Search results for "MOM"

showing 10 items of 3704 documents

Psammomatoid Calcification-Rich Oncocytic Thyroid Adenoma With Clear-Cell Change

2018

Abundant calcifications and clear-cell change may occur in oncocytic thyroid adenoma (OTA). We aimed to report the features of a case of OTA peculiar by the presence of extensive calcifications and of a clear-cell component. The OTA was detected on a right thyroid lobectomy specimen. Clear-cell change was observed in 15%-20% of the cells. Numerous, focally confluent psammomatoid calcifications, resulting in macrocalcifications, were identified. The nodule cells, uni- or multinucleated oncocytes, including those with clear cytoplasm, expressed heterogeneously TTF1, S100 protein, Bcl2, CD10, as well as CD138 and CD56. Lipid-droplet markers adipophilin and TIP47 were also expressed. In conclus…

0301 basic medicineMicrobiology (medical)oncocytePathologymedicine.medical_specialtyHistologyAdenomanoduleOncocytePathology and Forensic Medicineclear cellcalcification03 medical and health sciences0302 clinical medicinehemic and lymphatic diseasesmedicinelcsh:PathologyThyroidbusiness.industryThyroid adenomaThyroidNodule (medicine)medicine.diseasepsammomatoid/psammoma-like/pseudo-psammomamitochondria030104 developmental biologymedicine.anatomical_structure030220 oncology & carcinogenesisimmunohistochemistryCommentaryImmunohistochemistryadenomamedicine.symptombusinessClear cellCalcificationlcsh:RB1-214Clinical Pathology
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Comparative evaluation of antimicrobial efficacy of three herbal irrigants in reducing intracanal E. faecalis populations: An in vitro study

2016

Background: The present study aimed to evaluate the intracanal bacterial reduction promoted by chemomechanical preparation using three different herbal extracts named Ocimum sanctum (OS), Cinnamomum zeylanicum (CZ), Syzygium aromaticum (SA) against Enterococcus faecalis. Material and Methods: Root canals from extracted teeth were contaminated with Enterococcus faecalis ATCC 29212 for 7 days and then randomly distributed into 3 experimental groups of 10 teeth each: which includes conventional irrigation with OS, CZ and SA. The control groups included 5 teeth each consisting of NaOCl (positive control) and distilled water (negative control). Samples taken before and after chemomechanical proc…

0301 basic medicineOdontologíaEnterococcus faecalisOperative Dentistry and EndodonticsMicrobiologyComparative evaluation03 medical and health sciences0302 clinical medicineMedicineIn vitro studyGeneral DentistrybiologyTraditional medicinebusiness.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Antimicrobialbiology.organism_classificationOcimumCiencias de la saludCinnamomum zeylanicum030104 developmental biologyDistilled waterSyzygiumUNESCO::CIENCIAS MÉDICASbusinessJournal of Clinical and Experimental Dentistry
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Application of chemometrics to assess the influence of ultrasound frequency, Lactobacillus sakei culture and drying on beef jerky manufacture: Impact…

2017

The effects of ultrasound (US) frequency, addition of Lactobacillus sakei culture and drying time on key nutritional (protein, amino acids, and organic acids) and physicochemical properties (texture and colour) of cultured and uncultured beef jerky were evaluated. Cultured and uncultured jerky samples were subjected to US frequencies of 25 kHz, 33 kHz and 45 kHz for 30 min prior to marination and drying. Principal component analysis demonstrated a significant effect of beef jerky processing conditions on physicochemical properties. Taurine content of jerky samples was found to increase with an increase in ultrasonic frequencies for cultured samples. No significant changes in colour values w…

0301 basic medicinePhysicochemical propertiesFood HandlingColony Count MicrobialColorMarinationAnalytical ChemistryChemometrics03 medical and health sciences0404 agricultural biotechnologyLatilactobacillus sakeiDrying timeOrganic acidsUltrasoundAnimalsFood scienceTexture (crystalline)Amino AcidsDryingchemistry.chemical_classification030109 nutrition & dieteticsbiologyChemistrybusiness.industryLactobacillus sakeiUltrasoundfood and beverages04 agricultural and veterinary sciencesGeneral MedicineBeef jerky productionbiology.organism_classification040401 food scienceAmino acidLactobacillus sakeiLactobacillusRed MeatInteractive effectsAmino acidsCattlebusinessFood ScienceFood Chemistry
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A New Experiment for the Measurement of the g-Factors of 3He+ and 3He2+.

2018

We describe a new experiment that aims at a parts per billion measurement of the nuclear magnetic moment of 3He2+ and a 100 parts per trillion measurement of the Zeeman effect of the ground-state hyperfine splitting of 3He+. To enable ultrafast and efficient experiment cycles the experiment relies on new technologies such as sympathetic laser cooling of single 3He-ions coupled to a cloud of Doppler-cooled 9Be-ions in a Penning trap or a novel spin-state detection scheme.

