Search results for "MF"
showing 10 items of 3003 documents
The prognostic and predictive role of tumor-infiltrating lymphocytes (FoxP3 + and CD8 +) and tumor-associated macrophages in early HER2 + breast canc…
2023
Purpose In HER2-positive (HER2 +) breast cancer, tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) may influence the efficacy of the HER2-antibody trastuzumab and the patient’s outcome. In this HER2 + patient cohort, our aim was to study the numbers of FoxP3 + regulatory TILs and CD8 + cytotoxic TILs, their correlations with CD68 + and CD163 + TAMs, and the prognostic and predictive value of the studied factors. Methods We evaluated 139 non-metastatic HER2 + breast cancer patients operated between 2001 and 2008. The FoxP3+TIL count (FoxP3+TILs) was assessed using the hotspot method, and the CD8 + TIL count (CD8+mTILs) utilizing a digital image analysis from invas…
Oral-Health-Related Quality of Life and Cosleeping: The Role of Nocturnal Breastfeeding
2021
The purpose of this paper is to analyse the association between cosleeping and the number of breastfeeding sessions in infants, OHRQoL of the child and the family, and the DMFT Child’s index. The sample comprised 273 children (2–4 years old). In addition to the clinical examination of the child to assess the DMFT Index, the mother was requested to complete a questionnaire to collect data about the breastfeeding practice, diet, dental hygiene, dental check-ups, quality of the child’s oral life, and family impact (ECOHIS Scale). The children’s OHRQoL is positively correlated with number of night-time breastfeeding sessions at 12 months (r2 = 0.40 **), DMFT index (r2 = 0.60 **), impact family …
Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes
2021
Background: White adipose tissue (WAT) browning is a promising target for obesity prevention and treatment. Empagliflozin has emerged as an agent with weight-loss potential in clinical and in vivo studies, but the mechanisms underlying its effect are not fully understood. Here, we investigated whether empagliflozin could induce WAT browning and mitochondrial alterations in KK Cg-Ay/J (KKAy) mice, and explored the mechanisms of its effects.Methods: Eight-week-old male KKAy mice were administered empagliflozin or saline for 8 weeks and compared with control C57BL/6J mice. Mature 3T3-L1 adipocytes were treated in the presence or absence of empagliflozin. Mitochondrial biosynthesis, dynamics, a…
Brukeradopsjon av ACOS Individuell plan hos plankoordinatorene : En studie med kombinerte metoder om påvirkningsfaktorer for plankoordinatorenes bruk…
2018
Masteroppgave i helse- og sosialinformatikk HSI500 - Universitetet i Agder 2018 Individual care plan is a comprehensive plan to assist users in need of long-term and coordinated services. Individual care plan is one of several service areas in the municipality digitized for better flow of work procedures, lower costs and increased user involvement. The ACOS IP program enables electronic IP in the municipalities. The study has investigated which main factors affect the plan coordinators user adoption of ACOS IP. User adoption looks at why and how a program is used. The purpose is to look at it from the plan coordinator's perspective, but also how the management at the coordinating unit's fra…
Green Roofs as Effective Tools for Improving the Indoor Comfort Levels of Buildings—An Application to a Case Study in Sicily
2020
In the line of pursuing better energy efficiency in human activities that would result in a more sustainable utilization of resources, the building sector plays a relevant role, being responsible for almost 40% of both energy consumption and the release of pollutant substances in the atmosphere. For this purpose, techniques aimed at improving the energy performances of buildings&rsquo
A systematic literature review on cyberstalking : An analysis of past achievements and future promises
2020
Individuals’ excessive use of technology-enabled communication platforms, such as social media, has led to scholarly recognition of rising incidences of cyberstalking. Despite considerable studies directed at its examination, the current research on cyberstalking is limited by a lack of clarity on its characterization and prevalence, coupled with a fragmented research focus. To address this limitation, a Systematic Literature Review (SLR) on cyberstalking has been undertaken. Rigorous protocols were applied to identify 49 empirical studies via Scopus and Web of Science, based on specific keywords and article selection criteria. Findings reveal four emergent research themes on characteristic…
A Trust-Based Crowdfunding Campaign Marketing Framework: Theoretical Underpinnings and Big-Data Analytics Practice
2021
Towards a critical understanding of data visualisation in democracy: a deliberative systems approach
2021
Data and data visualisations – in the forms of graphs, charts and maps – are becoming an increasingly important feature of social, public and political life. Yet within existing scholarship, the democratic significance of data visualisations has thus far received minimal attention. This article offers a first systematic attempt to make sense of and scrutinise the role of data visualisation in democracy. We apply deliberative systems theory in the analysis of three original case studies to elucidate how data visualisation can integrate into the overall anatomy of democracy, and to normatively assess how data visualisation contributes towards key democratic ideals. Conclusively, we highlight …
Factors influencing the adoption postponement of mobile payment services in the hospitality sector during a pandemic
2021
Abstract In the post-COVID-19 era, the hospitality sector may witness a wider use of mobile payment services (MPS) not requiring physical contact. But consumers may postpone adoption of MPS in wait for a more attractive iteration. Given consumers' reluctance to adapt to such services, an investigation into MPS adoption postponement and the factors contributing to it is thus needed. Our research model extends the innovation resistance theory by including two behavioral measures (privacy concerns and visibility) and examining how security concerns moderate the associations between them. We analyzed data from 308 respondents who had previously purchased accommodation and transportation service…
Motivational Differences? Comparing Private, Public and Hybrid Organizations
2021
AbstractWhile studies of motivational differences between managers in private and public organizations proliferate, few have compared managers’ motivation in hybrid organizations to the motivation of managers in private and public organizations. This lack of studies is surprising, as corporatization has been an important trend in the public sector over the last decades. Using a large survey covering almost 3000 managers from a representative sample of organizations in Norway, this study fills this hole by comparing how managers in hybrid organizations differ on extrinsic, intrinsic and prosocial motivation from their counterparts in public and private organizations.