Search results for "METAL"

showing 10 items of 7908 documents

Role of proinflammatory alleles in longevity and atherosclerosis: results of studies performed on -1562C/T MMP-9 in centenarians and myocardial infar…

2007

Centenarians are characterized by marked delay or escape from age-associated diseases that cause mortality at earlier ages. Jointly, atherosclerosis and its complications, such as myocardial infarction (AMI), significantly contribute to mortality in the elderly. Inflammation is a key component of atherosclerosis and inflammatory genes are good candidates for the risk of the development of atherosclerosis. Genetic traits contribute to the risk of AMI and allelic variations in inflammatory genes should boost the risk of disease. If proinflammatory genotypes significantly contribute to the risk of AMI, alleles associated with disease susceptibility should not be included in the genetic backgro…

AdultMalemedia_common.quotation_subjectLongevityMyocardial InfarctionInfarctionInflammationSingle-nucleotide polymorphismDiseaseCoronary Artery DiseaseBiologyPolymorphism Single NucleotideGeneral Biochemistry Genetics and Molecular BiologyProinflammatory cytokineCohort StudiesMetalloproteaseHistory and Philosophy of ScienceGene FrequencymedicineSNPHumansAllelePolymorphismSicilyAllelesmedia_commonAged 80 and overInflammationGeneral NeuroscienceLongevityMiddle Agedmedicine.diseaseMatrix Metalloproteinase 9InfarctionImmunologyFemalemedicine.symptomAnnals of the New York Academy of Sciences
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EPIDEMIOLOGICAL SURVEILLANCE OF VISCERAL LEISHMANIASIS IN SICILY, ITALY

1997

Abstract Visceral leishmaniasis (VL) is endemic in Sicily. Although it is a notifiable disease, there is evidence that the actual number of cases is higher than that reported. In 1987, a regional reference center for active surveillance of VL was established and it recorded a total of 284 cases through 1995, a mean of 31.5 cases/year and about four-fold more than previously reported. Of the 284 cases, 150 (53%) were children (≤ 14 years of age), and of the 134 adults, 39 (29%) were coinfected with human immunodeficiency virus (HIV). The commonest viscerotropic zymodeme of Leishmania infantum, MON 1, was identified in 40 (93%) of 43 HIV-negative and eight (57%) of 14 HIV-positive patients. A…

AdultMalemedicine.medical_specialtyAdolescentAllopurinolMeglumine antimoniateNotifiable diseaseAntiprotozoal AgentsHIV InfectionsCohort StudiesAge DistributionMeglumineRecurrenceAmphotericin BVirologyInternal medicineAmphotericin BEpidemiologyOrganometallic CompoundsmedicineAnimalsHumansLeishmania infantumSex DistributionChildSicilyleishmaniasisAgedMeglumine Antimoniatebiologybusiness.industryInfantLeishmaniasisMiddle Agedbiology.organism_classificationmedicine.diseaseSurgeryInfectious DiseasesVisceral leishmaniasisChild PreschoolLeishmaniasis VisceralAntimonialDrug Therapy CombinationFemaleParasitologyLeishmania infantumbusinessmedicine.drug
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MRI findings in lingual venous malformations.

2003

To describe the plain and enhanced MRI findings of lingual venous malformations and to discuss the importance of contrast medium in the differential diagnosis of high intensity lesions of the tongue on T(2) weighted images.The clinical records and MR images of eight patients affected by a lingual venous malformation were retrospectively reviewed. Patients presented with a palpable submucosal bluish-red soft mass in the tongue. MRI examinations were performed on a 0.5 T superconducting unit. Plain and enhanced SE (spin echo) T(1) weighted and FSE (fast spin echo) T(2) weighted images were acquired in axial, sagittal and coronal planes. Axial SPGR (spoiled gradient recalled echo) T(1) weighte…

