Search results for "MIM"

Design, Synthesis, and Biological Evaluation of Novel Fluorinated Ethanolamines

2011

The preparation of novel fluorinated allylamines and their use as key fragments for the stereoselective synthesis of hydroxyethyl secondary amine (HEA)-type peptidomimetics is described. Our strategy employs chiral sulfinyl imines as synthesis intermediates, by treatment of hemiaminal precursors with two equivalents of vinylmagnesium bromide. The subsequent oxidation of the allylic amines to the corresponding epoxides was achieved by treatment with methyl(trifluoromethyl)dioxirane. Finally, epoxide ring opening with a range of nitrogen nucleophiles provided a library of HEA-derived peptidomimetics with a phenyldifluoromethylene moiety. The biological evaluation of these derivatives revealed…

Implementation of IFRS in Japan: An Analysis of Voluntary Adoption by Listed Firms

2019

Since 2010 Japanese listed firms can voluntarily use international financial reporting standards for their consolidated financial statements. Using financial and non-financial data, we carry out a comprehensive research into the adopters’ determinants. We employ a multi-period logit model that considers every annual decision made along the period 2010-2019. We find that the having outside networks through subsidiaries and a strong internal corporate governance system are key factors. We also confirm a contagion effect. Finally, our results suggest that goodwill is also relevant, since only Japanese accounting standards require annual amortization.

The importance of pattern similarity between Müllerian mimics in predator avoidance learning

2004

Müllerian mimicry, where unpalatable prey share common warning patterns, has long fascinated evolutionary biologists. It is commonly assumed that Müllerian mimics benefit by sharing the costs of predator education, thus reducing per capita mortality, although there has been no direct test of this assumption. Here, we specifically measure the selection pressure exerted by avian predators on unpalatable prey with different degrees of visual similarity in their warning patterns. Using wild-caught birds foraging on novel patterned prey in the laboratory, we unexpectedly found that pattern similarity did not increase the speed of avoidance learning, and even dissimilar mimics shared the educatio…

Calculation of the pH and the titratable acidity in clinically used infusion solutions.

2006

Clinically used infusion solutions are complex aqueous mixtures composed of a variety of different salts, acids, and non-electrolytes, and are characterized by composition, initial pH, and titratable acidity (TA). By rigorous treatment as a multi-composed acid-base system, pH and TA were calculated from proton dissociation equilibria, mass balance equations and electroneutrality condition. Nine were arbitrarily chosen as model solutions in which pH and TA were experimentally determined. From composition, and based on a set of apparent acidity constants (pK values) at 37 degrees C and total ionic strength 0.155 mol/l, pH was calculated by iteration. In the model solutions, measured pH was in…

CO2 capture from biogas: Absorbent selection

2013

The development of proper biogas upgrading technology offers a viable means to utilize biogas in conventional power systems. In this paper, various molecular and ionic solvent systems were evaluated for CO2 removal from biogas in a loop reactor system. The performance of amine solutions, ionic liquids and their mixtures, amino acid salts and solutions blended with piperazine was compared in terms of their CO2 loading capacity. The experimental results revealed that addition of small amounts of piperazine can increase on average by 30 vol% the efficiency of above-mentioned solutions. The CO2 capturing capacity achieved for the most promising solvents was in the range of 50–60 L CO2/L absorbe…

Electrochemistry of copper complexes with macrocyclic polyamines containing pyrazole units.

2006

The voltammetric behaviour of bi- and mono-nuclear complexes formed in solution by Cu(2+) with three polyazacyclophanes containing pyrazole units in aqueous solution is described. Cyclic and square wave voltammetric responses at glassy carbon electrodes indicate that the reduction of copper-macrocycle complexes in solution takes place in two successive one-electron per Cu transfer processes coupled with preorganization and protonation reactions that mimic the behaviour of superoxide dismutase. The electrochemistry of ternary Cu(2+)-receptor-dopamine complexes exhibits significant differences with respect to the protection of the neurotransmitter from post-electron transfer cyclization react…

Ontology of Art: Aristotle’s Mimesis and Gadamer’s Play

2018

FIctional Artworks. Literary Ékphrasis and the Invention of Images

2016

The volume is devoted to images in painting, photography and cinema invented by literature. At the same time it intends to question, through this perspective, the relationship between text and image, between verbal and visual in modern and contemporary literature. The authors investigate the mutual boundaries between literature and arts from the point of view of aesthetics, visual culture and literary theory, trying to build a map of the notional ékphrasis, a description which constitutes the work of art while telling it.

An ontology for cognitive mimetics

2018

AI and autonomous systems are intended to replace people in several jobs. People have worked in these jobs being able to execute the required information processing. This implies that new technical artefacts must be able to perform equitably effective information processing. Thus, it makes sense to develop the analysis of human information processing in designing intelligent systems. This approach has been termed cognitive mimetics. This paper studies how it would be practical to gain knowledge about human information processing and organize this knowledge using ontologies.

Questions in Cognitive Mimetics

2021

Human thinking advances through questions and answers. Any field of human endeavor is permeated by the presence of questions, answers and presuppositions. Questions have a kind of universality, whereby one can place the question marks on anything, including questions themselves. The process of asking the right questions about the right things and in the right way are key for the explication of an approach. Recently, we have begun thinking about an approach to the design of intelligent technology: Cognitive mimetics. In brief, the idea is to take inspiration of empirical human thinking in specific contexts to develop AI solutions. The purpose of this article is to question this approach from…