-sectional study. CPM was assessed by using the pressure pain threshold (PPT) and an occlusion cuff (tourniquet test) as the test and conditioning stimulus, respectively. The abs…

assessmentHealth Toxicology and MutagenesisPopulationPainStimulus (physiology)ArticleBursitisOcclusionHumansconditioned pain modulationMedicinefrozen shouldereducationPain Measurementeducation.field_of_studybusiness.industryPharmacology. TherapyRPublic Health Environmental and Occupational HealthChronic painCase-control studyFrozen shoulderfrozen shoulder; conditioned pain modulation; inhibitory endogenous pain mechanisms; chronic pain; assessmentmedicine.diseaseCross-Sectional StudiesConditioned pain modulationCase-Control StudiesAnesthesiaMedicineTourniquet testHuman medicineinhibitory endogenous pain mechanismschronic painbusinessInternational Journal of Environmental Research and Public Health
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The Approach Behavior to Angry Words in Athletes : A Pilot Study

2019

An increasing number of studies have found that athletes have a higher level of aggression than non-athletes. Anger is an important factor in the generation of aggressive behavior, and anger has been found to relate to both approach behavior and avoidance behavior. The present pilot study compared the aggression level of athletes and non-athletes using the Buss-Perry Aggression Questionnaire, and examined the responses of participants to anger-related stimuli using the manikin task, a paradigm that measures approach-avoidance behavior. In total, 15 athletes and 15 non-athletes finished the questionnaire and the manikin task, which included two conditions. In the anger approach condition, pa…

athletesaggressiivisuusmental disordersangerbehavior and behavior mechanismstheta oscillationbehavioral approach systemvihamielisyysaggressive behaviorkäyttäytyminenbehavioral disciplines and activitiespsychological phenomena and processesurheilijat
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Memory degradation induced by attention in recurrent neural architectures

2022

This paper studies the memory mechanisms in recurrent neural architectures when attention models are included. Pure-attention models like Transformers are more and more popular as they tend to outperform models with recurrent connections in many different tasks. Our conjecture is that attention prevents the recurrent connections from transferring information properly between consecutive next steps. This conjecture is empirically tested using five different models, namely, a model without attention, a standard Loung attention model, a standard Bahdanau attention model, and our proposal to add attention to the inputs in order to fill the gap between recurrent and parallel architectures (for b…

attention mechanismsrecurrenceArtificial IntelligenceCognitive Neurosciencelong short-term memory networksgate activationsUNESCO::CIENCIAS TECNOLÓGICASComputer Science Applicationsforget gate
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Supplementary results from Evolution of male and female choice in polyandrous systems

2017

Model results for high population density, expensive mate choice, and fixed male mating costs

behavior and behavior mechanismshealth care economics and organizationsreproductive and urinary physiology
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Processing of metals and metalloids by actinobacteria: Cell resistance mechanisms and synthesis of metal(loid)-based nanostructures

2020

Metal(loid)s have a dual biological role as micronutrients and stress agents. A few geochemical and natural processes can cause their release in the environment, although most metal-contaminated sites derive from anthropogenic activities. Actinobacteria include high GC bacteria that inhabit a wide range of terrestrial and aquatic ecological niches, where they play essential roles in recycling or transforming organic and inorganic substances. The metal(loid) tolerance and/or resistance of several members of this phylum rely on mechanisms such as biosorption and extracellular sequestration by siderophores and extracellular polymeric substances (EPS), bioaccumulation, biotransformation, and me…

biogenic nanoscale materials0301 basic medicineMicrobiology (medical)Siderophore010501 environmental sciencesSettore BIO/19 - Microbiologia Generale01 natural sciencesMicrobiologycomplex mixturesActinobacteria03 medical and health sciencesmetal resistance mechanismsBioremediationExtracellular polymeric substanceBiotransformationMetal stress responseVirologyBiogenic nanoscale materialBioprocesslcsh:QH301-705.5Settore CHIM/02 - Chimica Fisica0105 earth and related environmental sciencesbiologyChemistrybiology.organism_classificationActinobacteria030104 developmental biologylcsh:Biology (General)BioaccumulationEnvironmental chemistryMetal resistance mechanismbacteriaMetalloidMetal-based nanostructures
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Determinants of the Mating Success of Polyterritorial Pied Flycatcher Males

2010

Much attention has been paid to the polyterritorial mating system of some passerine birds. Here we report how a male's mating success is related to the behavioral traits of polyterritorial pied flycatcher (Ficedula hypoleuca) males. We found no evidence that the timing of polyterritoriality in relation to egg laying in the primary nest or the singing behavior of males have any influence on mating success. However, results show clearly that male mating success was improved with an increase in the distance between territories up to a distance of about 200–300 m whereupon there was no further enhancement of mating success. This finding is crucial for both the deception hypothesis and female-fe…

biologyEcologyFicedulabiology.organism_classificationMating systemCantoPasserineMate choicebiology.animalbehavior and behavior mechanismsAnimal Science and ZoologyAnimal communicationMatingPolygynyEcology Evolution Behavior and SystematicsDemographyEthology
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Predatory behavior in the genusLeptogenys: A comparative study

1997

We studied the predatory behavior of seven species of the genusLeptogenys from Mexico and Cameroon. The ants of this genus are armed with long, thin, curved mandibles articulated at the extreme corners of the anterior margin of the head, permitting them easily to seize oniscoid isopods, the obligate or the principal prey of mostLeptogenys species. Workers hunt these prey, which are able to roll themselves up, solitarily. Foraging behavior comprises sequences of up to eight activities. The prey can be seized by the body (rolled up or not), or alternatively by the edge of the shell, then turned over and stung on the ventral face. A relationship between the mandible size of the workers and the…

biologyEcologyForagingHymenopterabiology.organism_classificationAttractionPredationMandible (arthropod mouthpart)LeptogenysAculeataAnimal ecologyInsect Sciencebehavior and behavior mechanismsEcology Evolution Behavior and SystematicsJournal of Insect Behavior
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Food availability and the male's role in parental care in double-brooded TreecreepersCerthia familiaris

1996

The aim of this work was to examine differences in paternal and maternal care in a double-brooded, monogamous species, the Treecreeper Certhia familiaris, in relation to food availability. As a measure of parental care, we recorded the hourly feeding activity of parents when the nestlings from their first and second breeding attempts were 7 and 12 days old. Feeding frequency of the first brood increased with the age of the nestlings and also with the brood size when 12 days old. While the feeding activities of the females were similar with respect to the first and second broods, the males were less active and failed to provide any food to their nestlings in 15 cases out of 28 second broods.…

biologyFood availabilityEcologyCerthia familiarisbiology.organism_classificationBroodAltricialFood supplybehavior and behavior mechanismsSeasonal breederAnimal Science and ZoologyTreecreeperPaternal carereproductive and urinary physiologyEcology Evolution Behavior and SystematicsDemographyIbis
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