AdultMalemedicine.medical_specialtyAdolescentContrast MediaGadoliniumEpiglottisArteriovenous MalformationsDiagnosis DifferentialMeglumineTongueTip of the tongueTonguemedicineOrganometallic CompoundsHumansRadiology Nuclear Medicine and imagingChildGeneral DentistryMouth FloorRetrospective Studiesmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingGeneral MedicineMiddle AgedSubmandibular spacemedicine.diseaseImage EnhancementMagnetic Resonance ImagingSagittal planeContrast mediummedicine.anatomical_structureOtorhinolaryngologyCoronal planeInjections IntravenousFemaleRadiologybusinessVenous malformationDento maxillo facial radiology
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The association of urine metals and metal mixtures with cardiovascular incidence in an adult population from Spain: the Hortega Follow-Up Study

2019

AbstractBackgroundThe association of low-level exposure to metals and metal mixtures with cardiovascular incidence in the general population has rarely been studied. We flexibly evaluated the association of urinary metals and metal mixtures concentrations with cardiovascular diseases in a representative sample of a general population from Spain.MethodsUrine antimony (Sb), barium (Ba), cadmium (Cd), chromium (Cr), cobalt (Co), copper (Cu), molybdenum (Mo), vanadium (V) and zinc (Zn) were measured in 1171 adults without clinical cardiovascular diseases, who participated in the Hortega Study. Cox proportional hazard models were used for evaluating the association between single metals and card…

AdultMalemedicine.medical_specialtyAdolescentEpidemiologyPopulationchemistry.chemical_elementUrineZinc010501 environmental sciences01 natural sciencesGastroenterologyYoung Adult03 medical and health sciencesChromium0302 clinical medicineMetals HeavyCardiovascular DiseaseInternal medicinemedicineHumans030212 general & internal medicineeducationAged0105 earth and related environmental sciencesAged 80 and overeducation.field_of_studyCadmiumIncidenceIncidence (epidemiology)Hazard ratioBayes TheoremBariumGeneral MedicineMiddle AgedchemistryCardiovascular DiseasesSpainEnvironmental PollutantsFemaleBiomarkersFollow-Up StudiesInternational Journal of Epidemiology
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Colorectal Polyps: Detection with Dark-Lumen MR Colonography versus Conventional Colonoscopy

2005

To prospectively compare dark-lumen magnetic resonance (MR) colonography with conventional colonoscopy in the detection of colorectal polyps.Local ethical committee approval and informed consent were obtained. One hundred consecutive patients (56 men, 44 women; mean age +/- standard deviation, 67.7 years +/- 14.7; range, 25-82 years) who were referred for conventional colonoscopy from January 2003 to January 2004 underwent MR colonography and conventional colonoscopy after standard precolonoscopic bowel cleansing. Colonoscopy was performed immediately after MR colonography. For MR colonography, the colon was filled with approximately 2000 mL of tap water. Imaging was performed with a 1.5-T …

AdultMalemedicine.medical_specialtyColonic PolypsContrast MediaRectumColonoscopySensitivity and SpecificityImaging Three-DimensionalMegluminePredictive Value of TestsImage Processing Computer-AssistedOrganometallic CompoundsmedicineHumansRadiology Nuclear Medicine and imagingProspective StudiesProspective cohort studyAgedAged 80 and overmedicine.diagnostic_testbusiness.industryMr colonographyMagnetic resonance imagingColonoscopyMiddle AgedMagnetic Resonance ImagingEndoscopyProne positionmedicine.anatomical_structurePredictive value of testsFemaleRadiologybusinessRadiology
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A multicenter, site-independent, blinded study to compare the diagnostic accuracy of contrast-enhanced magnetic resonance angiography using 1.0M gado…

