Search results for "MEG"

Globorotalia truncatulinoides in the Mediterranean Basin during the Middle–Late Holocene: Bio-Chronological and Oceanographic Indicator

2022

The planktonic foraminiferal species Globorotalia truncatulinoides is widely used as a biostratigraphic proxy for the Quaternary in the Mediterranean region. High-resolution quantitative studies performed on sediment cores collected in the central and western Mediterranean Sea evidence a significant abundance of G. truncatulinoides during the Middle Holocene. The robust chronological frame allows us to date this bio-event to 4.8–4.4 ka Before Present (BP), very close to the base of the Meghalayan stage (4.2 ka BP). As a consequence, we propose that G. truncatulinoides can be considered a potential marker for the Middle–Late Holocene chronological subdivision. G. truncatulinoides is a deep-d…

Ameglio, Giovanni (Palermo 1854 - Roma 1921), Generale, Senatore

2008

Governatore della Tripolitania e della Cirenaica durante e poco dopo il primo conflitto mondiale (periodo in cui si pongono le basi per le nuove urbanizzazioni delle città costiere della Libia), Ameglio è uno dei principali protagonisti delle spedizioni militari dei primi quattro decenni di espansionismo coloniale italiano. L’eco delle sue gesta d’oltremare contribuì non poco al rilancio in Sicilia del gusto per l’orientalismo e per le arabisances sia nell’arredo e nella decorazione degli interni sia in architettura (fra le tante opere di questa tendenza ricordiamo il chiosco di E. Armò in via Roma del 1912, dedicato alla sua celebre vittoria passata alla storia come “Battaglia delle Due Pa…

Alterazioni del metabolismo glucidico determinate da eccesso di ormoni contro regolatori.

2010

Buon compenso glicemico nei pazienti acromegalici affetti da diabete secondario.

2010

Increated central corneal thickness in acromegalic patients

2009

No effect of GH/IGF-1 excess on adrenal gland in Acromegalic patients.

2007

GH-suppression test in acromegaly: comparison between OGTT and chocolate test

2005

Treatment results of acromegaly as analyzed by different criteria.

1997

Results of treatment of acromegaly are often incomparable due to the different criteria which have been used for defining cure or control of disease. At the present time it is widely accepted, that the main criteria of cure must be normalization of IGF-1 and a GH in the OGTT2 ng/ml. In this retrospective study we investigated the endocrinological results of 56 patients, who were surgically treated because of a GH-producing pituitary adenoma, by different criteria. Twelve of our patients had had additional medical treatment after surgery, two received radiotherapy. At a mean follow-up of 34 months after surgery 66% of patients had a basal GH5 ng/ml, 64% had a GH in the OGTT2 ng/ml and 73% ha…

Cytomegalovirus Misleads Its Host by Priming of CD8 T Cells Specific for an Epitope Not Presented in Infected Tissues

2003

Cytomegaloviruses (CMVs) code for several proteins that inhibit the presentation of antigenic peptides to CD8 T cells. Although the molecular mechanisms of CMV interference with the major histocompatibility complex class I pathway are long understood, surprisingly little evidence exists to support a role in vivo. Here we document the first example of the presentation of an antigenic peptide being blocked by a CMV immune evasion protein in organs relevant to CMV disease. Although this Db-restricted peptide, which is derived from the antiapoptotic protein M45 of murine CMV (mCMV), is classified as an immunodominant peptide based on response magnitude and long-term memory, adoptive transfer of…

Subdominant CD8 T-Cell Epitopes Account for Protection against Cytomegalovirus Independent of Immunodomination▿ †

2008

ABSTRACTCytomegalovirus (CMV) infection continues to be a complication in recipients of hematopoietic stem cell transplantation (HSCT). Preexisting donor immunity is recognized as a favorable prognostic factor for the reconstitution of protective antiviral immunity mediated primarily by CD8 T cells. Furthermore, adoptive transfer of CMV-specific memory CD8 T (CD8-TM) cells is a therapeutic option for preventing CMV disease in HSCT recipients. Given the different CMV infection histories of donor and recipient, a problem may arise from an antigenic mismatch between the CMV variant that has primed donor immunity and the CMV variant acquired by the recipient. Here, we have used the BALB/c mouse…