Search results for "MORBIDITY"

showing 10 items of 986 documents

Risk Factors and Number of Falls as Determinants of Quality of Life of Community-Dwelling Older Adults.

2019

Background and purpose In older adults, the psychological impact and effects related to the loss of functional capacity are directly related to perceived quality of life (QOL). The predictors of better QOL are increased physical activity, lower prevalence of overweight, lower cases of depression, and lower rate of reported alcohol abuse. On the contrary, the predictors of decreased QOL are female gender, comorbidity, deficient nutritional condition, polypharmacy, loss of mobility, depression and dependency, poor economic conditions, and social isolation and loneliness. Furthermore, QOL in older adults is more dependent on the number of falls than comorbidity. The objective was to investigat…

MaleCross-sectional studyPoison controlAlcohol abuseComorbidityOverweight03 medical and health sciences0302 clinical medicineQuality of lifeRisk FactorsInjury preventionmedicineHumans030212 general & internal medicineExerciseGeriatric AssessmentAgedPolypharmacyAged 80 and overbusiness.industryDepressionRehabilitationOverweightmedicine.diseaseComorbidityCross-Sectional StudiesQuality of LifeAccidental FallsFemaleIndependent LivingGeriatrics and Gerontologymedicine.symptombusiness030217 neurology & neurosurgeryDemographyCentral Nervous System AgentsJournal of geriatric physical therapy (2001)
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Lifetime self-reported arthritis is associated with elevated levels of mental health burden: A multi-national cross sectional study across 46 low- an…

2017

Population-based studies investigating the relationship of arthritis with mental health outcomes are lacking, particularly among low- and middle-income countries (LMICs). We investigated the relationship between arthritis and mental health (depression spectrum, psychosis spectrum, anxiety, sleep disturbances and stress) across community-dwelling adults aged ≥18 years across 46 countries from the World Health Survey. Symptoms of psychosis and depression were established using questions from the Mental Health Composite International Diagnostic Interview. Severity of anxiety, sleep problems, and stress sensitivity over the preceding 30 days were self-reported. Self-report lifetime history of a…

MaleCross-sectional studyPsychological interventionArthritisComorbidityGlobal Health0302 clinical medicineQUALITY-OF-LIFEOdds RatioPrevalencePublic Health Surveillance030212 general & internal medicineGENERAL-POPULATIONINFECTED PATIENTSeducation.field_of_studyMultidisciplinaryQRMiddle Aged3. Good healthMental HealthDEPRESSIVE SYMPTOMSIncomeMedicineAnxietyFemalemedicine.symptomAdultmedicine.medical_specialtySciencePopulationArticleYoung Adult03 medical and health sciencesmedicineHumansPsychiatryeducationDeveloping CountriesSLEEP PROBLEMSbusiness.industryArthritisOdds ratioGLOBAL BURDENSTRESS SENSITIVITYmedicine.diseaseComorbidityMental healthPSYCHOTIC EXPERIENCESRHEUMATOID-ARTHRITISCross-Sectional StudiesPHYSICAL-ACTIVITYSocial ClassSelf Reportbusiness030217 neurology & neurosurgeryScientific Reports
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Developing and validating a novel multisource comorbidity score from administrative data: a large population-based cohort study from Italy

2017

ObjectiveTo develop and validate a novel comorbidity score (multisource comorbidity score (MCS)) predictive of mortality, hospital admissions and healthcare costs using multiple source information from the administrative Italian National Health System (NHS) databases.MethodsAn index of 34 variables (measured from inpatient diagnoses and outpatient drug prescriptions within 2 years before baseline) independently predicting 1-year mortality in a sample of 500 000 individuals aged 50 years or older randomly selected from the NHS beneficiaries of the Italian region of Lombardy (training set) was developed. The corresponding weights were assigned from the regression coefficients of a Weibull sur…

