Search results for "MMN"
showing 10 items of 37 documents
Hilbert-Huang versus morlet wavelet transformation on mismatch negativity of children in uninterrupted sound paradigm
2009
Background. Compared to the waveform or spectrum analysis of event-related potentials (ERPs), time-frequency representation (TFR) has the advantage of revealing the ERPs time and frequency domain information simultaneously. As the human brain could be modeled as a complicated nonlinear system, it is interesting from the view of psychological knowledge to study the performance of the nonlinear and linear time-frequency representation methods for ERP research. In this study Hilbert-Huang transformation (HHT) and Morlet wavelet transformation (MWT) were performed on mismatch negativity (MMN) of children. Participants were 102 children aged 8–16 years. MMN was elicited in a passive oddbal…
Mismatch-like event-related potentials to pitch deviances in the cerebellar interpositus nucleus and the effect of its temporary inactivation in rabb…
2000
Evaluation and extraction of mismatch negativity through exploiting temporal, spectral, time-frequency, and spatial features
2010
The effects of long-term native language exposure on event-related potential (ERP) components N1 and MMN in typically reading adults
2009
Auditory duration discrimination in children with reading disorder, attention deficit or both
2009
Tiina Huttunen-Scott tutki väitöskirjassaan kuulonvaraisen keston erottelun ongelmien esiintymistä lapsilla, joilla on vaikeuksia joko lukemisessa, tarkkaavaisuudessa tai molemmissa. Kuullun erottelun ongelmat voivat vaikuttaa puheäänteiden hahmottamiseen ja prosessointiin ja johtaa vaikeuksiin lukemaan oppimisessa.Huttunen-Scott havaitsi kuullun keston erottelun olevan merkitsevästi heikentynyt lapsilla, joilla on lukemisvaikeuksia. Erottelu oli heikentynyt jopa laajemmin lapsilla, joilla on lukemisvaikeuksien ohella myös tarkkaavaisuuden ongelmia. Sen sijaan lapsilla, joilla on vain tarkkaavaisuuden ongelmia, erottelu ei ollut heikentynyt, mikä viittaa siihen, että kuulonvaraisen prosesso…
Processing of word stress related acoustic information : A multi-feature MMN study
2017
In the present study, we investigated the processing of word stress related acoustic features in a word context. In a passive oddball multi-feature MMN experiment, we presented a disyllabic pseudo-word with two acoustically similar syllables as standard stimulus, and five contrasting deviants that differed from the standard in that they were either stressed on the first syllable or contained a vowel change. Stress was realized by an increase of f0, intensity, vowel duration or consonant duration. The vowel change was used to investigate if phonemic and prosodic changes elicit different MMN components. As a control condition, we presented non-speech counterparts of the speech stimuli. Result…
Electrophysiological correlates of memory-based visual change detection in humans
2005
Imbalance between genomic gain and loss identifies high-risk neuroblastoma patients with worse outcomes
2021
Survival in high-risk neuroblastoma (HR-NB) patients remains poor despite multimodal treatment. We aimed to identify HR-NB patients with worse outcomes by analyzing the genomic instability derived from segmental chromosomal aberrations. We calculated 3 genomic instability indexes for primary tumor SNP array profiles from 127 HR-NB patients: (1) Copy number aberration burden (%gainslength+%losseslength), (2) copy number load (CNL) (%gainslength-%losseslength) and (3) net genomic load (NGL) (%gainsamount-%lossesamount). Tumors were classified according to positive or negative CNL and NGL genomic subtypes. The impact of the genomic instability indexes on overall survival (OS) was assessed with…
Processing of word stress related acoustic information : A multi-feature MMN study
2016
In the present study, we investigated the processing of word stress related acoustic features in a word context. In a passive oddball multi-feature MMN experiment, we presented a disyllabic pseudo-word with two acoustically similar syllables as standard stimulus, and five contrasting deviants that differed from the standard in that they were either stressed on the first syllable or contained a vowel change. Stress was realized by an increase of f0, intensity, vowel duration or consonant duration. The vowel change was used to investigate if phonemic and prosodic changes elicit different MMN components. As a control condition, we presented non-speech counterparts of the speech stimuli. Result…
Dysfunction of attention switching networks in amyotrophic lateral sclerosis
2019
Objective To localise and characterise changes in cognitive networks in Amyotrophic Lateral Sclerosis (ALS) using source analysis of mismatch negativity (MMN) waveforms. Rationale The MMN waveform has an increased average delay in ALS. MMN has been attributed to change detection and involuntary attention switching. This therefore indicates pathological impairment of the neural network components which generate these functions. Source localisation can mitigate the poor spatial resolution of sensor-level EEG analysis by associating the sensor-level signals to the contributing brain sources. The functional activity in each generating source can therefore be individually measured and investigat…