Search results for "MOBILITY"
showing 10 items of 922 documents
A Functional Role of IκB-ε in Endothelial Cell Activation
2000
Abstract The NF-κB inhibitor IκB-ε is a new member of the IκB protein family, but its functional role in regulating NF-κB-mediated induction of adhesion molecule expression is unknown. In vascular endothelial cells, IκB-ε associates predominantly with the NF-κB subunit Rel A and to a lesser extent with c-Rel, whereas IκB-α and IκB-β associate with Rel A only. Following stimulation with TNF-α, pyrrolidine dithiocarbamate (PDTC), N-acetylcysteine, and dexamethasone prevented IκB kinase-induced IκB-α, but not IκB-β or IκB-ε phosphorylation and degradation. Since the activation of NF-κB is required for the induction of adhesion molecule expression, we examined the role of IκB-ε in the transacti…
Trace analysis by ion mobility spectrometry: From conventional to smart sample preconcentration methods. A review.
2018
Ion mobility spectrometry (IMS) is a rapid and high sensitive technique widely used in security and forensic areas. However, a lack of selectivity is usually observed in the analysis of complex samples due to the scarce resolution of the technique. The literature concerning the use of conventional and novel smart materials in the pretreatment and preconcentration of samples previous to IMS determinations has been critically reviewed. The most relevant strategies to enhance selectivity and sensitivity of IMS determinations have been widely discussed, based in the use of smart materials, as immunosorbents, aptamers, molecularly imprinted polymers (MIPs), ionic liquids (ILs) and nanomaterial. …
A survey dataset to evaluate the changes in mobility and transportation due to COVID-19 travel restrictions in Australia, Brazil, China, Ghana, India…
2020
COVID-19 pandemic has heavily impacted the global community. To curb the viral transmission, travel restrictions have been enforced across the world. The dataset documents the mobility disruptions and the modal shifts that have occurred as a consequence of the restrictive measures implemented in ten countries: Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa and the United States. An online questionnaire was distributed during the period from the 11st to the 31st of May 2020, with a total of 9 394 respondents. The first part of the survey has characterized the frequency of use of all transport modes before and during the enforcement of the restrictions, while the se…
Contatti di popoli ed etnogenesi delle tribù nomadi sahariane
2006
The contribution focuses on the problem of mobility in the Roman world as a means of contact and collaboration. North Africa was in ancient times a land of cultural exchange, of passage of peoples and people. The research dwells on local identities, studies the origins of these peoples, discusses and tries to understand the ancient dynamics, which led them to clash and meet.
536. Internal and international mobility of Romanian immigrants during the crisis
2016
Para paliar los efectos de la crisis económico-laboral, iniciada en 2007, los inmigrantes han desplegado diversas estrategias, entre las que destaca la movilidad geográfica. El artículo indaga en las migraciones que en los últimos años realizan los rumanos en España y desde España, para lo que se utilizan dos fuentes de información complementarias: la estadística y los testimonios de los inmigrantes. Los resultados de la investigación muestran el notable aumento de la circulación interior de trabajadores durante los primeros años y el progresivo aumento de las salidas, ya sea para retornar al lugar de origen, emigrar a otros países o desplazarse entre diferentes lugares. En general, estos d…
The effect of physical activity counseling on diabetics' mobility : results of a secondary analysis
2013
The preservation of mobility is essential for maintaining an independent and active lifestyle in old age. However, diabetes greatly increases older people’s susceptibility to mobility loss, leading to an increased risk of dependence. Given the increased prevalence of diabetes with age, and the increasing incidence of the disease worldwide, public health initiatives for preventing mobility loss with age must also prove effective for diabetics. The screening and counseling for physical activity among older people (SCAMOB) study examines the effectiveness of physical activity counseling for the prevention of mobility loss in an older population. Although the cohort as a whole has shown positiv…
Human powered mobility per una città più green, equa e sicura.
2014
“Quando una società segna un prezzo sul tempo, tra l’equità e la velocità veicolare si stabilisce una correlazione inversa” Ivan Illich Partendo dall’elogio della bicicletta di Illich (1973) e Augè (2009), il contributo riguarda gli effetti sulla qualità della vita della soft mobility, in termini di riduzione di traffico, inquinamento, tempo impiegato per spostarsi, di riduzione dei consumi energetici, di ‘sostenibilità’ in senso lato, di recupero dello spazio della polis e di equità sociale. Analizzando le indicazioni in merito alla mobilità date dall’Unione Europea affinché si incida su abitudini e stili di vita e sulla conformazione stessa della città, consapevoli che il trasporto pubbli…
Factors contributing to the variability in muscle ageing
2012
a b s t r a c t Ageing is accompanied with a progressive loss of muscle mass and force generating capacity. Ultimately, the muscle wasting and weakness may dramatically impact on mobility and the quality of life, where the elderly has increasing problems with performing activities of daily life, such as rising from a chair or climbing stairs. The rate of structural and functional deterioration of muscle appears to vary considerably between people. Part of the variation in the 'rate of muscle ageing' is attributable to genetic factors, the timing of changes in circulating hormones and the presence or absence of chronic low-grade systemic inflammation. Where an individual cannot change much i…
Inter-industry job mobility in the knowledge economy in Finland
2013
Purpose – The purpose of this paper is to investigate inter-industry labor mobility, paying special attention to workers who move into high-tech (HT) sectors or knowledge-intensive business services (KIBSs). This study inquires whether skilled workers are mobile and whether the characteristics of mobile workers support the effective transfer of knowledge across industries. Design/methodology/approach – Census data representing 7 percent of Finnish residents were used. The micro-econometric estimation method with correction of sample selection bias was applied. Findings – The results show that young workers are the most mobile, whereas mobility decreased for those with previous work experie…
Exploration of future changes of residential locations in an urban agglomeration using an individual-based simulation model (Mobisim)
2015
To ensure that housing supply is suitable to households’ needs and preferences represents a major planning concern. These needs and preferences depend on the households’ characteristics and on their lifecycle changes (union, birth, divorce…). Residential choice factors are numerous (housing and residential environment characteristics) and their role is often different according to the types of households. Residential dynamics involve a great variety of elements, in interaction with each other, and the causal relationships are difficult to identify. Thus, it is not possible to predict the households’ residential behaviour, nor their possible evolutions, without a suitable tool. To study intr…