MaleDatabases FactualKaplan-Meier Estimate030204 cardiovascular system & hematologySettore MED/42 - Igiene Generale E ApplicataSeverity of Illness IndexState MedicineCohort Studies0302 clinical medicineHealth careMedicineHospital Mortality1506Settore SECS-S/05 - Statistica Sociale030212 general & internal medicineMedical diagnosisAged 80 and overeducation.field_of_studyHealth Care CostsGeneral MedicineMiddle Agedprognostic scoreHospitalizationcomorbidityItalyadministrative databaseRegression AnalysisFemaleRisk AdjustmentPublic HealthCohort studyPopulationDrug PrescriptionsSettore MED/01 - Statistica Medica03 medical and health sciencesHumans1724Medical prescriptioneducationSurvival analysisAgedReceiver operating characteristicbusiness.industryResearchmedicine.diseaseComorbidityROC Curverecord linkagebusinessDemographyBMJ Open
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Incidence, risk factors, clinical characteristics and outcomes of deep venous thrombosis in patients with COVID-19 attending the Emergency Department…

2021

Background and importance A higher incidence of venous thromboembolism [both pulmonary embolism and deep vein thrombosis (DVT)] in patients with coronavirus disease 2019 (COVID-19) has been described. But little is known about the true frequency of DVT in patients who attend emergency department (ED) and are diagnosed with COVID-19. Objective We investigated the incidence, risk factors, clinical characteristics and outcomes of DVT in patients with COVID-19 attending the ED before hospitalization. Methods We retrospectively reviewed all COVID patients diagnosed with DVT in 62 Spanish EDs (20% of Spanish EDs, case group) during the first 2 months of the COVID-19 outbreak. We compared DVT-COVI…

MaleDeep veinComorbidity030204 cardiovascular system & hematologyChest pain0302 clinical medicineRisk Factorsrisk factorsclinical characteristicsIncidenceIncidence (epidemiology)Age FactorsVenous ThromboembolismMiddle AgedPulmonary embolismVenous thrombosismedicine.anatomical_structureEmergency MedicineoutcomeFemalemedicine.symptomEmergency Service Hospitalsevere acute respiratory syndrome coronavirus 2Adultmedicine.medical_specialtyRisk Assessment03 medical and health sciencescoronavirus disease 2019Internal medicineThromboembolismmedicineHumanscardiovascular diseasesTromboembolismeAgedRetrospective Studiesdeep venous thrombosisbusiness.industryCOVID-19030208 emergency & critical care medicineRetrospective cohort studyOriginal ArticlesEmergency departmentOdds ratiomedicine.diseaseSpainCase-Control StudiesincidencePulmonary Embolismbusiness
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Correlates of Human Herpesvirus-8 DNA detection among adults in Italy without Kaposi sarcoma.

2005

Background: The presence of Human Herpesvirus-8 (HHV8) DNA is predictive of Kaposi sarcoma (KS) among patients with HIV-associated or iatrogenic immunosuppression. However, correlates of HHV8-DNA detection in the general population remain undefined. Methods: We assessed correlates of HHV8-DNA detection among Italian adults without KS who had antibodies against HHV8-latent nuclear antigen by immunofluorescence assay. HHV8-K6 DNA sequences were detected in peripheral blood mononuclear cells using TaqMan CR. Results: Of the 158 subjects 26 (16.5%) had detectable HHV8-DNA [median copies/million cells, 53; (13-2128)]. Adjusted for age, sex, and laboratory, HHV8-DNA was detected more frequently i…

MaleEpidemiologymedicine.medical_treatmentComorbiditySettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeKaposi sarcoma herpesvirus80 and overLeukocytesGammaherpesvirinaeMedicineHHV8ViralAged 80 and overeducation.field_of_studybiologyvirus diseasesImmunosuppressionGeneral MedicineHerpesviridae InfectionsMiddle AgedViral LoadItalyHerpesvirus 8 HumanFemaleAntibodyKaposi sarcoma herpesviruViral loadHumanAdultViral DNAPopulationMononuclearKSHVPeripheral blood mononuclear cellHerpesviridaeAge DistributionAntigenHumansHerpesvirus 8Sex DistributioneducationAgedbusiness.industryHemodynamicsDNAbiology.organism_classificationBlood Cell CountSocioeconomic FactorsImmunologyDNA Viralbiology.proteinLeukocytes MononuclearbusinessInternational journal of epidemiology
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Children from broken homes: visits to the school nurse.

