Search results for "MOE"

showing 10 items of 1101 documents

N-aizvietotu 2-aminomalonskābes monoesteru elektroķīmiska dekarboksilēšana iekšmolekulārā Hofera-Moesta reakcijā.

2021

N-Aizvietotu 2-aminomalonskābes monoesteru elektroķīmiska dekarboksilēšana iekšmolekulārā Hofera-Moesta reakcijā. Prāne K., Darba vadītāja MSc. chem. Koleda O. Bakalaura darbs ir uzrakstīts latviešu valodā, tā apjoms ir 50 lappuses. Darbs satur 16 attēlus, 10 tabulas, 39 literatūras avoti, 1 pielikums. Bakalaura darbā izstrādāta jauna elektroķīmiska N-aizvietotu 2-aminomalonskābes monoesteru dekarboksilēšanas metode, kurā notiek iekšmolekulāra ciklizācija. Izstrādātās reakcijas rezultātā iegūst otrajā pozīcijā ceturtējo oglekli saturošus tetrahidrofurānus un tetrahidropirānus. Iegūtie substrāti un produkti analizēti ar spektroskopijas metodēm.

AMINOMALONĀTIDEKARBOKSILĒŠANAIEKŠMOLEKULĀRA CIKLIZĀCIJAHOFERA-MOESTA REAKCIJAĶīmijaELEKTROLĪZE
researchProduct

Lokanu oglekļa nanocaurulīšu-metālu halkogenīdu hibrīdstruktūru sintēze un īpašības

2021

Darbā ir veikti pētījumi par lokanu oglekļa nanocaurulīšu tīklojumu, oglekļa nanocaurulīšu-metālu halkogenīdu hibrīdstruktūru un to nanokompozītu ar nevadošiem polimēriem termoelektrisko īpašību izmaiņām materiālu lieces iespaidā. Bakalaura darba ietvaros tika sagatavoti lokani oglekļa nanocaurulīšu tīklu un oglekļa nanocaurulīšu-antimona telurīda/ oglekļa nanocaurulīšu-bismuta selenīda hibrīdstruktūru paraugi ar dažādu hibrīdstruktūru sadalījumu parauga tilpumā, kā arī tie tika iemaisīti vai iekapsulēti nevadoša polimēra matricā. Tika pētīta šo paraugu termoelektrisko īpašību (pretestības un Zēbeka koeficienta) atkarība no to liekuma rādiusa, un analizēti iegūtie rezultāti. Šāda tipa parau…

ANTIMONA TELURĪDSOGLEKĻA NANOCAURULĪTESBISMUTA SELENĪDSHIBRĪDSTRUKTŪRASTERMOELEKTRISKIE MATERIĀLIĶīmija
researchProduct

Il Museo della Civiltà contadina di Montallegro

2009

ANTROPOLOGIA ETNOSTORIASettore M-DEA/01 - Discipline Demoetnoantropologiche
researchProduct

Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics

2021

Graphical abstract

ATP Adenosine-triphosphateNBD nucleotide binding domainGSH reduced glutathionePolypharmacologyAlzheimer’s disease (AD)ATP-binding cassette transporterHTS high-throughput screeningBiochemistryABCA7Structural BiologyPLIF protein ligand interactionMSD membrane spanning domainPDB protein data bankTM transmembrane helixABC ATP-binding cassetteMultitarget modulation (PANABC)RMSD root mean square distanceABC transporter (ABCA1 ABCA4 ABCA7)Computer Science ApplicationsMOE Molecular Operating EnvironmentPharmacophoreSNP single-nucleotide polymorphismBiotechnologyResearch ArticleBBB blood-brain barrierBiophysicsDrug designComputational biologyBiologyAD Alzheimer’s diseasePET positron emission tomographyIC intracellular helixAPP amyloid precursor proteincryo-EM cryogenic-electron microscopyGeneticsHomology modelingBinding siteRational drug design and developmentComputingMethodologies_COMPUTERGRAPHICSNBD-cholesterol 7-nitro-2-13-benzoxadiazol-4-yl-cholesterolTransporterPSO particle swarm optimizationPET tracer (PETABC)ECD extracellular domainR-domain/region regulatory domain/regionABCA1biology.proteinEH extracellular helixTP248.13-248.65BODIPY-cholesterol 44-difluoro-4-bora-3a4a-diaza-s-indacene-cholesterolComputational and Structural Biotechnology Journal
researchProduct

<title>Ion and electron trapping: release and relaxation processes in fluoride crystals</title>

2001

The thermally stimulated relaxation (TSR) processes in CaF2, BaF2 and LiBaF3 crystals (X-ray irradiated at LNT or RT) have been investigated by means of the ionic conductivity, thermally stimulated (TS) ionic depolarization current (TSDC), TS current (TSC), TS luminescence (TSL) and thermal bleaching techniques. The ionic TSDC measurements evidence that under DC field fluorides accumulate large ionic space-charge (thermoelectric state is formed) as a result of the migrating anion interstitial and/or vacancy capture on defects. In the ionic conductivity region (290 - 650 K) the thermoelectric state anneals, and several wide and overlapping anionic TSDC peaks are detected. The ionic TSDC stag…

Absorption bandChemistryVacancy defectThermoelectric effectRelaxation (NMR)Analytical chemistryIonic bondingIonic conductivityThermoelectric materialsIonOptical Organic and Inorganic Materials
researchProduct

Thermoelectric properties of CoTiSb based compounds

2009

Several CoTiSb based compounds were synthesized and investigated on their thermoelectric properties. The aim was to improve the thermoelectric properties of CoTiSb by the systematic substitution of atoms or the introduction of additional Co into the vacant sublattice. The solid solutions Co1+xTiSb, Co1?yCuyTiSb and CoTiSb1?zBiz were synthesized. X-ray diffraction was used to investigate the crystal structure. The resistivity, the Seebeck coefficient and the thermal conductivity were determined for all compounds in the temperature range from 2 to 400?K. The highest figure of merit for each solid solution is presented. We were able to improve the figure of merit by a factor of approximately s…

Acoustics and Ultrasonicsbusiness.industryChemistryAnalytical chemistryAtmospheric temperature rangeCondensed Matter PhysicsSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsOpticsThermal conductivityElectrical resistivity and conductivitySeebeck coefficientThermoelectric effectX-ray crystallographyFigure of meritbusinessSolid solutionJournal of Physics D: Applied Physics
researchProduct

Chromoendoscopy with indigocarmine improves the detection of adenomatous and nonadenomatous lesions in the colon.

