Search results for "MICI"

Ciò che dicono (e non dicono) le Sezioni Unite sul rapporto tra stalking, omicidio aggravato e lesioni aggravate

2022

Le Sezioni Unite hanno chiarito che il reato di omicidio commesso nei confronti della stessa persona offesa del reato di atti persecutori integra un reato complesso. Il presente contributo esamina le conseguenze che questo principio ha sul tema parallelo del rapporto tra il delitto di atti persecutori e il delitto di lesioni personali aggravate perché commesso dall'autore dello stalking nei confronti della stessa vittima. The United Sections have clarified that the crime of homicide committed against the same offended person as the crime of persecutory acts integrates a complex crime. This article examines the consequences that this principle has on the parallel theme of the relationship be…

Polymeric Nanogels: Nanocarriers For Drug Delivery Application.

2012

The application of nanotechnology to medicine has enabled the development of functionalised nanoparticles that, acting as carriers, can be loaded with drugs or genetic material to be released with a controlled mechanism in specific districts of the organism. Even though nanomedicine is a relative new branch of science, many type of nanocarriers for drug delivery have been developed over the past 30 years, such as liposomes, dendrimers, quantum dots, solid lipid nanoparticles, viruses and virus-like nanoparticles as well as a wide var iety of polymeric nanoparticles. Among these last, in our opinion, nanogels deserve a special attention. Nanogels are nanoscalar polymer networks, with a tende…

Biocompatible polyaniline nanocomposites build a soft interface between biology and opto-electronics

2009

Supramolecular Modification of ABC Triblock Terpolymers in Confinement Assembly

2018

The self-assembly of AB diblock copolymers in three-dimensional (3D) soft confinement of nanoemulsions has recently become an attractive bottom up route to prepare colloids with controlled inner morphologies. In that regard, ABC triblock terpolymers show a more complex morphological behavior and could thus give access to extensive libraries of multicompartment microparticles. However, knowledge about their self-assembly in confinement is very limited thus far. Here, we investigated the confinement assembly of polystyrene-block-poly(4-vinylpyridine)-block-poly(tert-butyl methacrylate) (PS-b-P4VP-b-PT or SVT) triblock terpolymers in nanoemulsion droplets. Depending on the block weight fractio…

Conjugation strategies of insulin to nanogels: new hope for nanogels Alzheimer's disease therapy?

2014

CONJUGATION STRATEGIES OF INSULIN TO NANOGELS AND BIOLOGICAL ACTIVITY TESTS

2014

Radiation engineered functionalized nanogels as platform for biomedical nanocarriers

2011

Radiation sculpured nanogels as platform for novel therapeutic systems

2012

Alcohol-Selective Oxidation in Water under Mild Conditions via a Novel Approach to Hybrid Composite Photocatalysts

2015

Abstract The oxidation of alcohols to carbonyl compounds in a clean fashion (i.e., with water as a solvent or under solvent‐free conditions, and using O2 or H2O2 as the primary oxidant) is the subject of considerable research efforts. A new approach for the selective oxidation of soluble aromatic alcohols in water under mild conditions via a novel composite photocatalyst has been developed. The catalyst is synthesized by grafting 4‐(4‐(4‐hydroxyphenylimino)cyclohexa‐2,5dienylideneamino)phenol and silver nanoparticles onto the surface of moderately crystalline titanium dioxide. The titanium dioxide‐based composite was first extensively characterized and then employed in the catalytic oxidati…

Exploring nose-to-brain insulin delivery as a new strategy for the treatment of Alzheimer’s disease

2019

A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signaling are involved in brain cognitive functions and their dysfunction is implicated in Alzheimer’s disease (AD) degeneration. Thus, administration of insulin could be a strategy for AD treatment. For this aim we designed, synthesized and characterized a nanogel system (NG) to deliver insulin to the brain, as a tool for the development of a new therapy for AD. A carboxyl-functionalized poly(N-vinyl pyrrolidone) nanogel system produced by high energy ionizing radiation was chosen as substrate for the covalent attachment of insulin or fluorescent molecules, relevant for its tracing