0301 basic medicinePhysicsHistoryZeeman effectPenning trap01 natural sciencesComputer Science ApplicationsEducation03 medical and health sciencessymbols.namesake030104 developmental biologyLaser coolingTheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITY0103 physical sciencesNuclear magnetic momentsymbolsPhysics::Atomic PhysicsAtomic physicsPräzisionsexperimente - Abteilung Blaum010306 general physicsUltrashort pulseHyperfine structure
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Searching for Chymase Inhibitors among Chamomile Compounds Using a Computational-Based Approach

2018

Inhibitors of chymase have good potential to provide a novel therapeutic approach for the treatment of cardiovascular diseases. We used a computational approach based on pharmacophore modeling, docking, and molecular dynamics simulations to evaluate the potential ability of 13 natural compounds from chamomile extracts to bind chymase enzyme. The results indicated that some chamomile compounds can bind to the active site of human chymase. In particular, chlorogenic acid had a predicted binding energy comparable or even better than that of some known chymase inhibitors, interacted stably with key amino acids in the chymase active site, and appeared to be more selective for chymase than other …

0301 basic medicineProteaseschlorogenic acidlcsh:QR1-502030204 cardiovascular system & hematologyMolecular Dynamics SimulationCrystallography X-RayLigandsBiochemistrylcsh:MicrobiologyArticleSerine03 medical and health sciences0302 clinical medicineChymasesCatalytic DomainHumanschamomilecardiovascular diseases; chamomile; chlorogenic acid; chymase; docking; matricin; molecular dynamics simulations; pharmacophore; Biochemistry; Molecular BiologyEnzyme InhibitorsMolecular Biologychymasechemistry.chemical_classificationBinding SitesbiologypharmacophoreChymaseActive sitemolecular dynamics simulationsmatricinAmino acidcardiovascular diseasesMolecular Docking Simulation030104 developmental biologyEnzymechemistryBiochemistryDocking (molecular)dockingbiology.proteinPharmacophoreBiomolecules
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A Tuft Cell-Like Signature Is Highly Prevalent in Thymic Squamous Cell Carcinoma and Delineates New Molecular Subsets Among the Major Lung Cancer His…

2020

Abstract Introduction In-depth genomic characterization of thymic epithelial tumors (TETs), comprising thymomas and thymic carcinomas (TCs), failed to identify targetable mutations and suggested unique biology of TETs, including KIT expression in most TCs. Recently, tuft cell–like medullary thymic epithelial cells were identified in the murine thymus, and our reanalysis of the published gene expression data revealed that these cells express KIT. In addition, recently, a minor subset of SCLCs with tuft cell–like features was described. Methods We interrogated mRNA expression data from our tumor cohorts (N = 60) and publicly available, independent data sets from TETs and NSCLC (N = 1199) for …

0301 basic medicinePulmonary and Respiratory MedicineLung NeoplasmsThymomaurologic and male genital diseasesmedicine.disease_cause03 medical and health sciencesMice0302 clinical medicinemedicineAnimalsHumansLung cancerThymic carcinomaThymic Squamous Cell Carcinomaurogenital systembusiness.industryCancerThymus Neoplasmsmedicine.diseasePhenotypeSmall Cell Lung Carcinomafemale genital diseases and pregnancy complications3. Good health030104 developmental biologyOncology030220 oncology & carcinogenesisCancer researchCarcinoma Squamous CellImmunohistochemistryTuft cellbusinessCarcinogenesisJournal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
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The marine activities performed within the TOMO-ETNA experiment

2016

<p>The TOMO-ETNA experiment was planned in order to obtain a detailed geological and structural model of the continental and oceanic crust beneath Mt. Etna volcano and northeastern Sicily up to the Aeolian Islands (southern Italy), by integrating data from active and passive refraction and reflection seismic methodologies, magnetic and gravity surveys. This paper focuses on the marine activities performed within the experiment, which have been carried out in the Ionian and Tyrrhenian Seas, during three multidisciplinary oceanographic cruises, involving three research vessels (“Sarmiento de Gamboa”, “Galatea” and “Aegaeo”) belonging to different countries and institutions. During the o…