1980

Children from broken homes, especially females, have an increased tendency to visit the school nurse. Complaints are often ill-defined, possibly psychosomatic. These children may require additional medical and emotional support from the school nurse. The effect the broken home may have upon a student has important implications for the physical and emotional health of today's youth. An awareness of this finding can provide school nursing personnel valuable insight in the assessment of students who visit the school nurse.

MaleFamily CharacteristicsEmotional healthEmotional supportbusiness.industryeducationPublic Health Environmental and Occupational HealthPrimary educationPsychophysiologic DisordersUnited StatesEducationSchool nursingPhilosophySchool nurseNursingDivorceEvaluation Studies as TopicSchool NursingMedicineHumansFemaleMorbiditybusinessChildThe Journal of school health
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A high-density SNP linkage scan with 142 combined subtype ADHD sib pairs identifies linkage regions on chromosomes 9 and 16

2008

As part of the International Multi-centre ADHD Gene (IMAGE) project we have completed an affected sibling pair study of 142 narrowly defined DSM-IV combined type ADHD proband-sibling pairs. We found suggestive linkage on chromosomes 9 and 16 with non-parametric multipoint peak LOD scores of 2.13 and 3.1 respectively. There have been several previous ADHD linkage scans. The UCLA study (Fisher et al. 2002; Ogdie et al. 2004; Ogdie et al. 2003), the Dutch study (Bakker et al. 2003), the German study (Hebebrand et al. 2006) and the MGH Study (Faraone et al., submitted) applied the affected sib pair (ASP) strategy; the Columbian study used extended pedigrees ascertained from a population isolate…

MaleGenetics and epigenetic pathways of disease [NCMLS 6]GENOMEWIDE SCANMedizin2804 Cellular and Molecular NeuroscienceCHILDRENComorbidityNeuroinformatics [DCN 3]Severity of Illness IndexDevelopmental psychology2738 Psychiatry and Mental Health0302 clinical medicinePerception and Action [DCN 1]HETEROGENEITYIsraelChildGeneticsObserver Variation0303 health sciencesATTENTION-DEFICIT/HYPERACTIVITY DISORDERPSYCHIATRIC-DISORDERSDOPAMINE TRANSPORTER GENEASSOCIATION10058 Department of Child and Adolescent PsychiatryEuropePsychiatry and Mental healthFemalePsychologyChromosomes Human Pair 9linkageFunctional Neurogenomics [DCN 2]GenotypeDEFICIT HYPERACTIVITY DISORDER610 Medicine & healthPolymorphism Single NucleotideMental health [NCEBP 9]Genetic determinismWhite PeopleGenomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciencesCellular and Molecular NeuroscienceCognitive neurosciences [UMCN 3.2]Genetic linkage1312 Molecular BiologymedicineSNPAttention deficit hyperactivity disorderHumansADHDSiblingMolecular Biology030304 developmental biologyLinkage (software)SiblingsChromosomemedicine.diseaseSib pairsUnited Statesaffected sib pairsGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with HyperactivityCONDUCT DISORDERLod ScoreDISEQUILIBRIUM030217 neurology & neurosurgeryChromosomes Human Pair 16
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Frailty and other geriatric conditions for risk stratification of older patients with acute coronary syndrome

2014

Background Geriatric conditions may predict outcomes beyond age and standard risk factors. Our aim was to investigate a wide spectrum of geriatric conditions in survivors after an acute coronary syndrome. Methods A total of 342 patients older than 65 years were included. At hospital discharge, 5 geriatric conditions were evaluated: frailty (Fried and Green scores), physical disability (Barthel index), instrumental disability (Lawton-Brody scale), cognitive impairment (Pfeiffer questionnaire), and comorbidity (Charlson and simple comorbidity indexes). The outcomes were postdischarge mortality and the composite of death/myocardial infarction during a 30-month median follow-up. Results Seventy…

