Search results for "MK"
showing 10 items of 136 documents
"I feel that I am a world citizen and don’t really belong anywhere" : investigating linguistic identities of three Finnish missionary kids
2017
Nykyajan globalisoituneessa ja digitalisoituneessa maailmassa monikielisissä ympäristöissä elävien ihmisten lukumäärä kasvaa jatkuvasti. Lähetyslapset ovat erinomainen esimerkki tällaisista ihmisistä, joiden elämässä monikielisyydellä on merkittävä rooli, sillä heidän arkipäivässään on läsnä useampi kieli kuin heidän äidinkielensä. Tällä on luonnollisesti suuri vaikutus myös heidän kielellisiin identiteetteihinsä, sillä nykypäivän kielentutkimuksen näkökulmasta kielen ja identiteetin nähdään olevan lähes erottamattomia toisistaan. Aikaisemmin suomalaisia lähetyslapsia on tutkittu lähinnä kotimaahan paluun jälkeisen suomalaiseen yhteiskuntaan ja koulujärjestelmään jälleensopeutumisen näkökul…
SARS CoV2 infection _The longevity study perspectives
2021
Graphical abstract
Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population
2010
BackgroundAlbeit several studies pointed out the pivotal role that CD4+T cells have in Multiple Sclerosis, the CD8+ T cells involvement in the pathology is still in its early phases of investigation. Proteasome degradation is the key step in the production of MHC class I-restricted epitopes and therefore its activity could be an important element in the activation and regulation of autoreactive CD8+ T cells in Multiple Sclerosis.Methodology/principal findingsImmunoproteasomes and PA28-alphabeta regulator are present in MS affected brain area and accumulated in plaques. They are expressed in cell types supposed to be involved in MS development such as neurons, endothelial cells, oligodendroc…
Circulating MicroRNAs in Extracellular Vesicles as Potential Biomarkers of Alcohol-Induced Neuroinflammation in Adolescence: Gender Differences
2020
Current studies evidence the role of miRNAs in extracellular vesicles (EVs) as key regulators of pathological processes, including neuroinflammation and neurodegeneration. As EVs can cross the blood&ndash
Acute ammonia toxicity is mediated by the NMDA type of glutamate receptors
1992
AbstractPrevious experiments in our laboratory suggested that ammonium toxicity could be mediated by the NMDA type of glutamate receptors. To assess this hypothesis we tested if MK-801, a specific antagonist of the NMDA receptor, is able to prevent ammonium toxicity. Mice and rats were injected i.p. with 12 and 7 mmol/kg of ammonium acetate, respectively, 73% of the mice and 70% of the rats died. However, when the animals were injected i.p. with 2 mg/kg of MK-801, 15 min before ammonium injection, only 5% of the mice and 15% of the rats died. The remarkable protection afforded by MK-801 indicates that ammonia toxicity is mediated by the NMDA receptor.
Pyrolysis-gas chromatography/mass spectrometry of soil organic matter extracted from a Brazilian mangrove and Spanish salt marshes
2009
The soil organic matter (SOM) extracted under different vegetation types from a Brazilian mangrove (Pai Matos Island, São Paulo State) and from three Spanish salt marshes (Betanzos Ría and Corrubedo Natural Parks, Galícia, and the Albufera Natural Park, Valencia) was investigated by pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS). The chemical variation was larger in SOM from the Spanish marshes than in the SOM of the Brazilian mangroves, possibly because the marshes included sites with both tidal and nontidal variation, whereas the mangrove forest underwent just tidal variation. Thus, plant-derived organic matter was better preserved under permanently anoxic environments. Moreove…
Improving the material quality of silicon ingots by aluminum gettering during crystal growth
2016
We present a method for the purification of silicon ingots during the crystallization process that reduces significantly the width of the low charge carrier lifetime region at the ingot top. The back-diffusion of impurities from the ingot top is suppressed by adding a small amount of pure aluminum into the silicon melt right at the end of the solidification. We study the aluminum gettering effect by instrumental neutron activation analysis (INAA) and Fei imaging. Furthermore, we present a model for aluminum gettering of Fe in the silicon ingot that is in agreement with literature data for aluminum gettering at lower temperature. The distribution of iron in the ingots with and without alumin…
The summertime Boreal forest field measurement intensive (HUMPPA-COPEC-2010): an overview of meteorological and chemical influences
2011
This paper describes the background, instrumentation, goals, and the regional influences on the HUMPPACOPEC intensive field measurement campaign, conducted at the Boreal forest research station SMEAR II (Station for Measuring Ecosystem-Atmosphere Relation) in Hyyti¨al¨a, Finland from 12 July–12 August 2010. The prevailing meteorological conditions during the campaign are examined and contrasted with those of the past six years. Back trajectory analyses show that meteorological conditions at the site in 2010 were characterized by a higher proportion of southerly flow than in the other years studied. As a result the summer of 2010 was anomalously warm and high in ozone making the campaign rel…
Skaistumkonkursu aktualitāte un izpratne Latvijas sabiedrībā
2020
Skaistumkonkursu vēsture Latvijā jau ir meklējama 1988. gadā, kad norisinājās pirmais skaistumkonkurss – „Miss Rīga”. Bakalaura darba mērķis ir izprast Latvijas sabiedrības viedokli un izpratni par skaistumkonkursiem un to norises nepieciešamību Latvijā, kā arī padziļinātāk izprast skaistumkonkursa būtību, un iespējamos ietekmes virzienus uz sabiedrību. Teorētiskajā daļā tiek aplūkoti: feminisms, reprezentācija, skaistumkonkursi, skaistumkonkursu sieviešu standarti, skaistumkonkursu ietekme uz modes pasauli, skaistumkonkursu ietekme uz veselību, lai empīriskajā daļā varētu veikt salīdzinājumu, kā bija pagātnē un kā ir tagadnē. Empīriskajā daļā tiek noskaidrots skaistumkonkursa nozīmīgums no…
Spoguļi un gaismu atstarojošas virsmas interjerā
2017
Diplomdarbā “Spoguļi un gaismu atstarojošas virsmas interjerā”, analizējot pieejamo literatūru, tīmeklī esošo informāciju un mēbeļu un buvmateriālu ražotāju piedāvātus materiālus, tiek pētīts jēdziens “gaismu atstārojošās virsmas” un “spogulis”, ka arī gaismu atstārojošu virsmu nepieciešamība un to ietekme projektējot interjeru. Empīriskajā daļā tiek petīti privātie un sabiedriskie interjeri, īpašu uzmanību pieveršot skaistumkopšanas saloniem Latvijā un ārvalstīs. Radošajā daļā, pielietojot ieģutas zināšanas, tiek izstrādāts interjera dizaina projekts skaistumkopšanas salonam. Darbs sastāv no trīs nodaļām: pirmajā nodaļā tiek pētīta spoguļu rašanas vēsture un to evolūcija; otrajā nodaļā - s…