Search results for "MOE"
showing 10 items of 1101 documents
Future perspectives in hepatocellular carcinoma.
2010
Hepatocellular carcinoma (HCC) is one of the most common and lethal malignancies worldwide. Due to late diagnosis and advanced underlying liver cirrhosis, only limited treatment options with marginal clinical benefits have been available in up to 70% of patients. However, major progress has been achieved with regard to surveillance, early diagnosis, and multimodal treatment approaches during the last years leading to an improvement in prognosis. Particularly, the increasing knowledge of molecular hepatocarcinogenesis today provides the opportunity for targeted therapy. The multikinase inhibitor sorafenib has broadened the therapeutic horizon for patients with advanced disease and is current…
Transarterial chemoembolization and sorafenib in patients with intermediate-stage hepatocellular carcinoma: time to enter routine clinical practice?
2015
According to the guidelines of the European Association for the Study of the Liver (EASL), patients affected from hepatocellular carcinoma (HCC) can be classified according to the Barcelona Clinic Liver Cancer (BCLC) staging system. This classification system divides HCC patients in five stages (0, A, B, C and D) on the basis of a number of prognostic and treatment- related variables such as tumor status and liver function. A specific treat ment approach is then proposed for each of the above-mentioned stages. Transarterial chemoembolization (TACE) is recommended as first-line therapy in the treatment of patients with intermediate-stage (BCLC-B class) HCC [1]. The efficacy of this procedure…
CCDC 1556028: Experimental Crystal Structure Determination
2017
Related Article: Lotta Turunen, Fangfang Pan, Ngong Kodiah Beyeh, Mario Cetina, John F. Trant, Robin H. A. Ras, Kari Rissanen|2017|CrystEngComm|19|5223|doi:10.1039/C7CE01118K
CCDC 244396: Experimental Crystal Structure Determination
2005
Related Article: C.M.Grunert, P.Weinberger, J.Schweifer, C.Hampel, A.F.Stassen, K.Mereiter, W.Linert|2005|J.Mol.Struct.|733|41|doi:10.1016/j.molstruc.2004.07.036
CCDC 616336: Experimental Crystal Structure Determination
2007
Related Article: N.Rodriguez, C.R.de Arellano, G.Asensio, M.Medio-Simon|2007|Chem.-Eur.J.|13|4223|doi:10.1002/chem.200601488
CCDC 1574171: Experimental Crystal Structure Determination
2017
Related Article: Lotta Turunen, Fangfang Pan, Ngong Kodiah Beyeh, John F. Trant, Robin H. A. Ras, Kari Rissanen|2018|Cryst.Growth Des.|18|513|doi:10.1021/acs.cgd.7b01517
HPLC-DAD-ESI-MS2analytical profile of extracts obtained from purple sweet potato after green ultrasound-assisted extraction
2016
International audience; Ultrasound pre-treatment (UAE) was applied to assist the extraction of valuable compounds (polyphenols (especially anthocyanins), and proteins) from purple sweet potato (PSP). Under optimum conditions (ultrasound time (40 min); supplementary hot extraction (80 °C) up to 120 min; pH: 2.5; ethanol concentration: 58%), the highest concentrations of polyphenols (3.877 mg/g), anthocyanins (0.293 mg/g), and proteins (0.753 mg/g) were found, with minimal specific energy consumption (8406 J/mg).Moreover, anthocyanin and non-anthocyanin polyphenols in PSP extract from optimized extraction temperature were identified using HPLC-DAD-ESI-MS2. The major identified anthocyanins we…
3D Morphology, ultrastructure and development of Ceratomyxa puntazzi stages: first insights into the mechanisms of motility and budding in the Myxozo…
2012
Free, amoeboid movement of organisms within media as well as substrate-dependent cellular crawling processes of cells and organisms require an actin cytoskeleton. This system is also involved in the cytokinetic processes of all eukaryotic cells. Myxozoan parasites are known for the disease they cause in economical important fishes. Usually, their pathology is related to rapid proliferation in the host. However, the sequences of their development are still poorly understood, especially with regard to pre-sporogonic proliferation mechanisms. The present work employs light microscopy (LM), electron microscopy (SEM, TEM) and confocal laser scanning microscopy (CLSM) in combination with specific…
Thermal conductance of thin film YIG determined using Bayesian statistics
2015
Thin film YIG (${\mathrm{Y}}_{3}{\mathrm{Fe}}_{5}{\mathrm{O}}_{12}$) is a prototypical material for experiments on thermally generated pure spin currents and the spin Seebeck effect. The $3\ensuremath{\omega}$ method is an established technique to measure the cross-plane thermal conductance of thin films, but cannot be used in YIG/GGG (${\mathrm{Ga}}_{3}{\mathrm{Gd}}_{5}{\mathrm{O}}_{12}$) systems in its standard form. We use two-dimensional modeling of heat transport and introduce a technique based on Bayesian statistics to evaluate measurement data taken from the $3\ensuremath{\omega}$ method. Our analysis method allows us to study material systems that have not been accessible with the c…