2007

Abstract Purpose Prospective evaluation of diagnostic accuracy of single field-of-view contrast-enhanced MR Angiography (ceMRA) with 1.0 M gadobutrol compared to intraarterial DSA in body arteries. Materials and methods In an European multicenter study 179 patients underwent ceMRA and DSA. For each indication five prospectively defined vessel segments were evaluated by local investigators onsite and by three site-independent blinded readers (BR) independently. Results The agreement between ceMRA and DSA diagnosis was statistically significant in the onsite (96.6%) and blinded reader (86.6–90.2%) evaluation. Sensitivity, specificity, accuracy, positive (PPV) and negative predictive values (N…

AdultMalemedicine.medical_specialtyContrast MediaDiagnostic accuracyGadoliniumConstriction PathologicSensitivity and SpecificityMagnetic resonance angiographyGadobutrolmedicineOrganometallic CompoundsHumansRadiology Nuclear Medicine and imagingSingle-Blind MethodProspective StudiesProspective cohort studyAgedAged 80 and overmedicine.diagnostic_testbusiness.industryAngiography Digital SubtractionGeneral MedicineDigital subtraction angiographyArteriesMiddle Agedmedicine.diseasebody regionsStenosismedicine.anatomical_structureAngiographyRadiologyNuclear medicinebusinessMagnetic Resonance Angiographymedicine.drugArteryEuropean journal of radiology
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Diagnostic performance of gadobenate dimeglumine enhanced MR angiography of the iliofemoral and calf arteries: a large-scale multicenter trial

2007

OBJECTIVE. The purpose of this study was to compare gadobenate dimeglumine–enhanced MR angiography and unenhanced time-of-flight MR angiography for the detection of significant peripheral arterial occlusive disease using digital subtraction angiography as our reference standard. SUBJECTS AND METHODS. Two hundred seventy-two patients underwent MR angiography and digital subtraction angiography of the iliofemoral arteries. MR angiography was performed before (2D time-of-flight acquisitions) and after (spoiled gradient-echo acquisitions) the administration of 0.1 mmol/kg of gadobenate dimeglumine at 1–2 mL/s. Contrast-enhanced MR angiography and digital subtraction angiography of the calf arte…

AdultMalemedicine.medical_specialtyContrast MediaLumen (anatomy)Arterial Occlusive DiseasesArterial Occlusive Diseases/*diagnosis Contrast Media Image Enhancement/*methods Magnetic Resonance Angiography/*methods Meglumine/*analogs & derivatives/therapeutic useSensitivity and SpecificityMegluminecontrast agents; diagnostic performance; gadobenate dimeglumine; MR angiography; peripheral arterial occlusive diseasediagnostic performancePeripheral arterial occlusive diseaseMulticenter trialOrganometallic CompoundsHumansMedicineRadiology Nuclear Medicine and imagingcontrast agentsGADOBENATE DIMEGLUMINEAgedPeripheral Vascular DiseasesMR angiographymedicine.diagnostic_testbusiness.industryVascular diseaseMr angiographyReproducibility of ResultsGeneral MedicineDigital subtraction angiographyMiddle AgedSouth Americacontrast agentImage Enhancementmedicine.diseaseEuropemedicine.anatomical_structureThighFemaleRadiologybusinessperipheral arterial occlusive diseaseMagnetic Resonance AngiographyArterygadobenate dimeglumine
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MR angiography of the pedal arteries with gadobenate dimeglumine, a contrast agent with increased relaxivity, and comparison with selective intraarte…

2007

Purpose To compare gadobenate dimeglumine (Gd-BOPTA)–enhanced MR angiography (i.e., contrast-enhanced MRA [CE-MRA]) of the pedal vasculature with selective digital subtraction angiography (DSA) in patients with peripheral arterial occlusive disease (PAOD). Materials and Methods A total of 22 patients with PAOD were prospectively examined at 1.5T. For contrast enhancement, 0.1 mmol/kg body weight of Gd-BOPTA were applied. MRA consisted of dynamic imaging with acquisition of six consecutive data sets. Acquisition time for each data set was 24 seconds, voxel size was 1.0 × 1.0 × 1.3 mm3. A total of 20 out of 22 patient underwent selective DSA, two patients fine-needle DSA. DSA and MRA were per…