MaleGerontologyAcute coronary syndromemedicine.medical_specialtyFrail ElderlyMyocardial InfarctionComorbidityRisk AssessmentCohort StudiesRisk FactorsInternal medicineActivities of Daily LivingmedicineHumansProspective StudiesMyocardial infarctionAcute Coronary SyndromeGeriatric AssessmentAgedProportional Hazards ModelsAged 80 and overHand StrengthReceiver operating characteristicProportional hazards modelbusiness.industryHazard ratioPrognosismedicine.diseaseComorbidityROC CurveArea Under CurveMultivariate AnalysisExercise TestFemaleCognition DisordersCardiology and Cardiovascular MedicineRisk assessmentbusinessCohort studyAmerican Heart Journal
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Multimorbidity increases the risk for sarcopenia onset: Longitudinal analyses from the English Longitudinal Study of Ageing.

2021

Background-\ud \ud Cross-sectional studies have demonstrated that multimorbidity is associated with sarcopenia. However, to date, this association has not been extensively investigated longitudinally. Therefore, the aim of the present paper was to explore the association between multimorbidity at baseline and sarcopenia onset over 12 years of follow-up in a large representative sample of the English older adult population.\ud \ud Methods-\ud \ud Representative data from the English Longitudinal Study of Ageing (ELSA) were analyzed. Multimorbidity at baseline was defined as ≥2 medical conditions, of 17 conditions included. Participants were considered to have sarcopenia if they had low handg…

MaleGerontologyAgingLongitudinal studySarcopeniaEpidemiologyPopulationComorbidityLogistic regressionELSABiochemistryEndocrinologyGeneticsmedicineHumansMass indexLongitudinal StudieseducationMolecular BiologyAgededucation.field_of_studyHand Strengthbusiness.industryConfoundingCohortMultimorbidityCell Biologymedicine.diseaseComorbidityAgeing; Cohort; Comorbidity; ELSA; Epidemiology; Multimorbidity; Older adults; Prospective; Sarcopenia; Aged; Aging; Cross-Sectional Studies; Female; Hand Strength; Humans; Longitudinal Studies; Male; Multimorbidity; Sarcopeniabody regionsAgeing Cohort Comorbidity ELSA Epidemiology Multimorbidity Older adults Prospective Sarcopenia Aged Aging Cross-Sectional Studies Female Hand Strength Humans Longitudinal Studies Male Multimorbidity SarcopeniaAgeingProspectiveCross-Sectional StudiesSarcopeniaOlder adultsCohortFemalebusinesshuman activities
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Health literacy supports active aging

2020

From the individual viewpoint, active aging refers to the ability of older persons, depending on their goals, functional capacity and opportunities, to engage in desired activities. This study investigated the role of health literacy in active aging among persons differing in their number of chronic conditions. Data were collected from 948 individuals, 57% women, aged 75, 80 and 85 in 2017–2018 in the city of Jyväskylä in Central Finland. Health literacy was assessed with the 16-question version of the European Health Literacy Survey (HLS-EU-Q16), active aging with the University of Jyväskylä Active Aging Scale (UJACAS) and self-reported physician-diagnosed chronic conditions. Both health l…

MaleGerontologyAginghealth promotionEpidemiologyCross-sectional studyterveysosaaminenhealth promotion [http://www.yso.fi/onto/yso/p12732]01 natural sciences0302 clinical medicineSurveys and QuestionnairesMedicine030212 general & internal medicinekohorttitutkimusFinlandInformaatiotutkimuksen päivätAged 80 and overMiddle AgedPredictive value3. Good healthScale (social sciences)FemaleMultiple Chronic ConditionsPsychologyikääntyneetCohort studymultimorbidityHealth literacyterveyden edistäminen03 medical and health sciencestoimintakykycomorbidity [http://www.yso.fi/onto/yso/p18495]cohort studyHumans0101 mathematicsDepressive symptomsAgedbusiness.industryaging010102 general mathematicsPublic Health Environmental and Occupational Healthgerontology [http://www.yso.fi/onto/yso/p468]lcsh:Zlcsh:Bibliography. Library science. Information resourcesHealth LiteracyikääntyminenCross-Sectional StudiesHealth promotionPhysical performancebusinesshealth literacyPreventive Medicine
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