Search results for "MICRORNA-21"

MICRORNA-21 EXPRESSION IN VESTIBULAR SCHWANNOMA: POTENTIAL EFFECT ON GROWTH AND POSSIBLE PROGNOSTIC FACTOR

2011

Background: Vestibular schwannomas are benign slow growing tumors arising from VIII cranial nerve. They are potential life threatening benign tumor because of intracranial located. The management could be surgical or conservative, but, left untreated, the tumor preserve the possibility to further growth and complication may arise. The natural history is however not predictable and prognostic factor to select patients manageable conservatively should be studied. The molecular pathways that lead to tumorigenesis and growth are not completely defined and a role could be played by microRNA. Elevated levels of microRNA-21 may contribute to tumor growth by deregulating the tumor suppressor phosph…