2001

BACKGROUND AND STUDY AIMS Depressed early cancers and flat adenomas have a high potential for malignancy with possible infiltrating growth, despite the small size of the lesion. Japanese investigators have shown that early diagnosis and classification of these lesions is possible with the help of chromoendoscopy. The aim of this study, therefore, was to evaluate the usefulness of chromoendoscopy during routine colonoscopy. PATIENTS AND METHODS During routine colonoscopy, vital staining with indigocarmine solution (0.4 %, 1 - 10 ml) was performed on all visible lesions in 100 consecutive patients without visible inflammatory changes. If findings on macroscopic examination were unremarkable, …

AdenomaAdultMalePathologymedicine.medical_specialtyColonColonoscopyRectumColonic PolypsMalignancyIndigo CarmineSensitivity and SpecificityChromoendoscopyLesionmedicineHumansColoring AgentsAgedmedicine.diagnostic_testStaining and Labelingbusiness.industryGastroenterologySigmoid colonColonoscopyMiddle Agedmedicine.diseasemedicine.anatomical_structureDysplasiaAdenocarcinomaFemalemedicine.symptombusinessColorectal NeoplasmsEndoscopy
researchProduct

Perspectives of Chromo and Magnifying Endoscopy

2003

The goal of every routine endoscopy in the gut is the early diagnosis of malignant and premalignant changes of the mucosa. Chromo- and magnifying endoscopes are exciting new tools and offer detailed analysis of the colonic mucosal surface and pit pattern architecture. This review summarizes recent advances in endoscopic characterization of colorectal lesions using magnification endoscopy and chromoendoscopy. Surface analysis of the colon using chromoendoscopy allows a prediction between non-neoplastic and neoplastic lesions with high specificity. The precise delineation of the borders and a more detailed macroscopic analysis of the lesions are further advantages. In particular, flat adenoma…

AdenomaPathologymedicine.medical_specialtyEndoscopeAdenomaRectumColonoscopySensitivity and SpecificityChromoendoscopymedicineHumansGastrointestinal NeoplasmsIntraepithelial neoplasiaStaining and Labelingmedicine.diagnostic_testbusiness.industryGastroenterologyColonoscopymedicine.diseaseUlcerative colitisEndoscopyMethylene Bluemedicine.anatomical_structureColitis UlcerativeGentian VioletbusinessForecastingJournal of Clinical Gastroenterology
researchProduct

The ‘Difficult’ Polyp: Pitfalls for Endoscopic Removal

2012

Adenomatous polyps are early neoplasias of colorectal cancer (adenoma-carcinoma sequence). The majority of adenomas or early invasive cancers (T1sm1) can be resected by endoscopy. Endoscopic resection techniques include classic loop polypectomy, endoscopic mucosectomy with preceding lifting of the (almost flat) lesion, endoscopic submucosal dissection and transanal microsurgical resection, an alternative to endoscopic submucosal dissection in the rectum. Endoscopic polyp removal should always aim to resect the lesion in ‘one piece’ and avoid, whenever possible, ‘piecemeal resection’. One-piece polypectomy is the basis for a precise histopathological analysis and for proving complete removal…

Adenomamedicine.medical_specialtyAdenomamedicine.medical_treatmentPerforation (oil well)Blood Loss SurgicalColonic PolypsMalignancyGastroenterologyChromoendoscopyInternal medicineSubmucosamedicineHumansNeoplasm Invasivenessmedicine.diagnostic_testbusiness.industryGastroenterologyColonoscopyGeneral Medicinemedicine.diseasePolypectomyEndoscopymedicine.anatomical_structureIntestinal PerforationColorectal PolypRadiologyColorectal NeoplasmsbusinessDigestive Diseases
researchProduct

Chromo- and magnifying endoscopy for colorectal lesions

2005

It is essential to identify patients with premalignant or early malignant changes during colonoscopy. Thus, curative resection can be offered. At present, endoscopy can be performed with new powerful high-resolution or magnifying endoscopes. Comparably to the rapid development in chip technology, the optic features of the newly designed endoscopes offer resolutions which allow new mucosal surface details to be seen. In conjunction with chromoendoscopy, the newly discovered tool video endoscopy is much easier and more impressive than with conventional fibre optics. This review summarizes the value of magnifying endoscopy in the lower gastrointestinal tract and focuses on colorectal lesions.

Adenomamedicine.medical_specialtyEndoscopeColonColorectal cancerColonoscopyRectumEndoscopy GastrointestinalChromoendoscopyDiagnosis DifferentialColonic DiseasesIntestinal mucosamedicineHumansIntestinal MucosaHepatologymedicine.diagnostic_testbusiness.industryGeneral surgeryMagnifying endoscopyRectumGastroenterologymedicine.diseaseEndoscopyRectal Diseasesmedicine.anatomical_structureChromogenic CompoundsPractice Guidelines as TopicColitis UlcerativeColorectal NeoplasmsbusinessEuropean Journal of Gastroenterology & Hepatology
researchProduct