0301 basic medicineSeismometerlcsh:QC851-999010502 geochemistry & geophysicsRemotely operated vehicle01 natural sciencesSonarGravity anomalyEtna offshore; Ionian and Tyrrhenian Seas; Marine geophysical data acquisition; Scientific cruise report; Geophysics03 medical and health sciencesSeismic refraction0105 earth and related environmental sciencesMarine geophysical data acquisitionIonian and Tyrrhenian Seaslcsh:QC801-809Ionian and Tyrrhenian SeaSeafloor spreadinglcsh:Geophysics. Cosmic physics030104 developmental biologyGeophysicsSeismic tomographyScientific cruise reportEtna offshorelcsh:Meteorology. ClimatologySubmarine pipelineGeologySeismologyAnnals of Geophysics
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Effects of innovative and conventional sanitizing treatments on the reduction of Saccharomycopsis fibuligera defects on industrial durum wheat bread

2016

Wickerhamomyces anomalus, Hyphopichia burtonii and Saccharomycopsis fibuligera are spoilage yeasts causing chalk mold defects on sliced bread packaged under modified atmosphere. The first objective of this study, carried out in a bread-making company for two consecutive years, was to genetically identify yeasts isolated from spoiled sliced bread in Modified Atmosphere Packaging (MAP) and to determine the dominant species among identified strains. The second objective was to evaluate the effects of hydrogen peroxide and silver solution 12% (HPS) treatment in the leavening cells and cooling chambers, in comparison with the conventional Ortho-Phenylphenol (OPP) fumigating treatment, on the inc…

0301 basic medicineWater activityBaked goodsWickerhamomyces anomalus030106 microbiologyFood spoilageSaccharomycopsismedicine.disease_causeMicrobiology03 medical and health sciences0404 agricultural biotechnologyYeastsMoldmedicineBaked goodFood scienceChalk mold defects; Baked goods; 26S sequencing; MAP packaging; Water activity; Environmental biodecontaminationTriticumLeavening agent26S sequencingChalk mold defectChemistryEnvironmental biodecontaminationTemperatureMAP packagingWaterBreadHydrogen Peroxide04 agricultural and veterinary sciencesGeneral MedicineSettore AGR/15 - Scienze E Tecnologie AlimentariContamination040401 food scienceYeastRNA RibosomalModified atmosphereChalk mold defectsFood ScienceWater activity
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Aerobic catabolism and respiratory lactate bypass in Ndh-negative Zymomonas mobilis

2018

Ability to ferment in the presence of oxygen increases the robustness of bioprocesses and opens opportunity for novel industrial setups. The ethanologenic bacterium Zymomonas mobilis performs rapid and efficient anaerobic ethanol fermentation, yet its respiratory NADH dehydrogenase (Ndh)-deficient strain (ndh-) is known to produce ethanol with high yield also under oxic conditions. Compared to the wild type, it has a lower rate of oxygen consumption, and an increased expression of the respiratory lactate dehydrogenase (Ldh). Here we present a quantitative study of the product spectrum and carbon balance for aerobically growing ndh-. Ldh-deficient and Ldh-overexpressing ndh- strains were con…

0301 basic medicinelcsh:BiotechnologyEndocrinology Diabetes and Metabolism030106 microbiologyBiomedical EngineeringRespiratory chainBioethanolEthanol fermentationZymomonas mobilisArticle03 medical and health scienceschemistry.chemical_compoundlcsh:TP248.13-248.65Lactate dehydrogenaselcsh:QH301-705.5biologyCatabolismZymomonas mobilisNADH dehydrogenaseLactate dehydrogenaseNADH dehydrogenaseMetabolismRespiratory chainbiology.organism_classificationlcsh:Biology (General)chemistryBiochemistryOxidative stressbiology.proteinAnaerobic exerciseMetabolic Engineering Communications
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Protective Effect of Astaxanthin on Primary Retinal Cells of the GerbilPsammomys ObesusCultured in DiabeticMilieu

2016

Astaxanthin is a major marine carotenoid with powerful antioxidant and neuroprotective properties. The in vitro protective effect of astaxanthin in adult retinal cells of the type-2 diabetic model Psammomys obesus in hyperglycemic conditions was investigated. Primary retinal cells were cultured in normal (5 mM) or high concentrations of glucose (25 and 40 mM) for 5 days and treated with 1–20 µM astaxanthin for the last 48 h of culturing. Mitochondrial dehydrogenase activity and cell viability were assessed using MTT test and trypan blue exclusion dye. Retinal cells were characterized by immunohistochemistry. The results showed that mitochondrial function increased significantly (P < 0.05) w…

0301 basic medicinemedicine.medical_specialtyAntioxidantmedicine.medical_treatmentBiophysicsGerbilNeuroprotection03 medical and health scienceschemistry.chemical_compound0302 clinical medicineAstaxanthinInternal medicinemedicineViability assayPharmacologybiologyRetinalCell Biologybiology.organism_classification030104 developmental biologyEndocrinologychemistryBiochemistry030221 ophthalmology & optometryTrypan bluePsammomysFood ScienceJournal of Food Biochemistry
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