AdultMalemedicine.medical_specialtyImage qualitymedia_common.quotation_subjectDynamic imagingContrast MediaArterial Occlusive DiseasesMegluminemedicineOrganometallic CompoundsContrast (vision)HumansRadiology Nuclear Medicine and imagingIn patientcardiovascular diseasesProspective StudiesGADOBENATE DIMEGLUMINEVascular Patencymedia_commonAgedAged 80 and overPeripheral Vascular Diseasesmedicine.diagnostic_testbusiness.industryFootMr angiographyAngiography Digital SubtractionDigital subtraction angiographyMiddle Agedmedicine.diseasebody regionsStenosiscardiovascular systemFemaleRadiologyNuclear medicinebusinessMagnetic Resonance Angiographycirculatory and respiratory physiologyJournal of magnetic resonance imaging : JMRI
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Gastric emptying of indigestible tablets in relation to composition and time of ingestion of meals studied by metal detector.

1991

Enteric-coated tablets leave the stomach mainly during the interdigestive phase. Composition as well as time of ingestion of meals may influence their gastric emptying considerably. In 12 normal volunteers gastric emptying of a plastic tablet with a metal core was followed by a metal detector in relation to different compositions and various times of ingestion of meals. With an empty stomach and after ingestion of 250 ml water, the mean time for gastric emptying of the tablet was 38 +/- 11 min (mean +/- SEM) and 38 +/- 8 min. Two hundred fifty milliliters of milk (652 kJ) and a formula diet (1000 kJ) delayed gastric emptying time to 128 +/- 14 and 152 +/- 6 min, respectively (P less than 0.…

AdultMalemedicine.medical_specialtyPhysiologyGastroenterologyEatingInternal medicinemedicineIngestionHumansEnteric coatedEating habitsMorningGastric emptyingbusiness.industryStomachdigestive oral and skin physiologyGastroenterologyMiddle AgedBioavailabilitymedicine.anatomical_structureGastric EmptyingFoodMetalsComposition (visual arts)FemaleTablets Enteric-CoatedbusinessDigestive diseases and sciences
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Assessment of atrial diastolic function in patients with hypertrophic cardiomyopathy by cine magnetic resonance imaging

2015

Purpose: This study was conducted to assess the role of atrial function by cardiac magnetic resonance (CMR) for the evaluation of diastolic physiology in patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls. Materials and methods: We enrolled 23 consecutive patients affected by HCM and 43 healthy subjects as age-matched control cases (CC). CMR was performed through acquisition of cine steady-state free precession sequences using a 1.5-T scanner. Image postprocessing was carried out using Tracking Tool software. Results: Atrial volumes were significantly higher in patients with HCM compared to CC: maximum atrial volume (p = 0.007) and minimum atrial volume (p = 0.01).…

AdultMalemedicine.medical_specialtyRadiology Nuclear Medicine and ImagingDiastolic functionCardiac magnetic resonanceDiastoleContrast MediaMagnetic Resonance Imaging CineDiastoleInternal medicineImage Interpretation Computer-AssistedmedicineOrganometallic CompoundsHumansIn patientDiastolic functioncardiovascular diseasesHeart AtriaNeuroradiologyOrganometallic Compoundmedicine.diagnostic_testbusiness.industryMedicine (all)UltrasoundAtrial functionHypertrophic cardiomyopathyMagnetic resonance imagingInterventional radiologyGeneral MedicineCardiomyopathy Hypertrophicmedicine.diseaseHypertrophic cardiomyopathyCase-Control Studiescardiovascular systemCardiologyFemalebusinessCase-Control StudieSettore MED/36 - Diagnostica Per Immagini E RadioterapiaHuman
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